FinnGen

The FinnGen project was launched in 2017 with the aim of collecting biological samples from 500,000 participants in Finland over six years with the aim of improving health through genetic research. This is about 10% of the population. It is hoped that it will be a springboard for better diagnostics and new therapies. It is the key to Finland's Health Sector Growth Strategy for Research and Innovation Activities. __TOC__ Provided by Wikipedia
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  1. 1
    Disentangling the link between maternal influences on birth weight and disease risk in 36,211 genotyped mother–child pairs

    Disentangling the link between maternal influences on birth weight and disease risk in 36,211 genotyped mother–child pairs by Jaakko T. Leinonen, FinnGen, Matti Pirinen, Taru Tukiainen

    Published 2024-02-01
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  2. 2
    Narcolepsy as a potential risk factor for Schizophrenia

    Narcolepsy as a potential risk factor for Schizophrenia by Reyhane Eghtedarian, Anniina M. Tervi, Samuel E. Jones, FinnGen, Markku Partinen, Essi Viippola, Hanna M. Ollila

    Published 2025-02-01
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  3. 3
    Causal relationship between gut microbiota and immune thrombocytopenia: a Mendelian randomization study of two samples

    Causal relationship between gut microbiota and immune thrombocytopenia: a Mendelian randomization study of two samples by Dongmei Guo, Dongmei Guo, Qian Chen, Qian Chen, Guojun Wang, Guojun Wang, ChunPu Li, ChunPu Li, FinnGen consortium

    Published 2023-11-01
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  4. 4
    Use of electronic health record data mining for heart failure subtyping

    Use of electronic health record data mining for heart failure subtyping by Matti A. Vuori, Tuomo Kiiskinen, Niina Pitkänen, Samu Kurki, Hannele Laivuori, Tarja Laitinen, Sampo Mäntylahti, Aarno Palotie, FinnGen, Teemu J. Niiranen

    Published 2023-09-01
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  5. 5
    Genome-wide association analysis of plasma lipidome identifies 495 genetic associations

    Genome-wide association analysis of plasma lipidome identifies 495 genetic associations by Linda Ottensmann, Rubina Tabassum, Sanni E. Ruotsalainen, Mathias J. Gerl, Christian Klose, Elisabeth Widén, FinnGen, Kai Simons, Samuli Ripatti, Matti Pirinen

    Published 2023-10-01
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  6. 6
    Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects

    Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects by Martin Broberg, Minna Ampuja, Samuel Jones, Tiina Ojala, Otto Rahkonen, Riikka Kivelä, James Priest, FinnGen, Aarno Palotie, Hanna M. Ollila, Emmi Helle

    Published 2024-03-01
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  7. 7
    Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events

    Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events by Henrike O. Heyne, Fanny-Dhelia Pajuste, Julian Wanner, Jennifer I. Daniel Onwuchekwa, Reedik Mägi, Aarno Palotie, FinnGen, Estonian Biobank research team, Reetta Kälviainen, Mark J. Daly

    Published 2024-07-01
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  8. 8
    Leveraging large-scale multi-omics evidences to identify therapeutic targets from genome-wide association studies

    Leveraging large-scale multi-omics evidences to identify therapeutic targets from genome-wide association studies by Samuel Lessard, Michael Chao, Kadri Reis, FinnGen, Estonian Biobank Research Team, Mathieu Beauvais, Deepak K. Rajpal, Jennifer Sloane, Priit Palta, Katherine Klinger, Emanuele de Rinaldis, Khader Shameer, Clément Chatelain

    Published 2024-11-01
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  9. 9
    Genome-wide meta-analysis conducted in three large biobanks expands the genetic landscape of lumbar disc herniations

    Genome-wide meta-analysis conducted in three large biobanks expands the genetic landscape of lumbar disc herniations by Ville Salo, Juhani Määttä, Eeva Sliz, FinnGen, Ene Reimann, Reedik Mägi, Estonian Biobank Research Team, Kadri Reis, Abdelrahman G. Elhanas, Anu Reigo, Priit Palta, Tõnu Esko, Jaro Karppinen, Johannes Kettunen

    Published 2024-11-01
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  10. 10
    Meta-analysis of genome-wide association studies of gestational duration and spontaneous preterm birth identifies new maternal risk loci.

    Meta-analysis of genome-wide association studies of gestational duration and spontaneous preterm birth identifies new maternal risk loci. by Anu Pasanen, Minna K Karjalainen, FinnGen, Ge Zhang, Heli Tiensuu, Antti M Haapalainen, Marja Ojaniemi, Bjarke Feenstra, Bo Jacobsson, Aarno Palotie, Hannele Laivuori, Louis J Muglia, Mika Rämet, Mikko Hallman

    Published 2023-10-01
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  11. 11
    Socio-demographic and genetic risk factors for drug adherence and persistence across 5 common medication classes

    Socio-demographic and genetic risk factors for drug adherence and persistence across 5 common medication classes by Mattia Cordioli, Andrea Corbetta, Hanna Maria Kariis, Sakari Jukarainen, Pekka Vartiainen, Tuomo Kiiskinen, Matteo Ferro, FinnGen, Estonian Biobank Research Team, Markus Perola, Mikko Niemi, Samuli Ripatti, Kelli Lehto, Lili Milani, Andrea Ganna

    Published 2024-10-01
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  12. 12
    NTHL1 is a recessive cancer susceptibility gene

    NTHL1 is a recessive cancer susceptibility gene by Anna K. Nurmi, Liisa M. Pelttari, Johanna I. Kiiski, Sofia Khan, Mika Nurmikolu, Maija Suvanto, Niina Aho, Tiina Tasmuth, Eija Kalso, Johanna Schleutker, Anne Kallioniemi, Päivi Heikkilä, FinnGen, Kristiina Aittomäki, Carl Blomqvist, Heli Nevanlinna

    Published 2023-11-01
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  13. 13
    Deep learning of left atrial structure and function provides link to atrial fibrillation risk

    Deep learning of left atrial structure and function provides link to atrial fibrillation risk by James P. Pirruccello, Paolo Di Achille, Seung Hoan Choi, Joel T. Rämö, Shaan Khurshid, Mahan Nekoui, Sean J. Jurgens, Victor Nauffal, Shinwan Kany, FinnGen, Kenney Ng, Samuel F. Friedman, Puneet Batra, Kathryn L. Lunetta, Aarno Palotie, Anthony A. Philippakis, Jennifer E. Ho, Steven A. Lubitz, Patrick T. Ellinor

    Published 2024-05-01
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  14. 14
    A FinnGen pilot clinical recall study for Alzheimer’s disease

    A FinnGen pilot clinical recall study for Alzheimer’s disease by Valtteri Julkunen, Claudia Schwarz, Juho Kalapudas, Merja Hallikainen, Aino-Kaisa Piironen, Arto Mannermaa, Hanna Kujala, Timo Laitinen, Veli-Matti Kosma, Teemu I. Paajanen, Reetta Kälviäinen, Mikko Hiltunen, Sanna-Kaisa Herukka, Sari Kärkkäinen, Tarja Kokkola, Mia Urjansson, FinnGen, Markus Perola, Aarno Palotie, Eero Vuoksimaa, Heiko Runz

    Published 2023-08-01
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  15. 15
    Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis

    Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis by Pavel Loginovic, Feiyi Wang, Jiang Li, Lauric Ferrat, Uyenlinh L. Mirshahi, H. Shanker Rao, Axel Petzold, Jessica Tyrrell, Harry D. Green, Michael N. Weedon, Andrea Ganna, Tiinamaija Tuomi, David J. Carey, UKBB Eye & Vision Consortium, FinnGen, Geisinger-Regeneron DiscovEHR Collaboration, Richard A. Oram, Tasanee Braithwaite

    Published 2024-02-01
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  16. 16
    SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease

    SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease by Satu Strausz, Erik Abner, Grace Blacker, Sarah Galloway, Paige Hansen, Qingying Feng, Brandon T. Lee, Samuel E. Jones, Hele Haapaniemi, Sten Raak, George Ronald Nahass, Erin Sanders, FinnGen, Estonian Genome Centre, Estonian Biobank Research Team, Pilleriin Soodla, Urmo Võsa, Tõnu Esko, Nasa Sinnott-Armstrong, Irving L. Weissman, Mark Daly, Tuomas Aivelo, Michal Caspi Tal, Hanna M. Ollila

    Published 2024-03-01
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  17. 17
    Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry

    Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry by Kharis Burns, Benjamin H. Mullin, Loes M. E. Moolhuijsen, Triin Laisk, Jaakko S. Tyrmi, Jinrui Cui, Ky’Era V. Actkins, Yvonne V. Louwers, Estonian Biobank Research Team, Lea K. Davis, Frank Dudbridge, Ricardo Azziz, Mark O. Goodarzi, Hannele Laivuori, Reedik Mägi, Jenny A. Visser, Joop S. E. Laven, Scott G. Wilson, FinnGen, International PCOS Consortium, Felix R. Day, Bronwyn G. A. Stuckey

    Published 2024-02-01
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  18. 18
    High incidence and geographic distribution of cleft palate in Finland are associated with the IRF6 gene

    High incidence and geographic distribution of cleft palate in Finland are associated with the IRF6 gene by Fedik Rahimov, Pekka Nieminen, Priyanka Kumari, Emma Juuri, Tiit Nikopensius, Kitt Paraiso, Jakob German, Antti Karvanen, Mart Kals, Abdelrahman G. Elnahas, Juha Karjalainen, Mitja Kurki, Aarno Palotie, FinnGen, Estonian Biobank Research Team, Arja Heliövaara, Tõnu Esko, Sakari Jukarainen, Priit Palta, Andrea Ganna, Anjali P. Patni, Daniel Mar, Karol Bomsztyk, Julie Mathieu, Hannele Ruohola-Baker, Axel Visel, Walid D. Fakhouri, Brian C. Schutte, Robert A. Cornell, David P. Rice

    Published 2024-11-01
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  19. 19
    A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk

    A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk by Bradley Jermy, Kristi Läll, Brooke N. Wolford, Ying Wang, Kristina Zguro, Yipeng Cheng, Masahiro Kanai, Stavroula Kanoni, Zhiyu Yang, Tuomo Hartonen, Remo Monti, Julian Wanner, Omar Youssef, Estonian Biobank research team, FinnGen, Christoph Lippert, David van Heel, Yukinori Okada, Daniel L. McCartney, Caroline Hayward, Riccardo E. Marioni, Simone Furini, Alessandra Renieri, Alicia R. Martin, Benjamin M. Neale, Kristian Hveem, Reedik Mägi, Aarno Palotie, Henrike Heyne, Nina Mars, Andrea Ganna, Samuli Ripatti

    Published 2024-06-01
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  20. 20
    Low prevalence of CWH43 variants among Finnish and Norwegian idiopathic normal pressure hydrocephalus patients: a cohort-based observational study

    Low prevalence of CWH43 variants among Finnish and Norwegian idiopathic normal pressure hydrocephalus patients: a cohort-based observational study by Joel Räsänen, Seppo Helisalmi, Sami Heikkinen, Joose Raivo, Ville E. Korhonen, Henna Martiskainen, Antti Junkkari, Benjamin Grenier-Boley, Céline Bellenguez, Minna Oinas, Cecilia Avellan, Janek Frantzen, Anna Kotkansalo, Jaakko Rinne, Antti Ronkainen, Mikko Kauppinen, Mikael von und zu Fraunberg, Kimmo Lönnrot, Jarno Satopää, Markus Perola, Anne M. Koivisto, Valtteri Julkunen, Anne M. Portaankorva, Arto Mannermaa, Hilkka Soininen, Juha E. Jääskeläinen, Jean-Charles Lambert, Per K. Eide, FinnGen, Aarno Palotie, Mitja I. Kurki, Mikko Hiltunen, Ville Leinonen, Anssi Lipponen

    Published 2025-02-01
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