Patterns of genetic differentiation and the footprints of historical migrations in the Iberian Peninsula by Bycroft, C, Fernandez-Rozadilla, C, Ruiz-Ponte, C, Quintela, I, Carracedo, A, Donnelly, P, Myers, S

Telomere length and genetics are independent colorectal tumour risk factors in an evaluation of biomarkers in normal bowel. by Fernandez-Rozadilla, C, Kartsonaki, C, Woolley, C, McClellan, M, Whittington, D, Horgan, G, Leedham, S, Kriaucionis, S, East, J, Tomlinson, I

A genome-wide association study on copy-number variation identifies a 11q11 loss as a candidate susceptibility variant for colorectal cancer by Fernandez-Rozadilla, C, Fernandez-Rozadilla, C, Cazier, J, Tomlinson, I, Tomlinson, I, Brea-Fernández, A, Lamas, M, Baiget, M, López-Fernández, L, Clofent, J, Clofent, J, Bujanda, L, Gonzalez, D, De Castro, L, Hemminki, K, Hemminki, K, Bessa, X, Andreu, M, Jover, R, Xicola, R, Llor, X, Moreno, V, Castells, A, Castellví-Bel, S, Carracedo, A

The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression. by Thomas, R, Trapani, D, Goodyer-Sait, L, Tomkova, M, Fernandez-Rozadilla, C, Sahnane, N, Woolley, C, Davis, H, Chegwidden, L, Kriaucionis, S, Maughan, T, Leedham, S, Palles, C, Furlan, D, Tomlinson, I, Lewis, A

A genome-wide association study on copy-number variation identifies a 11q11 loss as a candidate susceptibility variant for colorectal cancer. by Fernandez-Rozadilla, C, Cazier, J, Tomlinson, I, Brea-Fernández, A, Lamas, M, Baiget, M, López-Fernández, L, Clofent, J, Bujanda, L, Gonzalez, D, de Castro, L, Hemminki, K, Bessa, X, Andreu, M, Jover, R, Xicola, R, Llor, X, Moreno, V, Castells, A, Castellví-Bel, S, Carracedo, A, Ruiz-Ponte, C

A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12. by Fernandez-Rozadilla, C, Cazier, J, Tomlinson, I, Carvajal-Carmona, L, Palles, C, Lamas, M, Baiget, M, López-Fernández, L, Brea-Fernández, A, Abulí, A, Bujanda, L, Clofent, J, Gonzalez, D, Xicola, R, Andreu, M, Bessa, X, Jover, R, Llor, X, Moreno, V, Castells, A, Carracedo, Á, Castellvi-Bel, S, Ruiz-Ponte, C

A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22. by Abulí, A, Fernández-Rozadilla, C, Giráldez, MD, Muñoz, J, Gonzalo, V, Bessa, X, Bujanda, L, Reñé, J, Lanas, A, García, A, Saló, J, Argüello, L, Vilella, A, Carreño, R, Jover, R, Xicola, R, Llor, X, Carvajal-Carmona, L, Tomlinson, I, Kerr, D, Houlston, R, Piqué, J, Carracedo, A, Castells, A, Andreu, M

Pharmacogenomics in colorectal cancer: A genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration by Fernandez-Rozadilla, C, Cazier, J, Moreno, V, Crous-Bou, M, Guinó, E, Durán, G, Lamas, M, López, R, Candamio, S, Gallardo, E, Paré, L, Baiget, M, Páez, D, López-Fernández, L, Cortejoso, L, García, M, Bujanda, L, González, D, Gonzalo, V, Rodrigo, L, Reñé, J, Jover, R, Brea-Fernández, A, Andreu, M, Bessa, X

Pharmacogenomics in colorectal cancer: a genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration. by Fernandez-Rozadilla, C, Cazier, J, Moreno, V, Crous-Bou, M, Guinó, E, Durán, G, Lamas, M, López, R, Candamio, S, Gallardo, E, Paré, L, Baiget, M, Páez, D, López-Fernández, L, Cortejoso, L, García, M, Bujanda, L, González, D, Gonzalo, V, Rodrigo, L, Reñé, J, Jover, R, Brea-Fernández, A, Andreu, M, Bessa, X

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS. by Rosmarin, D, Palles, C, Pagnamenta, A, Kaur, K, Pita, G, Martin, M, Domingo, E, Jones, A, Howarth, K, Freeman-Mills, L, Johnstone, E, Wang, H, Love, S, Scudder, C, Julier, P, Fernández-Rozadilla, C, Ruiz-Ponte, C, Carracedo, A, Castellvi-Bel, S, Castells, A, Gonzalez-Neira, A, Taylor, J, Kerr, R, Kerr, D, Tomlinson, I

BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations. by Fernandez-Rozadilla, C, Palles, C, Carvajal-Carmona, L, Peterlongo, P, Nici, C, Veneroni, S, Pinheiro, M, Teixeira, MR, Moreno, V, Lamas, M, Baiget, M, Lopez-Fernandez, L, Gonzalez, D, Brea-Fernandez, A, Clofent, J, Bujanda, L, Bessa, X, Andreu, M, Xicola, R, Llor, X, Jover, R, Castells, A, Castellvi-Bel, S, Carracedo, A, Tomlinson, I

Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13 by Spain, S, Carvajal-carmona, L, Howarth, K, Jones, A, Su, Z, Cazier, J, Williams, J, Aaltonen, L, Pharoah, P, Kerr, D, Cheadle, J, Li, L, Casey, G, Vodicka, P, Sieber, O, Lipton, L, Gibbs, P, Martin, N, Montgomery, G, Young, J, Baird, P, Morreau, H, Van wezel, T, Ruiz-ponte, C, Fernandez-rozadilla, C

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS by Rosmarin, D, Palles, C, Pagnamenta, A, Kaur, K, Pita, G, Martin, M, Domingo, E, Jones, A, Howarth, K, Freeman-Mills, L, Johnstone, E, Wang, H, Love, S, Scudder, C, Julier, P, Fernández-Rozadilla, C, Ruiz-Ponte, C, Carracedo, A, Castellvi-Bel, S, Castells, A, Gonzalez-Neira, A, Taylor, J, Kerr, R, Kerr, D, Tomlinson, I

A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22 by Abulí, A, Fernández-Rozadilla, C, Giráldez, MD, Muñoz, J, Gonzalo, V, Bessa, X, Bujanda, L, Reñé, J, Lanas, A, García, A, Saló, J, Argüello, L, Vilella, A, Carreño, R, Jover, R, Xicola, R, Llor, X, Carvajal-Carmona, L, Tomlinson, I, Kerr, D, Houlston, R, Piqué, J, Carracedo, A, Castells, A, Andreu, M

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes by Chen, Z, Guo, X, Tao, R, Huyghe, JR, Law, PJ, Fernandez-Rozadilla, C, Ping, J, Jia, G, Long, J, Li, C, Shen, Q, Xie, Y, Timofeeva, MN, Thomas, M, Schmit, SL, Díez-Obrero, V, Devall, M, Moratalla-Navarro, F, Fernandez-Tajes, J, Palles, C, Sherwood, K, Briggs, SEW, Svinti, V, Donnelly, K, Kerr, R, Kerr, D, Hunter, DJ

Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13. by Spain, S, Carvajal-Carmona, L, Howarth, K, Jones, A, Su, Z, Cazier, J, Williams, J, Aaltonen, L, Pharoah, P, Kerr, D, Cheadle, J, Li, L, Casey, G, Vodicka, P, Sieber, O, Lipton, L, Gibbs, P, Martin, N, Montgomery, G, Young, J, Baird, P, Morreau, H, van Wezel, T, Ruiz-Ponte, C, Fernandez-Rozadilla, C, Carracedo, A, Castells, A, Castellvi-Bel, S, Dunlop, M, Houlston, R, Tomlinson, I

Meta-analysis of mismatch repair polymorphisms within the cogent consortium for colorectal cancer susceptibility by Picelli, S, Lorenzo Bermejo, J, Chang-Claude, J, Hoffmeister, M, Fernández-Rozadilla, C, Carracedo, A, Castells, A, Castellví-Bel, S, Naccarati, A, Pardini, B, Vodickova, L, Müller, H, Talseth-Palmer, B, Stibbard, G, Peterlongo, P, Nici, C, Veneroni, S, Li, L, Casey, G, Tenesa, A, Farrington, S, Tomlinson, I, Moreno, V, Van Wezel, T, Wijnen, J, Dunlop, M, Radice, P, Scott, R, Vodicka, P, Ruiz-Ponte, C, Brenner, H, Buch, S, Völzke, H, Hampe, J, Schafmayer, C, Lindblom, A

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. by Tomlinson, I, Carvajal-Carmona, L, Dobbins, SE, Tenesa, A, Jones, A, Howarth, K, Palles, C, Broderick, P, Jaeger, E, Farrington, S, Lewis, A, Prendergast, J, Pittman, A, Theodoratou, E, Olver, B, Walker, M, Penegar, S, Barclay, E, Whiffin, N, Martin, L, Ballereau, S, Lloyd, A, Gorman, M, Lubbe, S, Howie, B, Marchini, J, Ruiz-Ponte, C, Fernandez-Rozadilla, C, Castells, A, Carracedo, A, Castellvi-Bel, S, Duggan, D, Conti, D, Cazier, J, Campbell, H, Sieber, O, Lipton, L, Gibbs, P, Martin, N, Montgomery, G, Young, J, Baird, P, Gallinger, S, Newcomb, P, Hopper, J, Jenkins, M, Aaltonen, L, Kerr, D, Cheadle, J, Pharoah, P, Casey, G, Houlston, R, Dunlop, MG

Association analyses identify 31 new risk loci for colorectal cancer susceptibility by Law, PJ, Timofeeva, M, Fernandez-Rozadilla, C, Broderick, P, Studd, J, Fernandez-Tajes, J, Farrington, S, Svinti, V, Palles, C, Orlando, G, Sud, A, Holroyd, A, Penegar, S, Theodoratou, E, Vaughan-Shaw, P, Campbell, H, Zgaga, L, Hayward, C, Campbell, A, Harris, S, Deary, IJ, Starr, J, Gatcombe, L, Pinna, M, Briggs, S, Martin, L, Jaeger, E, Sharma-Oates, A, East, J, Leedham, S, Arnold, R, Johnstone, E, Wang, H, Kerr, D, Kerr, R, Maughan, T, Kaplan, R, Al-Tassan, N, Palin, K, Hänninen, UA, Cajuso, T, Tanskanen, T, Kondelin, J, Kaasinen, E, Sarin, A-P, Eriksson, JG, Rissanen, H, Knekt, P, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Mecklin, J-P, Buchanan, DD, Win, A-K, Hopper, J, Jenkins, ME, Lindor, NM, Newcomb, PA, Gallinger, S, Duggan, D, Casey, G, Hoffmann, P, Nöthen, MM, Jöckel, K-H, Easton, DF, Pharoah, PDP, Peto, J, Canzian, F, Swerdlow, A, Eeles, RA, Kote-Jarai, Z, Muir, K, Pashayan, N, Practical Consortium, Harkin, A, Allan, K, McQueen, J, Paul, J, Iveson, T, Saunders, M, Butterbach, K, Chang-Claude, J, Hoffmeister, M, Brenner, H, Kirac, I, Matošević, P, Hofer, P, Brezina, S, Gsur, A, Cheadle, JP, Aaltonen, LA, Tomlinson, I, Houlston, RS, Dunlop, MG