Germline landscape of RPA1, RPA2 and RPA3 variants in pediatric malignancies: identification of RPA1 as a novel cancer predisposition candidate gene by Richa Sharma, Ninad Oak, Wenan Chen, Rose Gogal, Martin Kirschner, Martin Kirschner, Fabian Beier, Fabian Beier, Michael J. Schnieders, Maria Spies, Kim E. Nichols, Marcin Wlodarski

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Peripheral blood CD3+HLADR+ cells and associated gut microbiome species predict response and overall survival to immune checkpoint blockade by Joao Gorgulho, Joao Gorgulho, Christoph Roderburg, Christoph Roderburg, Fabian Beier, Fabian Beier, Carsten Bokemeyer, Tim H. Brümmendorf, Tim H. Brümmendorf, Tom Luedde, Tom Luedde, Sven H. Loosen, Sven H. Loosen

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Transient elastography in adult patients with cryptic dyskeratosis congenita reveals subclinical liver fibrosis: a retrospective analysis of the Aachen telomere biology disease reg... by Mareike Tometten, Martin Kirschner, Susanne Isfort, Marie-Luise Berres, Tim H. Brümmendorf, Fabian Beier

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Effects of senolytic drugs on human mesenchymal stromal cells by Clara Grezella, Eduardo Fernandez-Rebollo, Julia Franzen, Mónica Sofia Ventura Ferreira, Fabian Beier, Wolfgang Wagner

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Eltrombopag Preserves the Clonogenic Potential of Hematopoietic Stem Cells During Treatment With Antithymocyte Globulin in Patients With Aplastic Anemia by Margherita Vieri, Benjamin Rolles, Maria Crocioni, Mirle Schemionek-Reinders, Susanne Isfort, Jens Panse, Tim H. Brümmendorf, Fabian Beier

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Effective treatment of advanced Hodgkin lymphoma with a modified BEACOPP regimen for a patient with demyelinating hereditary motor and sensory neuropathy type 1 (HMSN1) by Patrick P. Hess, Monica S. Ventura Ferreira, Benjamin Rolles, Martin Kirschner, Florian Holtbernd, Mareike Tometten, Tim H. Brümmendorf, Fabian Beier

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Revesz syndrome revisited by Michael Karremann, Eva Neumaier-Probst, Frank Schlichtenbrede, Fabian Beier, Tim H. Brümmendorf, Friedrich W. Cremer, Peter Bader, Matthias Dürken

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Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions by Benjamin Werner, Fabian Beier, Sebastian Hummel, Stefan Balabanov, Lisa Lassay, Thorsten Orlikowsky, David Dingli, Tim H Brümmendorf, Arne Traulsen

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Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Cong... by Margherita Vieri, Martin Kirschner, Mareike Tometten, Anne Abels, Benjamin Rolles, Susanne Isfort, Jens Panse, Tim H. Brümmendorf, Fabian Beier

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GERMLINE LOSS-OF-FUNCTION MUTATIONS IN MDM4 CAUSE A NEW BONE MARROW FAILURE SYNDROME WITH TP53- DEPENDENT HEMATOPOIETIC CELL DEATH by Richa Sharma, Senthil Velan Bhoopalan, Robert Meyer, Lei Han, Shondra M. Pruett-Miller, Claudia Khurana, Miriam Erlacher, Jean Soulier, Fabian Beier, Marcin Wlodarski

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Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta by Mónica S. Ventura Ferreira, Michaela Bienert, Katrin Müller, Björn Rath, Tamme Goecke, Christian Opländer, Till Braunschweig, Petra Mela, Tim H. Brümmendorf, Fabian Beier, Sabine Neuss

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Infliximab therapy together with tyrosine kinase inhibition targets leukemic stem cells in chronic myeloid leukemia by Oliver Herrmann, Maja Kim Kuepper, Marlena Bütow, Ivan G. Costa, Iris Appelmann, Fabian Beier, Tom Luedde, Till Braunschweig, Steffen Koschmieder, Tim H. Brümmendorf, Mirle Schemionek

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Myelofibrosis at diagnosis is associated with the failure of treatment-free remission in CML patients by Henrike Jacobi, Henrike Jacobi, Margherita Vieri, Margherita Vieri, Marlena Bütow, Marlena Bütow, Carolina Y. Namasu, Laura Flüter, Ivan G. Costa, Tiago Maié, Katharina Lindemann-Docter, Nicolas Chatain, Nicolas Chatain, Fabian Beier, Fabian Beier, Michael Huber, Wolfgang Wagner, Wolfgang Wagner, Wolfgang Wagner, Martina Crysandt, Martina Crysandt, Tim H. Brümmendorf, Tim H. Brümmendorf, Mirle Schemionek, Mirle Schemionek

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P762: HEMATOPOIETIC PROGENITOR CELL-REACTIVE T CELL CLONES CAN RECOGNIZE VIRAL EPITOPES IN APLASTIC ANEMIA BONE MARROW by Amin Ben Hamza, Carlotta Welters, Monika Brüggemann, Kerstin Dietze, Lars Bullinger, Tim H Brümmendorf, Thomas Winkler, Julian Strobel, Holger Hackstein, Klaus Dornmair, Fabian Beier, Leo Hansmann

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Application of wearables for remote monitoring of oncology patients: A scoping review by Katharina Cloß, Marlo Verket, Dirk Müller-Wieland, Nikolaus Marx, Katharina Schuett, Edgar Jost, Martina Crysandt, Fabian Beier, Tim H Brümmendorf, Guido Kobbe, Julia Brandts, Malte Jacobsen

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The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling by Kathrin Olschok, Kathrin Olschok, Bianca Altenburg, Bianca Altenburg, Marcelo A. S. de Toledo, Marcelo A. S. de Toledo, Angela Maurer, Angela Maurer, Anne Abels, Anne Abels, Fabian Beier, Fabian Beier, Deniz Gezer, Deniz Gezer, Susanne Isfort, Susanne Isfort, Katrin Paeschke, Katrin Paeschke, Tim H. Brümmendorf, Tim H. Brümmendorf, Martin Zenke, Martin Zenke, Nicolas Chatain, Nicolas Chatain, Steffen Koschmieder, Steffen Koschmieder

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P1008: THE TELOMERASE INHIBITOR IMETELSTAT DIFFERENTIALLY TARGETS JAK2V617F- VERSUS CALR-MUTANT MYELOPROLIFERATIVE NEOPLASM CELLS AND INHIBITS JAK-STAT SIGNALING by Kathrin Olschok, Bianca Altenburg, Marcelo A.S. de Toledo, Angela Maurer, Anne Abels, Fabian Beier, Deniz Gezer, Susanne Isfort, Tim H Brümmendorf, Martin Zenke, Nicolas Chatain, Steffen Koschmieder

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Epigenetic Clocks Are Not Accelerated in COVID-19 Patients by Julia Franzen, Selina Nüchtern, Vithurithra Tharmapalan, Margherita Vieri, Miloš Nikolić, Yang Han, Paul Balfanz, Nikolaus Marx, Michael Dreher, Tim H. Brümmendorf, Edgar Dahl, Fabian Beier, Wolfgang Wagner

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P653: CML LONG-TERM LEUKEMIC STEM CELL PERSISTENCE IS INFLUENCED BY MYELOFIBROSIS AT DIAGNOSIS by Henrike Jacobi, Margherita Vieri, Carolina Y. Namasu, Laura Flüter, Ivan G. Costa, Tiago Maié, Nicolas Chatain, Fabian Beier, Michael Huber, Martina Crysandt, Tim H. Brümmendorf, Mirle Schemionek-Reinders

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Telomere length dynamics measured by flow-FISH in patients with obesity undergoing bariatric surgery by Benjamin Rolles, Monica S. V. Ferreira, Margherita Vieri, Karl P. Rheinwalt, Sophia M. Schmitz, Patrick H. Alizai, Ulf Neumann, Tim H. Brümmendorf, Fabian Beier, Tom F. Ulmer, Mareike Tometten

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