Quinazolinone-based anticancer agents: synthesis, anti-proliferative SAR, anti-tubulin activity and tubulin co-crystal structure by Dohle, W, Jourdan, F, Menchon, G, Prota, A, Foster, P, Mannion, P, Hamel, E, Thomas, M, Kasprzyk, P, Ferrandis, E, Steinmetz, M, Leese, M, Potter, B