New challenges in endpoints for drug development in advanced melanoma. by Ribas, A, Hersey, P, Middleton, MR, Gogas, H, Flaherty, K, Sondak, V, Kirkwood, J

Phase I study of GW572016 (lapatinib), a dual kinase inhibitor, in combination with irinotecan (IR), 5-fluorouracil (FU) and leucovorin (LV). by Midgley, R, Flaherty, K, Haller, D, Versola, M, Smith, D, Koch, K, Pandite, L, Kerr, D, O'Dwyer, P, Middleton, MR

Quantification of the dynamics of antibody response to malaria to inform sero-surveillance in pregnant women by Dharmaratne, ADVTT, Dini, S, O'Flaherty, K, Price, DJ, Beeson, J, McGready, R, Nosten, F, Fowkes, FJI, Simpson, JA, Zaloumis, SG

A phase I and pharmacokinetic study of lapatinib in combination with infusional 5-fluorouracil, leucovorin and irinotecan. by Midgley, R, Kerr, D, Flaherty, K, Stevenson, J, Pratap, SE, Koch, K, Smith, D, Versola, M, Fleming, R, Ward, C, O'Dwyer, P, Middleton, MR

The contribution of functional antimalarial immunity to measures of parasite clearance in therapeutic efficacy studies of artemisinin derivatives by O'Flaherty, K, Ataíde, R, Zaloumis, S, Ashley, E, Powell, R, Feng, G, Reiling, L, Dondorp, A, Day, N, Dhorda, M, Fairhurst, R, Lim, P, Amaratunga, C, Pukrittayakamee, S, Hien, T, Htut, Y, Mayxay, M, Faiz, M, Beeson, J, Nosten, F, Simpson, J, White, N, Fowkes, F

Host immunity and the assessment of emerging artemisinin resistance in a multinational cohort by Ataide, R, Ashley, E, Powell, R, Chan, J, Malloy, M, O'Flaherty, K, Takashima, E, Langer, C, Tsuboi, T, Dondorp, A, Day, N, Dhorda, M, Fairhurst, R, Lim, P, Amaratunga, C, Pukrittayakamee, S, Hien, T, Htut, Y, Mayxay, M, Faiz, M, Beeson, J, Nosten, F, Simpson, J, White, N, Fowkes, F

Improved survival with MEK inhibition in BRAF-mutated melanoma. by Flaherty, K, Robert, C, Hersey, P, Nathan, P, Garbe, C, Milhem, M, Demidov, L, Hassel, J, Rutkowski, P, Mohr, P, Dummer, R, Trefzer, U, Larkin, J, Utikal, J, Dreno, B, Nyakas, M, Middleton, M, Becker, J, Casey, M, Sherman, L, Wu, F, Ouellet, D, Martin, A, Patel, K, Schadendorf, D

Systematic identification of signaling pathways with potential to confer anticancer drug resistance by Martz, C. A., Ottina, Kathleen, Singleton, K. R., Jasper, J. S., Wardell, S. E., Peraza-Penton, A., Anderson, G. R., Winter, P. S., Alley, H. M., Kwong, L. N., Cooper, Z. A., Tetzlaff, M., Chen, P.-L., Rathmell, J. C., Flaherty, K. T., Wargo, J. A., McDonnell, D. P., Wood, K. C., Wang, Tim, Sabatini, David

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Comparison of antibody responses and parasite clearance in artemisinin therapeutic efficacy studies in Democratic Republic of Congo and Asia by Cutts, JC, O'Flaherty, K, Zaloumis, SG, Ashley, EA, Chan, JA, Onyamboko, MA, Fanello, C, Dondorp, AM, Day, NP, Phyo, AP, Dhorda, M, Imwong, M, Fairhurst, RM, Lim, P, Amaratunga, C, Pukrittayakamee, S, Hien, TT, Htut, Y, Mayxay, M, Abdul Faiz, M, Takashima, E, Tsuboi, T, Beeson, JG, Nosten, F, Simpson, JA, White, NJ, Fowkes, FJI

Anti-gametocyte antigen humoral immunity and gametocytemia during treatment of uncomplicated falciparum malaria: a multi-national study by O'Flaherty, K, Chan, J-A, Cutts, JC, Zaloumis, SG, Ashley, EA, Phyo, AP, Drew, DR, Dondorp, AM, Day, NP, Dhorda, M, Fairhurst, RM, Lim, P, Amaratunga, C, Pukrittayakamee, S, Hien, TT, Htut, Y, Mayxay, M, Faiz, MA, Mokuolu, OA, Onyamboko, MA, Fanello, C, Takashima, E, Tsuboi, T, Theisen, M, Nosten, F, Beeson, JG, Simpson, JA, White, NJ, Fowkes, FJI

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq by Tirosh, I., Izar, B., Treacy, D., Trombetta, J. J., Rotem, A., Rodman, C., Lian, C., Murphy, G., Fallahi-Sichani, M., Dutton-Regester, K., Lin, J.-R., Cohen, O., Shah, P., Lu, D., Villani, A.-C., Andreev, A. Y., Van Allen, E. M., Bertagnolli, M., Sorger, P. K., Sullivan, R. J., Flaherty, K. T., Frederick, D. T., Jane-Valbuena, J., Rozenblatt-Rosen, O., Prakadan, Sanjay, Wadsworth, Marc Havens, Genshaft, Alex S., Hughes, Travis K., Ziegler, Carly, Kazer, Samuel Weisgurt, Gaillard de Saint Germain, Alethe, Kolb, Kellie Elizabeth, Johannessen, Cory M., Yoon, Clifford H., Shalek, Alexander K, Regev, Aviv, Garraway, Levi A.

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