Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil by Vicente J. Planelles-Herrero, James J. Hartman, Julien Robert-Paganin, Fady I. Malik, Anne Houdusse

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Fast skeletal muscle troponin activation increases force of mouse fast skeletal muscle and ameliorates weakness due to nebulin-deficiency. by Eun-Jeong Lee, Josine M De Winter, Danielle Buck, Jeffrey R Jasper, Fady I Malik, Siegfried Labeit, Coen A Ottenheijm, Henk Granzier

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Fast skeletal muscle troponin activator tirasemtiv increases muscle function and performance in the B6SJL-SOD1G93A ALS mouse model. by Darren T Hwee, Adam Kennedy, Julie Ryans, Alan J Russell, Zhiheng Jia, Aaron C Hinken, David J Morgans, Fady I Malik, Jeffrey R Jasper

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Effects of Aficamten on cardiac contractility in a feline translational model of hypertrophic cardiomyopathy by Ashley N. Sharpe, Maureen S. Oldach, Victor N. Rivas, Joanna L. Kaplan, Ashley L. Walker, Samantha L. Kovacs, Darren T. Hwee, Peadar Cremin, Bradley P. Morgan, Fady I. Malik, Samantha P. Harris, Joshua A. Stern

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Titin-truncating variants in hiPSC cardiomyocytes induce pathogenic proteinopathy and sarcomere defects with preserved core contractile machinery by Guanyi Huang, Anjali Bisaria, Devin L. Wakefield, Tracy M. Yamawaki, Xin Luo, Jingli A. Zhang, Patrick Vigneault, Jinghong Wang, Jeffrey D. Reagan, Oliver Oliverio, Hong Zhou, Chi-Ming Li, Olaia F. Vila, Songli Wang, Fady I. Malik, James J. Hartman, Christopher M. Hale

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