Monitoring Patient Respiratory Effort During Mechanical Ventilation: Lung and Diaphragm-Protective Ventilation by Michele Bertoni, Savino Spadaro, Ewan C. Goligher

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A manifesto for the future of ICU trials by Ewan C. Goligher, Fernando Zampieri, Carolyn S. Calfee, Christopher W. Seymour

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The influence of drugs used for sedation during mechanical ventilation on respiratory pattern during unassisted breathing and assisted mechanical ventilation: a physiological syste... by Danica Quickfall, Michael C. Sklar, George Tomlinson, Ani Orchanian-Cheff, Ewan C. Goligher

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Helmet interface increases lung volumes at equivalent ventilator pressures compared to the face mask interface during non-invasive ventilation by Kate C. Tatham, Matthew Ko, Lisa Palozzi, Stephen E. Lapinsky, Laurent J. Brochard, Ewan C. Goligher

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Effect of inspiratory synchronization during pressure-controlled ventilation on lung distension and inspiratory effort by Nuttapol Rittayamai, François Beloncle, Ewan C. Goligher, Lu Chen, Jordi Mancebo, Jean-Christophe M. Richard, Laurent Brochard

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Lung- and diaphragm-protective strategies in acute respiratory failure: an in silico trial by Damian Ratano, Binghao Zhang, Jose Dianti, Dimitrios Georgopoulos, Laurent J. Brochard, Timothy C. Y. Chan, Ewan C. Goligher

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Diaphragm echodensity in mechanically ventilated patients: a description of technique and outcomes by Benjamin Coiffard, Stephen Riegler, Michael C. Sklar, Martin Dres, Stefannie Vorona, W. Darlene Reid, Laurent J. Brochard, Niall D. Ferguson, Ewan C. Goligher

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Association of different positive end-expiratory pressure selection strategies with all-cause mortality in adult patients with acute respiratory distress syndrome by Manuel Tisminetzky, Jose Dianti, Bruno L. Ferreyro, Federico Angriman, Lorenzo Del Sorbo, Sachin Sud, Daniel Talmor, Eddy Fan, Niall D. Ferguson, Ary Serpa Neto, Neill K. J. Adhikari, Ewan C. Goligher

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Impact of Supine Versus Semirecumbent Body Posture on the Distribution of Ventilation in Acute Respiratory Distress Syndrome by Alex K. Pearce, MD, W. Cameron McGuire, MD, MPH, Ann R. Elliott, PhD, Ewan C. Goligher, MD, PhD, G. Kim Prisk, PhD, James P. Butler, PhD, Atul Malhotra, MD

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A novel non-invasive method to detect excessively high respiratory effort and dynamic transpulmonary driving pressure during mechanical ventilation by Michele Bertoni, Irene Telias, Martin Urner, Michael Long, Lorenzo Del Sorbo, Eddy Fan, Christer Sinderby, Jennifer Beck, Ling Liu, Haibo Qiu, Jenna Wong, Arthur S. Slutsky, Niall D. Ferguson, Laurent J. Brochard, Ewan C. Goligher

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Statistical Power and Performance of Strategies to Analyze Composites of Survival and Duration of Ventilation in Clinical Trials by Ziming Chen, MSc, Michael O. Harhay, PhD, Eddy Fan, MD, PhD, Anders Granholm, MD, Daniel F. McAuley, MD, Martin Urner, MD, Christopher J. Yarnell, MD, Ewan C. Goligher, MD, PhD, Anna Heath, PhD

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Helmet noninvasive support for acute hypoxemic respiratory failure: rationale, mechanism of action and bedside application by Melania Cesarano, Domenico Luca Grieco, Teresa Michi, Laveena Munshi, Luca S. Menga, Luca Delle Cese, Ersilia Ruggiero, Tommaso Rosà, Daniele Natalini, Michael C. Sklar, Salvatore L. Cutuli, Filippo Bongiovanni, Gennaro De Pascale, Bruno L. Ferreyro, Ewan C. Goligher, Massimo Antonelli

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Strategies for lung- and diaphragm-protective ventilation in acute hypoxemic respiratory failure: a physiological trial by Jose Dianti, Samira Fard, Jenna Wong, Timothy C. Y. Chan, Lorenzo Del Sorbo, Eddy Fan, Marcelo B. Passos Amato, John Granton, Lisa Burry, W. Darlene Reid, Binghao Zhang, Damian Ratano, Shaf Keshavjee, Arthur S. Slutsky, Laurent J. Brochard, Niall D. Ferguson, Ewan C. Goligher

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EXpert consensus On Diaphragm UltraSonography in the critically ill (EXODUS): a Delphi consensus statement on the measurement of diaphragm ultrasound-derived parameters in a critic... by Mark E. Haaksma, Jasper M. Smit, Alain Boussuges, Alexandre Demoule, Martin Dres, Giovanni Ferrari, Paolo Formenti, Ewan C. Goligher, Leo Heunks, Endry H. T. Lim, Lidwine B. Mokkink, Eleni Soilemezi, Zhonghua Shi, Michele Umbrello, Luigi Vetrugno, Emmanuel Vivier, Lei Xu, Massimo Zambon, Pieter R. Tuinman

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Duration of diaphragmatic inactivity after endotracheal intubation of critically ill patients by Michael Chaim Sklar, Fabiana Madotto, Annemijn Jonkman, Michela Rauseo, Ibrahim Soliman, L. Felipe Damiani, Irene Telias, Sebastian Dubo, Lu Chen, Nuttapol Rittayamai, Guang-Qiang Chen, Ewan C. Goligher, Martin Dres, Remi Coudroy, Tai Pham, Ricard M. Artigas, Jan O. Friedrich, Christer Sinderby, Leo Heunks, Laurent Brochard

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The association of antiplatelet agents with mortality among patients with non–COVID-19 community-acquired pneumonia: a systematic review and meta-analysis by Sylvain A. Lother, Lana Tennenhouse, Rasheda Rabbani, Ahmed M. Abou-Setta, Nicole Askin, Alexis F. Turgeon, Srinivas Murthy, Brett L. Houston, Donald S. Houston, Asher A. Mendelson, Jonathan D. Paul, Michael E. Farkouh, Jovan Hasmatali, Barret Rush, Joel Nkosi, Ewan C. Goligher, Emily Rimmer, John C. Marshall, Souradet Y. Shaw, Patrick R. Lawler, Yoav Keynan, Ryan Zarychanski

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