The 4th NextGen therapies of SJIA and MAS, part 4: it is time for IL-18 based trials in systemic juvenile idiopathic arthritis? by Scott W. Canna, Fabrizio De Benedetti

Get full text

The 4th NextGen therapies for SJIA and MAS: part 3 clinical trials in refractory SJIA: historic controls as an alternative to a withdrawal design study by Fabrizio de Benedetti, Alexei A. Grom, Hermine Brunner

Get full text

Proceedings from the 4th NextGen Therapies for SJIA and MAS virtual symposium held February 13–14, 2022 by Rashmi Sinha, Fabrizio De Benedetti, Alexei A. Grom, on behalf of the participants listed below

Get full text

Is fibrodysplasia ossificans progressiva an interleukin-1 driven auto-inflammatory syndrome? by Ruby Haviv, Veronica Moshe, Fabrizio De Benedetti, Giusi Prencipe, Noa Rabinowicz, Yosef Uziel

Get full text

Identification of a Novel Mutation in TNFAIP3 in a Family With Poly-Autoimmunity by Marianna Nicoletta Rossi, Silvia Federici, Andrea Uva, Chiara Passarelli, Camilla Celani, Ivan Caiello, Valentina Matteo, Stefano Petrocchi, Eva Piano Mortari, Fabrizio De Benedetti, Fabrizio De Benedetti, Giusi Prencipe, Antonella Insalaco

Get full text

The 4th NextGen Therapies for SJIA and MAS: part 1 the elephant in the room: diagnostic/classification criteria for systemic juvenile idiopathic arthritis and adult-onset still’s d... by Peter A. Nigrovic, Fabrizio de Benedetti, Yukiko Kimura, Daniel J. Lovell, Sebastiaan J. Vastert

Get full text

Monogenic systemic lupus erythematosus onset in a 13-year-old boy with Noonan like-syndrome: a case report and literature review by Patricia Morán-Álvarez, Alessandra Gianviti, Francesca Diomedi-Camassei, Monia Ginevrino, Fabrizio de Benedetti, Claudia Bracaglia

Get full text

A child with polyarthritis and chronic lung disease: a case report of ataxia-telangiectasia by Laura De Nardi, Marco Francesco Natale, Virginia Messia, Paolo Tomà, Fabrizio De Benedetti, Antonella Insalaco

Get full text

Somatic and Abdominal Acupuncture for Pain Treatment in Adolescent Complex Regional Pain Syndrome (CRPS) of the Upper Limb: A Case Report by Giuliano Marchetti, Alessandro Vittori, Ilaria Mascilini, Elisa Francia, Antonella Insalaco, Fabrizio De Benedetti, Sergio Giuseppe Picardo

Get full text

IL-6 amplifies TLR mediated cytokine and chemokine production: implications for the pathogenesis of rheumatic inflammatory diseases. by Ivan Caiello, Gaetana Minnone, Dirk Holzinger, Thomas Vogl, Giusi Prencipe, Antonio Manzo, Fabrizio De Benedetti, Raffaele Strippoli

Get full text

Tocilizumab for massive refractory pleural effusion in an adolescent with systemic lupus erythematosus by Arianna De Matteis, Emanuela Sacco, Camilla Celani, Andrea Uva, Virginia Messia, Rebecca Nicolai, Manuela Pardeo, Fabrizio De Benedetti, Claudia Bracaglia

Get full text

Sustained Systemic Levels of IL-6 Impinge Early Muscle Growth and Induce Muscle Atrophy and Wasting in Adulthood by Laura Pelosi, Maria Grazia Berardinelli, Laura Forcina, Francesca Ascenzi, Emanuele Rizzuto, Marco Sandri, Fabrizio De Benedetti, Bianca Maria Scicchitano, Antonio Musarò

Get full text

Pro Nerve Growth Factor and Its Receptor p75NTR Activate Inflammatory Responses in Synovial Fibroblasts: A Novel Targetable Mechanism in Arthritis by Luciapia Farina, Gaetana Minnone, Stefano Alivernini, Ivan Caiello, Lucy MacDonald, Marzia Soligo, Luigi Manni, Barbara Tolusso, Simona Coppola, Erika Zara, Libenzio Adrian Conti, Angela Aquilani, Silvia Magni-Manzoni, Mariola Kurowska-Stolarska, Elisa Gremese, Fabrizio De Benedetti, Fabrizio De Benedetti, Luisa Bracci-Laudiero, Luisa Bracci-Laudiero

Get full text

Incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children: A single center experience by Martina Campisano, Camilla Celani, Alessio Franceschini, Denise Pires Marafon, Silvia Federici, Gianluca Brancaccio, Lorenzo Galletti, Fabrizio De Benedetti, Marcello Chinali, Antonella Insalaco

Get full text

An unusual presentation of purine nucleoside phosphorylase deficiency mimicking systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome by Alessia Arduini, Emiliano Marasco, Giulia Marucci, Manuela Pardeo, Antonella Insalaco, Ivan Caiello, Gian Marco Moneta, Giusi Prencipe, Fabrizio De Benedetti, Claudia Bracaglia

Get full text

Hyperactivation and altered selection of B cells in patients with paediatric Sjogren’s syndrome by Fabrizio De Benedetti, Claudia Bracaglia, Denise Pires Marafon, Ivan Caiello, Rebecca Nicolai, Alessandra Boni, Francesca Marinaro, Luciapia Farina, Rita Carsetti, Emiliano Marasco

Get full text

P101 Anti-CD19 CAR-T cell therapy for refractory childhood-onset systemic lupus erythematosus by Franco Locatelli, Claudia Bracaglia, Pietro Merli, Mattia Algeri, Rebecca Nicolai, Fabrizio de Benedetti, Emiliano Marasco, Patricia Moran Alvarez, Maria Giuseppina Cefalo, Marco Becilli

Monocytes From Patients With Macrophage Activation Syndrome and Secondary Hemophagocytic Lymphohistiocytosis Are Hyperresponsive to Interferon Gamma by Antonia Pascarella, Claudia Bracaglia, Ivan Caiello, Alessia Arduini, Gian Marco Moneta, Marianna Nicoletta Rossi, Valentina Matteo, Manuela Pardeo, Fabrizio De Benedetti, Giusi Prencipe

Get full text

Case Report: Pansclerotic Morphea-Clinical Features, Differential Diagnoses and Modern Treatment Concepts by Sarah Ventéjou, Agnes Schwieger-Briel, Rebecca Nicolai, Stephanie Christen-Zaech, Caroline Schnider, Michael Hofer, Sofia Bogiatzi, Daniel Hohl, Fabrizio De Benedetti, Marie-Anne Morren

Get full text

Assessment of disease activity using a whole-body MRI derived radiological activity index in chronic nonbacterial osteomyelitis by Martina Capponi, Denise Pires Marafon, Flaminia Rivosecchi, Yongdong Zhao, Manuela Pardeo, Virginia Messia, Laura Tanturri de Horatio, Paolo Tomà, Fabrizio De Benedetti, Antonella Insalaco

Get full text