Age-dependent decline in cardiac function in guanidinoacetate-N-methyltransferase knockout mice by Aksentijević, D, Zervou, S, Eykyn, TR, McAndrew, DJ, Lygate, CA, Wallis, J, Schneider, JE, Neubauer, S

SGLT2 inhibitors and the cardiac Na+/H+ exchanger-1: the plot thickens by Chung, YJ, Park, KC, Tokar, S, Eykyn, TR, Fuller, W, Pavlovic, D, Swietach, P, Shattock, MJ

Off-target effects of sodium-glucose co-transporter 2 blockers: empagliflozin does not inhibit Na+/H+ exchanger-1 or lower [Na+]i in the heart by Chung, YJ, Park, KC, Tokar, S, Eykyn, TR, Fuller, W, Swietach, P, Pavlovic, D, Shattock, MJ

MITOCHONDRIAL FUSION PROTEIN OPA1 AS A TARGET FOR NEUROPROTECTION IN NEONATAL HYPOXIA-ISCHAEMIA BRAIN INJURY by Ane Goikolea-Vives, Bethan Mead, Adam Jones, Claire Curel, Gwladys Chabrier, Richard Southworth, Thomas Eykyn, Claire Thornton

Get full text

Age-Dependent Decline in Cardiac Function in Guanidinoacetate-N-Methyltransferase Knockout Mice by Dunja Aksentijević, Sevasti Zervou, Thomas R. Eykyn, Debra J. McAndrew, Julie Wallis, Jurgen E. Schneider, Stefan Neubauer, Craig A. Lygate

Get full text

Subtle role for adenylate kinase 1 in maintaining normal basal contractile function and metabolism in the murine heart by Zervou, S, McAndrew, DJ, Whittington, HJ, Lake, HA, Park, KC, Cha, KM, Ostrowski, PJ, Eykyn, TR, Schneider, JE, Neubauer, S, Lygate, CA

Over-expression of mitochondrial creatine kinase in the murine heart improves functional recovery and protects against injury following ischaemia-reperfusion by Whittington, H, Ostrowski, P, McAndrew, D, Cao, F, Shaw, A, Eykyn, T, Lake, H, Tyler, J, Schneider, J, Neubauer, S, Zervou, S, Lygate, C

Proteomic and metabolomic changes driven by elevating myocardial creatine suggest novel metabolic feedback mechanisms. by Zervou, S, Yin, X, A Nabeebaccus, A, O'Brien, B, L Cross, R, McAndrew, D, Atkinson, R, Eykyn, T, Mayr, M, Neubauer, S, Lygate, C

Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1 by Maia Kavanagh Williamson, Naomi Coombes, Florian Juszczak, Marios Athanasopoulos, Mariam B. Khan, Thomas R. Eykyn, Ushani Srenathan, Leonie S. Taams, Julianna Dias Zeidler, Andrea T. Da Poian, Hendrik Huthoff

Get full text

Serogroup-specific epidemiology of Streptococcus pneumoniae: associations with age, sex, and geography in 7,000 episodes of invasive disease. by Scott, J, Hall, A, Dagan, R, Dixon, J, Eykyn, S, Fenoll, A, Hortal, M, Jetté, L, Jorgensen, J, Lamothe, F, Latorre, C, Macfarlane, J, Shlaes, D, Smart, L, Taunay, A

Intracellular sodium elevation reprograms cardiac metabolism by Dunja Aksentijević, Anja Karlstaedt, Marina V. Basalay, Brett A. O’Brien, David Sanchez-Tatay, Seda Eminaga, Alpesh Thakker, Daniel A. Tennant, William Fuller, Thomas R. Eykyn, Heinrich Taegtmeyer, Michael J. Shattock

Get full text

Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles by Chris G. Faulkes, Thomas R. Eykyn, Jan Lj. Miljkovic, James D. Gilbert, Rebecca L. Charles, Hiran A. Prag, Nikayla Patel, Daniel W. Hart, Michael P. Murphy, Nigel C. Bennett, Dunja Aksentijevic

Get full text

Lactate and choline metabolites detected in vitro by nuclear magnetic resonance spectroscopy are potential metabolic biomarkers for PI3K inhibition in pediatric glioblastoma. by Nada M S Al-Saffar, Lynley V Marshall, L Elizabeth Jackson, Geetha Balarajah, Thomas R Eykyn, Alice Agliano, Paul A Clarke, Chris Jones, Paul Workman, Andrew D J Pearson, Martin O Leach

Get full text

Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies. by Gigin Lin, Gabriela Andrejeva, Anne-Christine Wong Te Fong, Deborah K Hill, Matthew R Orton, Harry G Parkes, Dow-Mu Koh, Simon P Robinson, Martin O Leach, Thomas R Eykyn, Yuen-Li Chung

Get full text

Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data. by Deborah K Hill, Matthew R Orton, Erika Mariotti, Jessica K R Boult, Rafal Panek, Maysam Jafar, Harold G Parkes, Yann Jamin, Maria Falck Miniotis, Nada M S Al-Saffar, Mounia Beloueche-Babari, Simon P Robinson, Martin O Leach, Yuen-Li Chung, Thomas R Eykyn

Get full text

Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart by Sevasti Zervou, Sevasti Zervou, Debra J. McAndrew, Debra J. McAndrew, Hannah J. Whittington, Hannah J. Whittington, Hannah A. Lake, Hannah A. Lake, Kyung Chan Park, Kyung Chan Park, Kyung Chan Park, Kuan Minn Cha, Kuan Minn Cha, Philip J. Ostrowski, Philip J. Ostrowski, Thomas R. Eykyn, Jürgen E. Schneider, Stefan Neubauer, Stefan Neubauer, Craig A. Lygate, Craig A. Lygate

Get full text