New horizons for natural killer cell research in cancer, infection and inflammation by Fernando Souza‐Fonseca‐Guimaraes

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Tumor Microenvironment-Associated Extracellular Matrix Components Regulate NK Cell Function by Gustavo Rodrigues Rossi, Edvaldo S. Trindade, Fernando Souza-Fonseca-Guimaraes

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Natural killer cells in inflammatory autoimmune diseases by Yuyan Yang, Jessica Day, Fernando Souza‐Fonseca Guimaraes, Ian P Wicks, Cynthia Louis

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Natural Killer Cells and Type 1 Innate Lymphoid Cells in Hepatocellular Carcinoma: Current Knowledge and Future Perspectives by Nicolas Jacquelot, Cyril Seillet, Fernando Souza-Fonseca-Guimaraes, Adrian G. Sacher, Gabrielle T. Belz, Pamela S. Ohashi

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Enhancing Natural Killer Cell Targeting of Pediatric Sarcoma by Natacha Omer, Natacha Omer, Natacha Omer, Wayne Nicholls, Wayne Nicholls, Bronte Ruegg, Fernando Souza-Fonseca-Guimaraes, Gustavo Rodrigues Rossi

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Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β by Lachlan P. Healy, Lachlan P. Healy, Gustavo R. Rossi, Gustavo R. Rossi, Jai Rautela, Charlotte A. Slade, Charlotte A. Slade, Charlotte A. Slade, Nicholas D. Huntington, Nicholas D. Huntington, Ingrid M. Winship, Ingrid M. Winship, Fernando Souza-Fonseca-Guimaraes, Fernando Souza-Fonseca-Guimaraes

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Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis by Cui Tu, Irina Buckle, Ingrid Leal Rojas, Gustavo Rodrigues Rossi, David P Sester, Andrew S Moore, Kristen Radford, Camille Guillerey, Fernando Souza‐Fonseca‐Guimaraes

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Editorial: Cancer Immunotherapies: From Efficacy to Resistance Mechanisms by Janin Chandra, Morten Hansen, Nathalie Labarriere, Nathalie Labarriere, Ilaria Marigo, Ilaria Marigo, Fernando Souza-Fonseca-Guimaraes, Lazar Vujanovic, Lazar Vujanovic, Yoshinobu Koguchi, Nicolas Jacquelot

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The Antitumor Effect of Heparin is not Mediated by Direct NK Cell Activation by Gustavo R. Rossi, Jenifer P. Gonçalves, Timothy McCulloch, Rebecca B. Delconte, Robert J. Hennessy, Nicholas D. Huntington, Edvaldo S. Trindade, Fernando Souza-Fonseca-Guimaraes

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GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function by Li Sun, Jai Rautela, Jai Rautela, Rebecca B. Delconte, Rebecca B. Delconte, Fernando Souza-Fonseca-Guimaraes, Fernando Souza-Fonseca-Guimaraes, Emma M. Carrington, Emma M. Carrington, Robyn L. Schenk, Robyn L. Schenk, Marco J. Herold, Marco J. Herold, Nicholas D. Huntington, Nicholas D. Huntington, Andrew M. Lew, Andrew M. Lew, Andrew M. Lew, Yuekang Xu, Yifan Zhan, Yifan Zhan, Yifan Zhan

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Type 2 Innate Lymphoid Cells Protect against Colorectal Cancer Progression and Predict Improved Patient Survival by Qiutong Huang, Nicolas Jacquelot, Adele Preaudet, Soroor Hediyeh-zadeh, Fernando Souza-Fonseca-Guimaraes, Andrew N. J. McKenzie, Philip M. Hansbro, Melissa J. Davis, Lisa A. Mielke, Tracy L. Putoczki, Gabrielle T. Belz

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Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection by Amania A. Sheikh, Lucy Cooper, Meiqi Feng, Fernando Souza-Fonseca-Guimaraes, Fanny Lafouresse, Brigette C. Duckworth, Nicholas D. Huntington, James J. Moon, Marc Pellegrini, Stephen L. Nutt, Gabrielle T. Belz, Kim L. Good-Jacobson, Joanna R. Groom

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Oncogenic drivers dictate immune control of acute myeloid leukemia by Rebecca J. Austin, Jasmin Straube, Rohit Halder, Yashaswini Janardhanan, Claudia Bruedigam, Matthew Witkowski, Leanne Cooper, Amy Porter, Matthias Braun, Fernando Souza-Fonseca-Guimaraes, Simone A. Minnie, Emily Cooper, Sebastien Jacquelin, Axia Song, Tobias Bald, Kyohei Nakamura, Geoffrey R. Hill, Iannis Aifantis, Steven W. Lane, Megan J. Bywater

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IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection. by Ismail Sebina, Kylie R James, Megan S F Soon, Lily G Fogg, Lily G Fogg, Shannon E Best, Fabian de Labastida Rivera, Marcela Montes de Oca, Fiona H Amante, Bryce S Thomas, Lynette Beattie, Fernando Souza-Fonseca-Guimaraes, Mark J Smyth, Paul J Hertzog, Geoffrey R Hill, Andreas Hutloff, Christian R Engwerda, Ashraful Haque

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NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS by Rebecca B. Delconte, Rebecca B. Delconte, Geoffrey Guittard, Wilford Goh, Wilford Goh, Soroor Hediyeh-Zadeh, Soroor Hediyeh-Zadeh, Robert J. Hennessy, Robert J. Hennessy, Jai Rautela, Jai Rautela, Melissa J. Davis, Melissa J. Davis, Fernando Souza-Fonseca-Guimaraes, Jacques A. Nunès, Nicholas D. Huntington, Nicholas D. Huntington, Nicholas D. Huntington, Nicholas D. Huntington

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Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression by Stefano Mangiola, Patrick McCoy, Martin Modrak, Fernando Souza-Fonseca-Guimaraes, Daniel Blashki, Ryan Stuchbery, Simon P. Keam, Michael Kerger, Ken Chow, Chayanica Nasa, Melanie Le Page, Natalie Lister, Simon Monard, Justin Peters, Phil Dundee, Scott G. Williams, Anthony J. Costello, Paul J. Neeson, Bhupinder Pal, Nicholas D. Huntington, Niall M. Corcoran, Anthony T. Papenfuss, Christopher M. Hovens

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In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection by Chin Wee Tan, Jinjin Chen, Ning Liu, Dharmesh D. Bhuva, Tony Blick, James Monkman, Caroline Cooper, Malvika Kharbanda, Kristen Feher, Belinda Phipson, Emily E. Killingbeck, Liuliu Pan, Youngmi Kim, Yan Liang, Andy Nam, Michael Leon, Paulo Souza-Fonseca-Guimaraes, Seigo Nagashima, Ana Paula Camargo Martins, Cleber Machado-Souza, Lucia de Noronha, Benjamin Tang, Kirsty Short, John Fraser, Gabrielle T. Belz, Fernando Souza-Fonseca-Guimaraes, Arutha Kulasinghe, Melissa J. Davis

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Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer by Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio

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Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures by Nataly Stylianou, Ismail Sebina, Nicholas Matigian, James Monkman, Hadeel Doehler, Joan Röhl, Mark Allenby, Andy Nam, Liuliu Pan, Anja Rockstroh, Habib Sadeghirad, Kimberly Chung, Thais Sobanski, Ken O'Byrne, Ana Clara Simoes Florido Almeida, Patricia Zadorosnei Rebutini, Cleber Machado‐Souza, Emanuele Therezinha Schueda Stonoga, Majid E Warkiani, Carlos Salomon, Kirsty Short, Lana McClements, Lucia deNoronha, Ruby Huang, Gabrielle T Belz, Fernando Souza‐Fonseca‐Guimaraes, Vicki Clifton, Arutha Kulasinghe

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NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease by Hazel Tye, Chien-Hsiung Yu, Lisa A. Simms, Marcel R. de Zoete, Man Lyang Kim, Martha Zakrzewski, Jocelyn S. Penington, Cassandra R. Harapas, Fernando Souza-Fonseca-Guimaraes, Leesa F. Wockner, Adele Preaudet, Lisa A. Mielke, Stephen A. Wilcox, Yasunori Ogura, Sinead C. Corr, Komal Kanojia, Konstantinos A. Kouremenos, David P. De Souza, Malcolm J. McConville, Richard A. Flavell, Motti Gerlic, Benjamin T. Kile, Anthony T. Papenfuss, Tracy L. Putoczki, Graham L. Radford-Smith, Seth L. Masters

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