Increased Sphingosine-1-Phosphate Serum Concentrations in Subjects with Periodontitis: A Matter of Inflammation by Moritz E, Jedlitschky G, Negnal J, Tzvetkov MV, Daum G, Dörr M, Felix SB, Völzke H, Nauck M, Schwedhelm E, Meisel P, Kocher T, Rauch BH, Holtfreter B

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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure by Henry, A, Roselli, C, Lin, H, Sveinbjörnsson, G, Fatemifar, G, Hedman, AK, Wilk, JB, Morley, MP, Chaffin, MD, Helgadottir, A, Verweij, N, Dehghan, A, Almgren, P, Andersson, C, Aragam, KG, Ärnlöv, J, Backman, JD, Biggs, ML, Bloom, HL, Shah, S, Graciela E Delgado, Vilmantas Giedraitis, Brandimarto, J, Brown, MR, Buckbinder, L, Carey, DJ, Chasman, DI, Chen, X, Chen, X, Chung, J, Chutkow, W, Cook, JP, Denaxas, S, Doney, AS, Dörr, M, Dudley, SC, Dunn, ME, Engström, G, Esko, T, Felix, SB, Finan, C, Ford, I, Ghanbari, M, Ghasemi, S, Giulianini, F, Gottdiener, JS, Gross, S, Guðbjartsson, DF, Gutmann, R, Haggerty, CM

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function by Wild, PS, Felix, JF, Schillert, A, Teumer, A, Chen, M-H, Leening, MJG, Völker, U, Großmann, V, Brody, JA, Irvin, MR, Shah, SJ, Pramana, S, Lieb, W, Schmidt, R, Stanton, AV, Malzahn, D, Smith, AV, Sundström, J, Minelli, C, Ruggiero, D, Lyytikäinen, L-P, Tiller, D, Smith, JG, Monnereau, C, Di Tullio, MR, Musani, SK, Morrison, AC, Pers, TH, Morley, M, Kleber, ME, Aragam, J, Benjamin, EJ, Bis, JC, Bisping, E, Broeckel, U, Cheng, S, Deckers, JW, Del Greco M, F, Edelmann, F, Fornage, M, Franke, L, Friedrich, N, Harris, TB, Hofer, E, Hofman, A, Huang, J, Hughes, AD, Kähönen, M, investigators, KNHI, Kruppa, J, Lackner, KJ, Lannfelt, L, Laskowski, R, Launer, LJ, Leosdottir, M, Lin, H, Lindgren, CM, Loley, C, MacRae, CA, Mascalzoni, D, Mayet, J, Medenwald, D, Morris, AP, Müller, C, Müller-Nurasyid, M, Nappo, S, Nilsson, PM, Nuding, S, Nutile, T, Peters, A, Pfeufer, A, Pietzner, D, Pramstaller, PP, Raitakari, OT, Rice, KM, Rivadeneira, F, Rotter, JI, Ruohonen, ST, Sacco, RL, Samdarshi, TE, Schmidt, H, Sharp, ASP, Shields, DC, Sorice, R, Sotoodehnia, N, Stricker, BH, Surendran, P, Thom, S, Töglhofer, AM, Uitterlinden, AG, Wachter, R, Völzke, H, Ziegler, A, Münzel, T, März, W, Cappola, TP, Hirschhorn, JN, Mitchell, GF, Smith, NL, Fox, ER, Dueker, ND, Jaddoe, VWV, Melander, O, Russ, M, Lehtimäki, T, Ciullo, M, Hicks, AA, Lind, L, Gudnason, V, Pieske, B, Barron, AJ, Zweiker, R, Schunkert, H, Ingelsson, E, Liu, K, Arnett, DK, Psaty, BM, Blankenberg, S, Larson, MG, Felix, SB, Franco, OH, Zeller, T, Vasan, RS, Dörr, M

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation by Christophersen, IE, Rienstra, M, Roselli, C, Yin, X, Geelhoed, B, Barnard, J, Lin, H, Arking, DE, Smith, AV, Albert, CM, Chaffin, M, Tucker, NR, Li, M, Klarin, D, Bihlmeyer, NA, Low, SK, Weeke, PE, Müller-Nurasyid, M, Smith, JG, Brody, JA, Niemeijer, MN, Dörr, M, Trompet, S, Huffman, J, Gustafsson, S, Schurmann, C, Kleber, ME, Lyytikäinen, LP, Seppälä, I, Malik, R, Horimoto, ARVR, Perez, M, Sinisalo, J, Aeschbacher, S, Thériault, S, Yao, J, Radmanesh, F, Weiss, S, Teumer, A, Choi, SH, Weng, LC, Clauss, S, Deo, R, Rader, DJ, Shah, SH, Sun, A, Hopewell, JC, Debette, S, Chauhan, G, Yang, Q, Worrall, BB, Paré, G, Kamatani, Y, Hagemeijer, YP, Verweij, N, Siland, JE, Kubo, M, Smith, JD, Van Wagoner, DR, Bis, JC, Perz, S, Psaty, BM, Ridker, PM, Magnani, JW, Harris, TB, Launer, LJ, Shoemaker, MB, Padmanabhan, S, Haessler, J, Bartz, TM, Waldenberger, M, Lichtner, P, Arendt, M, Krieger, JE, Kähönen, M, Risch, L, Mansur, AJ, Peters, A, Smith, BH, Lind, L, Scott, SA, Lu, Y, Bottinger, EB, Hernesniemi, J, Lindgren, CM, Wong, JA, Huang, J, Eskola, M, Morris, AP, Ford, I, Reiner, AP, Delgado, G, Chen, LY, Chen, YI, Sandhu, RK, Li, M, Boerwinkle, E, Eisele, L, Lannfelt, L, Rost, N, Anderson, CD, Taylor, KD, Campbell, A, Magnusson, PK, Porteous, D, Hocking, LJ, Vlachopoulou, E, Pedersen, NL, Nikus, K, Orho-Melander, M, Hamsten, A, Heeringa, J, Denny, JC, Kriebel, J, Darbar, D, Newton-Cheh, C, Shaffer, C, Macfarlane, PW, Heilmann-Heimbach, S, Almgren, P, Huang, PL, Sotoodehnia, N, Soliman, EZ, Uitterlinden, AG, Hofman, A, Franco, OH, Völker, U, Jöckel, KH, Sinner, MF, Lin, HJ, Guo, X, METASTROKE Consortium of the ISGC, Neurology Working Group of the CHARGE Consortium, Dichgans, M, Ingelsson, E, Kooperberg, C, Melander, O, Loos, RJF, Laurikka, J, Conen, D, Rosand, J, van der Harst, P, Lokki, ML, Kathiresan, S, Pereira, A, Jukema, JW, Hayward, C, Rotter, JI, März, W, Lehtimäki, T, Stricker, BH, Chung, MK, Felix, SB, Gudnason, V, Alonso, A, Roden, DM, Kääb, S, Chasman, DI, Heckbert, SR, Benjamin, EJ, Tanaka, T, Lunetta, KL, Lubitz, SA, Ellinor, PT, AFGen Consortium

Multi-ethnic genome-wide association study for atrial fibrillation by Roselli, C, Chaffin, MD, Weng, L-C, Aeschbacher, S, Ahlberg, G, Albert, CM, Almgren, P, Alonso, A, Anderson, CD, Aragam, KG, Arking, DE, Barnard, J, Bartz, TM, Benjamin, EJ, Bihlmeyer, NA, Bis, JC, Bloom, HL, Boerwinkle, E, Bottinger, EB, Brody, JA, Calkins, H, Campbell, A, Cappola, TP, Carlquist, J, Chasman, DI, Chen, LY, Chen, Y-DI, Choi, E-K, Choi, SH, Christophersen, IE, Chung, MK, Cole, JW, Conen, D, Cook, J, Crijns, HJ, Cutler, MJ, Damrauer, SM, Daniels, BR, Darbar, D, Delgado, G, Denny, JC, Dichgans, M, Dörr, M, Dudink, EA, Dudley, SC, Esa, N, Esko, T, Eskola, M, Fatkin, D, Felix, SB, Ford, I, Franco, OH, Geelhoed, B, Grewal, RP, Gudnason, V, Guo, X, Gupta, N, Gustafsson, S, Gutmann, R, Hamsten, A, Harris, TB, Hayward, C, Heckbert, SR, Hernesniemi, J, Hocking, LJ, Hofman, A, Horimoto, ARVR, Huang, J, Huang, PL, Huffman, J, Ingelsson, E, Ipek, EG, Ito, K, Jimenez-Conde, J, Johnson, R, Jukema, JW, Kääb, S, Kähönen, M, Kamatani, Y, Kane, JP, Kastrati, A, Kathiresan, S, Katschnig-Winter, P, Kavousi, M, Kessler, T, Kietselaer, BL, Kirchhof, P, Kleber, ME, Knight, S, Krieger, JE, Kubo, M, Launer, LJ, Laurikka, J, Lehtimäki, T, Leineweber, K, Lemaitre, RN, Li, M, Lim, HE, Lin, HJ, Lin, H, Lind, L, Lindgren, CM, Lokki, M-L, London, B, Loos, RJF, Low, S-K, Lu, Y, Lyytikäinen, L-P, Macfarlane, PW, Magnusson, PK, Mahajan, A, Malik, R, Mansur, AJ, Marcus, GM, Margolin, L, Margulies, KB, März, W, McManus, DD, Melander, O, Mohanty, S, Montgomery, JA, Morley, MP, Morris, AP, Müller-Nurasyid, M, Natale, A, Nazarian, S, Neumann, B, Newton-Cheh, C, Niemeijer, MN, Nikus, K, Nilsson, P, Noordam, R, Oellers, H, Olesen, MS, Orho-Melander, M, Padmanabhan, S, Pak, H-N, Paré, G, Pedersen, NL, Pera, J, Pereira, A, Porteous, D, Psaty, BM, Pulit, SL, Pullinger, CR, Rader, DJ, Refsgaard, L, Ribasés, M, Ridker, PM, Rienstra, M, Risch, L, Roden, DM, Rosand, J, Rosenberg, MA, Rost, N, Rotter, JI, Saba, S, Sandhu, RK, Schnabel, RB, Schramm, K, Schunkert, H, Schurman, C, Scott, SA, Seppälä, I, Shaffer, C, Shah, S, Shalaby, AA, Shim, J, Shoemaker, MB, Siland, JE, Sinisalo, J, Sinner, MF, Slowik, A, Smith, AV, Smith, BH, Smith, JG, Smith, JD, Smith, NL, Soliman, EZ, Sotoodehnia, N, Stricker, BH, Sun, A, Sun, H, Svendsen, JH, Tanaka, T, Tanriverdi, K, Taylor, KD, Teder-Laving, M, Teumer, A, Thériault, S, Trompet, S, Tucker, NR, Tveit, A, Uitterlinden, AG, Van Der Harst, P, Van Gelder, IC, Van Wagoner, DR, Verweij, N, Vlachopoulou, E, Völker, U, Wang, B, Weeke, PE, Weijs, B, Weiss, R, Weiss, S, Wells, QS, Wiggins, KL, Wong, JA, Woo, D, Worrall, BB, Yang, P-S, Yao, J, Yoneda, ZT, Zeller, T, Zeng, L, Lubitz, SA, Lunetta, KL, Ellinor, PT

Genome analyses of >200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders by Ligthart, S, Vaez, A, Võsa, U, Stathopoulou, MG, De Vries, PS, Prins, BP, Van Der Most, PJ, Tanaka, T, Naderi, E, Rose, LM, Wu, Y, Karlsson, R, Barbalic, M, Lin, H, Pool, R, Zhu, G, Macé, A, Sidore, C, Trompet, S, Mangino, M, Sabater-Lleal, M, Kemp, JP, Abbasi, A, Kacprowski, T, Verweij, N, Smith, AV, Huang, T, Marzi, C, Feitosa, MF, Lohman, KK, Kleber, ME, Milaneschi, Y, Mueller, C, Huq, M, Vlachopoulou, E, Lyytikäinen, L-P, Oldmeadow, C, Deelen, J, Perola, M, Zhao, JH, Feenstra, B, Lifelines Cohort Study, Amini, M, Charge Inflammation Working Group, Lahti, J, Schraut, KE, Fornage, M, Suktitipat, B, Chen, W-M, Li, X, Nutile, T, Malerba, G, Luan, J, Bak, T, Schork, N, Del Greco M, F, Thiering, E, Mahajan, A, Marioni, RE, Mihailov, E, Eriksson, J, Ozel, AB, Zhang, W, Nethander, M, Cheng, Y-C, Aslibekyan, S, Ang, W, Gandin, I, Yengo, L, Portas, L, Kooperberg, C, Hofer, E, Rajan, KB, Schurmann, C, Hollander, W, Ahluwalia, TS, Zhao, J, Draisma, HHM, Ford, I, Timpson, N, Teumer, A, Huang, H, Wahl, S, Liu, Y, Huang, J, Uh, H-W, Geller, F, Joshi, PK, Yanek, LR, Trabetti, E, Lehne, B, Vozzi, D, Verbanck, M, Biino, G, Saba, Y, Meulenbelt, I, O'Connell, JR, Laakso, M, Giulianini, F, Magnusson, PKE, Ballantyne, CM, Hottenga, JJ, Montgomery, GW, Rivadineira, F, Rueedi, R, Steri, M, Herzig, K-H, Stott, DJ, Menni, C, Frånberg, M, St Pourcain, B, Felix, SB, Pers, TH, Bakker, SJL, Kraft, P, Peters, A, Vaidya, D, Delgado, G, Smit, JH, Großmann, V, Sinisalo, J, Seppälä, I, Williams, SR, Holliday, EG, Moed, M, Langenberg, C, Räikkönen, K, Ding, J, Campbell, H, Sale, MM, Chen, Y-DI, James, AL, Ruggiero, D, Soranzo, N, Hartman, CA, Smith, EN, Berenson, GS, Fuchsberger, C, Hernandez, D, Tiesler, CMT, Giedraitis, V, Liewald, D, Fischer, K, Mellström, D, Larsson, A, Wang, Y, Scott, WR, Lorentzon, M, Beilby, J, Ryan, KA, Pennell, CE, Vuckovic, D, Balkau, B, Concas, MP, Schmidt, R, De Leon, CF, Bottinger, EP, Kloppenburg, M, Paternoster, L, Boehnke, M, Musk, AW, Willemsen, G, Evans, DM, Madden, PAF, Kähönen, M, Kutalik, Z, Zoledziewska, M, Karhunen, V, Kritchevsky, SB, Sattar, N, Lachance, G, Clarke, R, Harris, TB, Raitakari, OT, Attia, JR, Van Heemst, D, Kajantie, E, Sorice, R, Gambaro, G, Scott, RA, Hicks, AA, Ferrucci, L, Standl, M, Lindgren, CM, Starr, JM, Karlsson, M, Lind, L, Li, JZ, Chambers, JC, Mori, TA, De Geus, EJCN, Heath, AC, Martin, NG, Auvinen, J, Buckley, BM, De Craen, AJM, Waldenberger, M, Strauch, K, Meitinger, T, Scott, RJ, McEvoy, M, Beekman, M, Bombieri, C, Ridker, PM, Mohlke, KL, Pedersen, NL, Morrison, AC, Boomsma, DI, Whitfield, JB, Strachan, DP, Hofman, A, Vollenweider, P, Cucca, F, Jarvelin, M-R, Jukema, JW, Spector, TD, Hamsten, A, Zeller, T, Uitterlinden, AG, Nauck, M, Gudnason, V, Qi, L, Grallert, H, Borecki, IB, Rotter, JI, März, W, Wild, PS, Lokki, M-L, Boyle, M, Salomaa, V, Melbye, M, Eriksson, JG, Wilson, JF, Penninx, BWJH, Becker, DM, Worrall, BB, Gibson, G, Krauss, RM, Ciullo, M, Zaza, G, Wareham, NJ, Oldehinkel, AJ, Palmer, LJ, Murray, SS, Pramstaller, PP, Bandinelli, S, Heinrich, J, Ingelsson, E, Deary, IJ, Mägi, R, Vandenput, L, Van Der Harst, P, Desch, KC, Kooner, JS, Ohlsson, C, Hayward, C, Lehtimäki, T, Shuldiner, AR, Arnett, DK, Beilin, LJ, Robino, A, Froguel, P, Pirastu, M, Jess, T, Koenig, W, Loos, RJF, Evans, DA, Schmidt, H, Smith, GD, Slagboom, PE, Eiriksdottir, G, Morris, AP, Psaty, BM, Tracy, RP, Nolte, IM, Boerwinkle, E, Visvikis-Siest, S, Reiner, AP, Gross, M, Bis, JC, Franke, L, Franco, OH, Benjamin, EJ, Chasman, DI, Dupuis, J, Snieder, H, Dehghan, A, Alizadeh, BZ

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries by Feitosa, MF, Kraja, AT, Chasman, DI, Sung, YJ, Winkler, TW, Ntalla, I, Guo, X, Franceschini, N, Cheng, C-Y, Sim, X, Vojinovic, D, Marten, J, Musani, SK, Li, C, Bentley, AR, Brown, MR, Schwander, K, Richard, MA, Noordam, R, Aschard, H, Bartz, TM, Bielak, LF, Dorajoo, R, Fisher, V, Hartwig, FP, Horimoto, ARVR, Lohman, KK, Manning, AK, Rankinen, T, Smith, AV, Tajuddin, SM, Wojczynski, MK, Alver, M, Boissel, M, Cai, Q, Campbell, A, Chai, JF, Chen, X, Divers, J, Gao, C, Goel, A, Hagemeijer, Y, Harris, SE, He, M, Hsu, F-C, Jackson, AU, Kähönen, M, Kasturiratne, A, Komulainen, P, Kühnel, B, Laguzzi, F, Luan, J, Matoba, N, Nolte, IM, Padmanabhan, S, Riaz, M, Rueedi, R, Robino, A, Said, MA, Scott, RA, Sofer, T, Stančáková, A, Takeuchi, F, Tayo, BO, Van Der Most, PJ, Varga, TV, Vitart, V, Wang, Y, Ware, EB, Warren, HR, Weiss, S, Wen, W, Yanek, LR, Zhang, W, Zhao, JH, Afaq, S, Amin, N, Amini, M, Arking, DE, Aung, T, Boerwinkle, E, Borecki, I, Broeckel, U, Brown, M, Brumat, M, Burke, GL, Canouil, M, Chakravarti, A, Charumathi, S, Chen, Y-D, Connell, JM, Correa, A, De Las Fuentes, L, De Mutsert, R, De Silva, HJ, Deng, X, Ding, J, Duan, Q, Eaton, CB, Ehret, G, Eppinga, RN, Evangelou, E, Faul, JD, Felix, SB, Forouhi, NG, Forrester, T, Franco, OH, Friedlander, Y, Gandin, I, Gao, H, Ghanbari, M, Gigante, B, Gu, CC, Gu, D, Hagenaars, SP, Hallmans, G, Harris, TB, He, J, Heikkinen, S, Heng, C-K, Hirata, M, Howard, BV, Ikram, MA, Interact Consortium, John, U, Katsuya, T, Khor, CC, Kilpeläinen, TO, Koh, W-P, Krieger, JE, Kritchevsky, SB, Kubo, M, Kuusisto, J, Lakka, TA, Langefeld, CD, Langenberg, C, Launer, LJ, Lehne, B, Lewis, CE, Li, Y, Lin, S, Liu, J, Liu, J, Loh, M, Louie, T, Mägi, R, McKenzie, CA, Meitinger, T, Metspalu, A, Milaneschi, Y, Milani, L, Mohlke, KL, Momozawa, Y, Nalls, MA, Nelson, CP, Sotoodehnia, N, Norris, JM, O'Connell, JR, Palmer, ND, Perls, T, Pedersen, NL, Peters, A, Peyser, PA, Poulter, N, Raffel, LJ, Raitakari, OT, Roll, K, Rose, LM, Rosendaal, FR, Rotter, JI, Schmidt, CO, Schreiner, PJ, Schupf, N, Scott, WR, Sever, PS, Shi, Y, Sidney, S, Sims, M, Sitlani, CM, Smith, JA, Snieder, H, Starr, JM, Strauch, K, Stringham, HM, Tan, NYQ, Tang, H, Taylor, KD, Teo, YY, Tham, YC, Turner, ST, Uitterlinden, AG, Vollenweider, P, Waldenberger, M, Wang, L, Wang, YX, Wei, WB, Williams, C, Yao, J, Yu, C, Yuan, J-M, Zhao, W, Zonderman, AB, Becker, DM, Boehnke, M, Bowden, DW, Chambers, JC, Deary, IJ, Esko, T, Farrall, M, Franks, PW, Freedman, BI, Froguel, P, Gasparini, P, Gieger, C, Jonas, JB, Kamatani, Y, Kato, N, Kooner, JS, Kutalik, Z, Laakso, M, Laurie, CC, Leander, K, Lehtimäki, T, Study, LC, Magnusson, PKE, Oldehinkel, AJ, Penninx, BWJH, Polasek, O, Porteous, DJ, Rauramaa, R, Samani, NJ, Scott, J, Shu, X-O, Van Der Harst, P, Wagenknecht, LE, Wareham, NJ, Watkins, H, Weir, DR, Wickremasinghe, AR, Wu, T, Zheng, W, Bouchard, C, Christensen, K, Evans, MK, Gudnason, V, Horta, BL, Kardia, SLR, Liu, Y, Pereira, AC, Psaty, BM, Ridker, PM, Van Dam, RM, Gauderman, WJ, Zhu, X, Mook-Kanamori, DO, Fornage, M, Rotimi, CN, Cupples, LA, Kelly, TN, Fox, ER, Hayward, C, Van Duijn, CM, Tai, ES, Wong, TY, Kooperberg, C, Palmas, W, Rice, K, Morrison, AC, Elliott, P, Caulfield, MJ, Munroe, PB, Rao, DC, Province, MA, Levy, D