Showing 1 - 13 results of 13 for search 'Flaherty, L', query time: 0.02s
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Comparative bioenergetic assessment of transformed cells using a cell energy budget platform. by Zhdanov, A, Favre, C, O'Flaherty, L, Adam, J, O'Connor, R, Pollard, P, Papkovsky, D
Published 2011Journal article -
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MHC class I gene organization in > 1.5-Mb YAC contigs from the H2-M region. by Jones, E, Xiao, H, Schultz, R, Flaherty, L, Trachtulec, Z, Vincek, V, Larin, Z, Lehrach, H, Lindahl, K
Published 1995Journal article -
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Cells lacking the fumarase tumor suppressor are protected from apoptosis through a hypoxia-inducible factor-independent, AMPK-dependent mechanism. by Bardella, C, Olivero, M, Lorenzato, A, Geuna, M, Adam, J, O'Flaherty, L, Rustin, P, Tomlinson, I, Pollard, P, Di Renzo, M
Published 2012Journal article -
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Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1(Alpha) (HIF-1(Alpha)). by Thalhammer, A, Bencokova, Z, Poole, R, Loenarz, C, Adam, J, O'Flaherty, L, Schodel, J, Mole, D, Giaslakiotis, K, Schofield, C, Hammond, E, Ratcliffe, P, Pollard, P
Published 2011Journal article -
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Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism. by O'Flaherty, L, Adam, J, Heather, L, Zhdanov, A, Chung, Y, Miranda, M, Croft, J, Olpin, S, Clarke, K, Pugh, C, Griffiths, J, Papkovsky, D, Ashrafian, H, Ratcliffe, P, Pollard, P
Published 2010Journal article -
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Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency by Ternette, N, Fischer, R, Kessler, B, Yang, M, Laroyia, M, O'Flaherty, L, Wolhulter, K, Adam, J, Pollard, P, Lappin, T, Kitagawa, M, Igarashi, K, Saito, K, Kato, K, Soga, T, Berquand, A, Frizzell, N
Published 2013Journal article -
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Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency. by Ternette, N, Yang, M, Laroyia, M, Kitagawa, M, O'Flaherty, L, Wolhulter, K, Igarashi, K, Saito, K, Kato, K, Fischer, R, Berquand, A, Kessler, B, Lappin, T, Frizzell, N, Soga, T, Adam, J, Pollard, P
Published 2013Journal article -
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Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. by Adam, J, Hatipoglu, E, O'Flaherty, L, Ternette, N, Sahgal, N, Lockstone, H, Baban, D, Nye, E, Stamp, G, Wolhuter, K, Stevens, M, Fischer, R, Carmeliet, P, Maxwell, P, Pugh, C, Frizzell, N, Soga, T, Kessler, B, El-Bahrawy, M, Ratcliffe, P, Pollard, P
Published 2011Journal article -
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A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia. by Adam, J, Yang, M, Bauerschmidt, C, Kitagawa, M, O'Flaherty, L, Maheswaran, P, Özkan, G, Sahgal, N, Baban, D, Kato, K, Saito, K, Iino, K, Igarashi, K, Stratford, M, Pugh, C, Tennant, D, Ludwig, C, Davies, B, Ratcliffe, P, El-Bahrawy, M, Ashrafian, H, Soga, T, Pollard, P
Published 2013Journal article -
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Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. by Bardella, C, El-Bahrawy, M, Frizzell, N, Adam, J, Ternette, N, Hatipoglu, E, Howarth, K, O'Flaherty, L, Roberts, I, Turner, G, Taylor, J, Giaslakiotis, K, Macaulay, V, Harris, A, Chandra, A, Lehtonen, H, Launonen, V, Aaltonen, L, Pugh, C, Mihai, R, Trudgian, D, Kessler, B, Baynes, J, Ratcliffe, P, Tomlinson, I
Published 2011Journal article -
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Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis. by Ashrafian, H, O'Flaherty, L, Adam, J, Steeples, V, Chung, Y, East, P, Vanharanta, S, Lehtonen, H, Nye, E, Hatipoglu, E, Miranda, M, Howarth, K, Shukla, D, Troy, H, Griffiths, J, Spencer-Dene, B, Yusuf, M, Volpi, E, Maxwell, P, Stamp, G, Poulsom, R, Pugh, C, Costa, B, Bardella, C, Di Renzo, M
Published 2010Journal article -
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Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. by Bardella, C, El-Bahrawy, M, Frizzell, N, Adam, J, Ternette, N, Hatipoglu, E, Howarth, K, O'Flaherty, L, Roberts, I, Turner, G, Taylor, J, Giaslakiotis, K, Macaulay, V, Harris, A, Chandra, A, Lehtonen, H, Launonen, V, Aaltonen, L, Pugh, C, Mihai, R, Trudgian, D, Kessler, B, Baynes, J, Ratcliffe, P, Tomlinson, I, Pollard, P
Published 2011Journal article