Towards the chemometric dissection of peptide--HLA-A*0201 binding affinity: comparison of local and global QSAR models. door Doytchinova, I, Walshe, V, Borrow, P, Flower, DR

Analysis of peptide-protein binding using amino acid descriptors: prediction and experimental verification for human histocompatibility complex HLA-A0201. door Guan, P, Doytchinova, I, Walshe, V, Borrow, P, Flower, DR

Coupling in silico and in vitro analysis of peptide-MHC binding: a bioinformatic approach enabling prediction of superbinding peptides and anchorless epitopes. door Doytchinova, I, Walshe, V, Jones, N, Gloster, SE, Borrow, P, Flower, DR

A deletion in the gene encoding the CD45 antigen in a patient with SCID. door Tchilian, E, Wallace, D, Wells, R, Flower, DR, Morgan, G, Beverley, P

A deletion in the gene encoding the CD45 antigen in a patient with SCID door Tchilian, E, Wallace, D, Wells, R, Flower, DR, Morgan, G, Beverley, P

Novel perforin mutation in a patient with hemophagocytic lymphohistiocytosis and CD45 abnormal splicing. door McCormick, J, Flower, DR, Strobel, S, Wallace, D, Beverley, P, Tchilian, E

Novel perforin mutation in a patient with hemophagocytic lymphohistiocytosis and CD45 abnormal splicing door McCormick, J, Flower, DR, Strobel, S, Wallace, D, Beverley, P, Tchilian, E

Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection. door Brown, R, Juttla, V, Tarr, A, Finnis, R, Irving, W, Hemsley, S, Flower, DR, Borrow, P, Ball, J

Empirical, AI, and QSAR approaches to peptide-MHC binding prediction door Hattotuwagama, C, Guan, P, Davies, M, Taylor, D, Walshe, V, Hemsley, S, Toseland, C, Doytchinova, I, Borrow, P, Flower, DR

Toward the discovery of vaccine adjuvants: coupling in silico screening and in vitro analysis of antagonist binding to human and mouse CCR4 receptors. door Davies, M, Bayry, J, Tchilian, E, Vani, J, Shaila, MS, Forbes, E, Draper, S, Beverley, P, Tough, D, Flower, DR

Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response. door Jones, N, Wei, X, Flower, DR, Wong, M, Michor, F, Saag, MS, Hahn, B, Nowak, M, Shaw, G, Borrow, P

In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination. door Bayry, J, Tchilian, E, Davies, M, Forbes, E, Draper, S, Kaveri, S, Hill, A, Kazatchkine, MD, Beverley, P, Flower, DR, Tough, D

MHC class I bound to an immunodominant Theileria parva epitope demonstrates unconventional presentation to T cell receptors. door Macdonald, I, Harkiolaki, M, Hunt, L, Connelley, T, Carroll, A, MacHugh, N, Graham, S, Jones, E, Morrison, W, Flower, DR, Ellis, SA

Computational vaccinology: quantitative approaches. door Flower, DR, McSparron, H, Blythe, M, Zygouri, C, Taylor, D, Guan, P, Wan, S, Coveney, P, Walshe, V, Borrow, P, Doytchinova, I

Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes. door Walshe, V, Hattotuwagama, C, Doytchinova, I, Wong, M, Macdonald, I, Mulder, A, Claas, F, Pellegrino, P, Turner, J, Williams, I, Turnbull, E, Borrow, P, Flower, DR

Computational Chemistry, Informatics, and the Discovery of Vaccines door Guan, P, Davies, M, Taylor, D, Wan, S, McSparron, H, Hemsley, S, Toseland, C, Blythe, M, Taylor, P, Walshe, V, Hattotuwagama, C, Doytchinova, I, Coveney, P, Borrow, P, Flower, DR

Greater CD8+ TCR heterogeneity and functional flexibility in HIV-2 compared to HIV-1 infection. door Lopes, A, Jaye, A, Dorrell, L, Sabally, S, Alabi, A, Jones, N, Flower, DR, De Groot, A, Newton, P, Lascar, R, Williams, I, Whittle, H, Bertoletti, A, Borrow, P, Maini, M