Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment Autor Franck Verrecchia, Françoise Rédini

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The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem Autor Isabelle Corre, Franck Verrecchia, Vincent Crenn, Francoise Redini, Valérie Trichet

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Antagonistic Functions of Connexin 43 during the Development of Primary or Secondary Bone Tumors Autor Julie Talbot, Maryne Dupuy, Sarah Morice, Françoise Rédini, Franck Verrecchia

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SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression Autor Frédéric Lézot, Isabelle Corre, Sarah Morice, Françoise Rédini, Franck Verrecchia

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LIM Kinases in Osteosarcoma Development Autor Régis Brion, Laura Regnier, Mathilde Mullard, Jérome Amiaud, Françoise Rédini, Franck Verrecchia

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Tumor Suppressive Role of miR-342-5p and miR-491-5p in Human Osteosarcoma Cells Autor Clément Veys, Manon Jammes, Françoise Rédini, Laurent Poulain, Christophe Denoyelle, Florence Legendre, Philippe Galera

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Exposure of primary bone tumor-associated stromal cells to multi-pesticides at low doses and paracrine effects on osteoclast differentiation Autor Valérie Trichet, Louis-Romée Le Nail, Régis Brion, Françoise Rédini, François Vallette, Olivier Hérault, Christophe Olivier

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Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models. Autor Bérengère Gobin, Gatien Moriceau, Benjamin Ory, Céline Charrier, Régis Brion, Frederic Blanchard, Françoise Redini, Dominique Heymann

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Pyridazinone scaffold-based molecules decrease osteosarcoma cells growth Autor Aurélie Moniot, Julien Braux, Christine Guillaume, Ingrid Allart-Simon, Sandra Audonnet, Sarah Renault, Françoise Rédini, Janos Sapi, Sophie C. Gangloff, Stéphane Gérard, Frédéric Velard

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Safety concern between autologous fat graft, mesenchymal stem cell and osteosarcoma recurrence. Autor Pierre Perrot, Julie Rousseau, Anne-Laure Bouffaut, Françoise Rédini, Elisabeth Cassagnau, Frédéric Deschaseaux, Marie-Françoise Heymann, Dominique Heymann, Franck Duteille, Valérie Trichet, François Gouin

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Ewing sarcoma from molecular biology to the clinic Autor Maryne Dupuy, François Lamoureux, Mathilde Mullard, Anaïs Postec, Laura Regnier, Marc Baud’huin, Steven Georges, Bénédicte Brounais-Le Royer, Benjamin Ory, Françoise Rédini, Franck Verrecchia

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Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis Autor Sarah Morice, Geoffroy Danieau, Robel Tesfaye, Mathilde Mullard, Régis Brion, Régis Brion, Maryne Dupuy, Benjamin Ory, Bénédicte Brounais-Le Royer, Isabelle Corre, Françoise Redini, Franck Verrecchia

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ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells Autor Geoffroy Danieau, Sarah Morice, Sarah Renault, Régis Brion, Kevin Biteau, Jérôme Amiaud, Marie Cadé, Dominique Heymann, Frédéric Lézot, Franck Verrecchia, Françoise Rédini, Bénédicte Brounais-Le Royer

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Sponge Morphology of Osteosarcoma Finds Origin in Synergy Between Bone Synthesis and Tumor Growth Autor Arnaud Bardouil, Thomas Bizien, Jérome Amiaud, Alain Fautrel, Séverine Battaglia, Iman Almarouk, Tanguy Rouxel, Pascal Panizza, Javier Perez, Arndt Last, Chakib Djediat, Elora Bessot, Nadine Nassif, Françoise Rédini, Franck Artzner

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Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development... Autor Mélanie Lavaud, Mathilde Mullard, Robel Tesfaye, Jérôme Amiaud, Mélanie Legrand, Geoffroy Danieau, Régis Brion, Sarah Morice, Laura Regnier, Maryne Dupuy, Bénédicte Brounais-Le Royer, François Lamoureux, Benjamin Ory, Françoise Rédini, Franck Verrecchia

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Transcriptional regulation of KCNA2 coding Kv1.2 by EWS::FLI1: involvement in controlling the YAP/Hippo signalling pathway and cell proliferation Autor Maryne Dupuy, Anaïs Postec, Mathilde Mullard, Aurélie Chantôme, Philippe Hulin, Régis Brion, Maxime Gueguinou, Laura Regnier, Marie Potier-Cartereau, Bénédicte Brounais-Le Royer, Marc Baud’huin, Steven Georges, François Lamoureux, Benjamin Ory, Françoise Rédini, Christophe Vandier, Franck Verrecchia

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MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells Autor Clément Veys, Flavie Boulouard, Flavie Boulouard, Abderrahim Benmoussa, Abderrahim Benmoussa, Manon Jammes, Emilie Brotin, Emilie Brotin, Emilie Brotin, Françoise Rédini, Laurent Poulain, Laurent Poulain, Nicolas Gruchy, Nicolas Gruchy, Christophe Denoyelle, Christophe Denoyelle, Christophe Denoyelle, Florence Legendre, Philippe Galera

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Integrated molecular characterization of chondrosarcoma reveals critical determinants of disease progression Autor Rémy Nicolle, Mira Ayadi, Anne Gomez-Brouchet, Lucile Armenoult, Guillaume Banneau, Nabila Elarouci, Matthias Tallegas, Anne-Valérie Decouvelaere, Sébastien Aubert, Françoise Rédini, Béatrice Marie, Corinne Labit-Bouvier, Nicolas Reina, Marie Karanian, Louis-Romée le Nail, Philippe Anract, François Gouin, Frédérique Larousserie, Aurélien de Reyniès, Gonzague de Pinieux

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A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors Autor Maria Eugénia Marques Da Costa, Sakina Zaidi, Jean-Yves Scoazec, Robin Droit, Wan Ching Lim, Antonin Marchais, Jerome Salmon, Sarah Cherkaoui, Raphael J. Morscher, Anouchka Laurent, Sébastien Malinge, Thomas Mercher, Séverine Tabone-Eglinger, Isabelle Goddard, Francoise Pflumio, Julien Calvo, Francoise Redini, Natacha Entz-Werlé, Aroa Soriano, Alberto Villanueva, Stefano Cairo, Pascal Chastagner, Massimo Moro, Cormac Owens, Michela Casanova, Raquel Hladun-Alvaro, Pablo Berlanga, Estelle Daudigeos-Dubus, Philippe Dessen, Laurence Zitvogel, Ludovic Lacroix, Gaelle Pierron, Olivier Delattre, Gudrun Schleiermacher, Didier Surdez, Birgit Geoerger

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