AAV-mediated Sirt1 overexpression in skeletal muscle activates oxidative capacity but does not prevent insulin resistance by Laia Vil, Carles Roca, Ivet Elias, Alba Casellas, Ricardo Lage, Sylvie Franckhauser, Fatima Bosch

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Long-term retinal PEDF overexpression prevents neovascularization in a murine adult model of retinopathy. by Virginia Haurigot, Pilar Villacampa, Albert Ribera, Assumpcio Bosch, David Ramos, Jesus Ruberte, Fatima Bosch

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Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells. by Joan Teichenne, Meritxell Morró, Alba Casellas, Veronica Jimenez, Noelia Tellez, Adrien Leger, Fatima Bosch, Eduard Ayuso

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AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease by Laia Vilà, Ivet Elias, Carles Roca, Albert Ribera, Tura Ferré, Alba Casellas, Ricardo Lage, Sylvie Franckhauser, Fatima Bosch

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AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer. by Miguel A Muñoz-Lorente, Paula Martínez, Águeda Tejera, Kurt Whittemore, Ana Carolina Moisés-Silva, Fàtima Bosch, Maria A Blasco

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Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. by Yi-Chun Loraine Tung, Eduard Ayuso, Xiaoye Shan, Fatima Bosch, Stephen O'Rahilly, Anthony P Coll, Giles S H Yeo

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Integrated gene expression profiles reveal a transcriptomic network underlying the thermogenic response in adipose tissue by Jordi Rodó, Miquel Garcia, Estefania Casana, Sergio Muñoz, Claudia Jambrina, Victor Sacristan, Sylvie Franckhauser, Ignasi Grass, Veronica Jimenez, Fatima Bosch

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Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis. by Miguel García, Anna Pujol, Albert Ruzo, Efrén Riu, Jesús Ruberte, Anna Arbós, Anna Serafín, Beatriz Albella, Juan Emilio Felíu, Fátima Bosch

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Overexpressing high levels of human vaspin limits high fat diet-induced obesity and enhances energy expenditure in a transgenic mouse by Inka Rapöhn, Ivet Elias, Ivet Elias, Juliane Weiner, Anna Pujol, Anna Pujol, Stephanie Kehr, Alexandra Chadt, Alexandra Chadt, Hadi Al-Hasani, Hadi Al-Hasani, Ralph Burkhardt, Nora Klöting, Michael Stumvoll, Michael Stumvoll, Fatima Bosch, Fatima Bosch, Peter Kovacs, Peter Kovacs, John T. Heiker, John T. Heiker, Jana Breitfeld

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AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice by Cristina Mallol, Estefania Casana, Veronica Jimenez, Alba Casellas, Virginia Haurigot, Claudia Jambrina, Victor Sacristan, Meritxell Morró, Judith Agudo, Laia Vilà, Fatima Bosch

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Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres by Juan Manuel Povedano, Paula Martinez, Rosa Serrano, Águeda Tejera, Gonzalo Gómez-López, Maria Bobadilla, Juana Maria Flores, Fátima Bosch, Maria A Blasco

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Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver. by Roxana Khatib Shahidi, Jenny M Hoffmann, Shahram Hedjazifar, Laurianne Bonnet, Ritesh K Baboota, Stephanie Heasman, Christopher Church, Ivet Elias, Fatima Bosch, Jeremie Boucher, Ann Hammarstedt, Ulf Smith

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BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice by Jenny M. Hoffmann, John R. Grünberg, Ann Hammarstedt, Tobias Kroon, Thomas U. Greiner, Stefanie Maurer, Ivet Elias, Vilborg Palsdottir, Fatima Bosch, Jeremie Boucher, Shahram Hedjazifar, Ulf Smith

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Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa by Alonso Sánchez-Cruz, Alberto Hernández-Pinto, Concepción Lillo, Carolina Isiegas, Miguel Marchena, Ignacio Lizasoain, Fátima Bosch, Pedro de la Villa, Catalina Hernández-Sánchez, Enrique J. de la Rosa

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Protein kinase C delta (PKCδ) affects proliferation of insulin-secreting cells by promoting nuclear extrusion of the cell cycle inhibitor p21Cip1/WAF1. by Felicia Ranta, Johannes Leveringhaus, Dorothea Theilig, Gabriele Schulz-Raffelt, Anita M Hennige, Dominic G Hildebrand, René Handrick, Verena Jendrossek, Fatima Bosch, Klaus Schulze-Osthoff, Hans-Ulrich Häring, Susanne Ullrich

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Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC by Sara Marcó, Anna Pujol, Carles Roca, Sandra Motas, Albert Ribera, Miguel Garcia, Maria Molas, Pilar Villacampa, Cristian S. Melia, Víctor Sánchez, Xavier Sánchez, Joan Bertolin, Jesús Ruberte, Virginia Haurigot, Fatima Bosch

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AAV-mediated BMP7 gene therapy counteracts insulin resistance and obesity by Estefania Casana, Veronica Jimenez, Claudia Jambrina, Victor Sacristan, Sergio Muñoz, Jordi Rodo, Ignasi Grass, Miquel Garcia, Cristina Mallol, Xavier León, Alba Casellas, Víctor Sánchez, Sylvie Franckhauser, Tura Ferré, Sara Marcó, Fatima Bosch

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Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist by Francois Moreau, Nicholas S. Kirk, Fa Zhang, Vasily Gelfanov, Edward O. List, Martina Chrudinová, Hari Venugopal, Michael C. Lawrence, Veronica Jimenez, Fatima Bosch, John J. Kopchick, Richard D. DiMarchi, Emrah Altindis, C. Ronald Kahn

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Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs by Maria Luisa Jaén, Laia Vilà, Ivet Elias, Veronica Jimenez, Jordi Rodó, Luca Maggioni, Rafael Ruiz-de Gopegui, Miguel Garcia, Sergio Muñoz, David Callejas, Eduard Ayuso, Tura Ferré, Iris Grifoll, Anna Andaluz, Jesus Ruberte, Virginia Haurigot, Fatima Bosch

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Treatment of skeletal and non-skeletal alterations of Mucopolysaccharidosis type IVA by AAV-mediated gene therapy by Joan Bertolin, Víctor Sánchez, Albert Ribera, Maria Luisa Jaén, Miquel Garcia, Anna Pujol, Xavier Sánchez, Sergio Muñoz, Sara Marcó, Jennifer Pérez, Gemma Elias, Xavier León, Carles Roca, Veronica Jimenez, Pedro Otaegui, Francisca Mulero, Marc Navarro, Jesús Ruberte, Fatima Bosch

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