Preferential targeting of co-evolving Gag residues in long-term non progressors by Sunshine J, Shekhar K, Heckerman D, Chakraborty AK, Frahm N

Effective Antiviral CD8+T Cells Responses Are Rare in HIVPositive Step and Phambili Study Participants but Are Targeted to Low Entropy Viral Epitopes by Hancock, G, Yang, H, Mcmichael, A, Frahm, N, McElrath, J, Dorrell, L

P08-06 LB. A genome-wide association study of host genetic determinants of T cell responses to the MRKAd5 HIV-1 gag/pol/nef vaccine in the STEP trial by Frahm N, Geraghty DE, Casimiro DR, McElrath J, Cirulli ET, Shianna KV, Fellay J, Goldstein DB

rAd5 prime/NYVAC-B boost regimen is superior to NYVAC-B prime/rAd5 boost regimen for both response rates and magnitude of CD4 and CD8 T-cell responses by Bart P, Huang Y, Frahm N, Karuna S, Allen M, Kochar NK, Chappuis S, Gaillard J, Graham B, Pantaleo G

The HIVconsv Vaccines Induce Polyfunctional and Highly Proliferative T Cells that Control In Vitro HIV Replication: HIV-CORE002 Phase-I Clinical Trial by Ondondo, B, Ahmed, T, Nicola, B, Hayton, E, Vasilyeva, E, Frahm, N, Colloca, S, Nicosia, A, McMichael, A, Dorrell, L, Hanke, T

Lower viral loads and slower CD4 decline in MRKAd5 HIV-1 vaccinees expressing disease-susceptible HLA-B*58:02 by Leitman, E, Hurst, J, Mori, M, Kublin, J, Ndung'u, T, Walker, B, Carlson, J, Gray, G, Matthews, P, Frahm, N, Goulder, P

First-in-human phase I clinical trial of a recombinant vesicular stomatitis virus (rVSV)-based preventive HIV-1 vaccine by Fuchs JD, Frank I, Kochar N, Elizaga M, Allen M, Carter D, Frahm N, Kalams SA, Mulligan M, Sheets R, Pensiero M, Clarke D, Eldridge J

Immunogenicity of a universal HIV-1 vaccine vectored by DNA, MVA and CHADV-63 in a Phase I/IIA clinical trial by Borthwick NJ, Ahmed T, Rose A, Ebrahimsa U, Black A, Hayton E, Yang H, Hancock G, Campion S, Frahm N, Colloca S, Nicosia A, McMichael A, Dorrell L, Hanke T

Immunogenicity of a universal HIV-1 vaccine vectored by DNA, MVA and CHADV-63 in a Phase I/IIA clinical trial by Borthwick, N, Ahmed, T, Rose, A, Ebrahimsa, U, Black, A, Hayton, E, Yang, H, Hancock, G, Campion, S, Frahm, N, Colloca, S, Nicosia, A, McMichael, A, Dorrell, L, Hanke, T

Combined Clinical and Immunological Biomarkers Predict Rates of CD4 Decline in Chronic Untreated HIV Infection by Brumme, Z, Nair, K, Wang, B, van der Stok, M, Brumme, C, Bishop, K, Reddy, S, Mncube, Z, Chonco, F, Frahm, N, Goulder, P, Ndung'u, T, Freedberg, K, Losina, E, Walker, B

Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial by Campion, SL, Brenna, E, Thomson, E, Fischer, W, Ladell, K, McLaren, JE, Price, DA, Frahm, N, McElrath, JM, Cohen, KW, Maenza, JR, Walsh, SR, Baden, LR, Haynes, BF, Korber, B, Borrow, P, McMichael, AJ

Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses by Hancock, G, Yang, H, Yorke, E, Wainwright, E, Bourne, V, Frisbee, A, Payne, T, Berrong, M, Ferrari, G, Chopera, D, Hanke, T, Mothe, B, Brander, C, McElrath, M, McMichael, A, Goonetilleke, N, Tomaras, G, Frahm, N, Dorrell, L

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1 by Borthwick, N, Ahmed, T, Ondondo, B, Hayes, P, Rose, A, Ebrahimsa, U, Hayton, E, Black, A, Bridgeman, A, Rosario, M, Hill, A, Berrie, E, Moyle, S, Frahm, N, Cox, J, Colloca, S, Nicosia, A, Gilmour, J, Mcmichael, A, Dorrell, L, Hanke, T

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1. by Borthwick, N, Ahmed, T, Ondondo, B, Hayes, P, Rose, A, Ebrahimsa, U, Hayton, E, Black, A, Bridgeman, A, Rosario, M, Hill, A, Berrie, E, Moyle, S, Frahm, N, Cox, J, Colloca, S, Nicosia, A, Gilmour, J, McMichael, A, Dorrell, L, Hanke, T

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-... by Altfeld, M, Allen, T, Kalife, E, Frahm, N, Addo, M, Mothe, B, Rathod, A, Reyor, L, Harlow, J, Yu, X, Perkins, B, Robinson, L, Sidney, J, Alter, G, Lichterfeld, M, Sette, A, Rosenberg, E, Goulder, P, Brander, C, Walker, B

HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load. by Frahm, N, Adams, S, Kiepiela, P, Linde, C, Hewitt, H, Lichterfeld, M, Sango, K, Brown, N, Pae, E, Wurcel, A, Altfeld, M, Feeney, M, Allen, T, Roach, T, John, S, Daar, E, Rosenberg, E, Korber, B, Marincola, F, Walker, B, Goulder, P, Brander, C

Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes. by Frahm, N, Kiepiela, P, Adams, S, Linde, C, Hewitt, H, Sango, K, Feeney, M, Addo, M, Lichterfeld, M, Lahaie, M, Pae, E, Wurcel, A, Roach, T, John, S, Altfeld, M, Marincola, F, Moore, C, Mallal, S, Carrington, M, Heckerman, D, Allen, T, Mullins, J, Korber, B, Goulder, P, Walker, B

HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load. by Rousseau, C, Daniels, MG, Carlson, J, Kadie, C, Crawford, H, Prendergast, A, Matthews, P, Payne, R, Rolland, M, Raugi, D, Maust, B, Learn, G, Nickle, D, Coovadia, H, Ndung'u, T, Frahm, N, Brander, C, Walker, B, Goulder, P, Bhattacharya, T, Heckerman, D, Korber, B, Mullins, J

Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians. by Yu, X, Addo, M, Perkins, B, Wej, F, Rathod, A, Geer, S, Parta, M, Cohen, D, Stone, DR, Russell, C, Tanzi, G, Mei, S, Wurcel, A, Frahm, N, Lichterfeld, M, Heath, L, Mullins, J, Marincola, F, Goulder, P, Brander, C, Allen, T, Cao, Y, Walker, B, Altfeld, M

Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference be... by Yu, X, Lichterfeld, M, Chetty, S, Williams, K, Mui, S, Miura, T, Frahm, N, Feeney, M, Tang, Y, Pereyra, F, Labute, M, Pfafferott, K, Leslie, A, Crawford, H, Allgaier, R, Hildebrand, W, Kaslow, R, Brander, C, Allen, T, Rosenberg, E, Kiepiela, P, Vajpayee, M, Goepfert, P, Altfeld, M, Goulder, P