Low Cell Bioenergetic Metabolism Characterizes Chronic Lymphocytic Leukemia Patients with Unfavorable Genetic Factors and with a Better Response to BTK Inhibition by Simone Mirabilii, Monica Piedimonte, Esmeralda Conte, Daniele Mirabilii, Francesca Maria Rossi, Riccardo Bomben, Antonella Zucchetto, Valter Gattei, Agostino Tafuri, Maria Rosaria Ricciardi

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THE ROLE OF CD49D IN CHRONIC LYMPHOCYTIC LEUKAEMIA: MICROENVIRONMENTAL INTERACTIONS AND CLINICAL RELEVANCE by Michele Dal Bo, Erika Tissino, Dania Benedetti, Chiara Caldana, Riccardo Bomben, Giovanni Del Poeta, Gianluca Gaidano, Francesca Maria Rossi, Antonella Zucchetto, Valter Gattei

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Improved GMP compliant approach to manipulate lipoaspirates, to cryopreserve stromal vascular fraction, and to expand adipose stem cells in xeno-free media by Francesco Agostini, Francesca Maria Rossi, Donatella Aldinucci, Monica Battiston, Elisabetta Lombardi, Stefania Zanolin, Samuele Massarut, Pier Camillo Parodi, Alessandro Da Ponte, Giovanni Tessitori, Barbara Pivetta, Cristina Durante, Mario Mazzucato

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A B-cell receptor-related gene signature predicts response to ibrutinib treatment in mantle cell lymphoma cell lines by Tiziana D’Agaro, Antonella Zucchetto, Filippo Vit, Tamara Bittolo, Erika Tissino, Francesca Maria Rossi, Massimo Degan, Francesco Zaja, Pietro Bulian, Michele Dal Bo, Simone Ferrero, Marco Ladetto, Alberto Zamò, Valter Gattei, Riccardo Bomben

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CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia by Davide Rossi, Antonella Zucchetto, Francesca Maria Rossi, Daniela Capello, Michaela Cerri, Clara Deambrogi, Stefania Cresta, Silvia Rasi, Lorenzo De Paoli, Chiara Lobetti Bodoni, Pietro Bulian, Giovanni Del Poeta, Marco Ladetto, Valter Gattei, Gianluca Gaidano

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Impaired nodal shrinkage and apoptosis define the independent adverse outcome of NOTCH1 mutated patients under ibrutinib therapy in chronic lymphocytic leukaemia by Giovanni Del Poeta, Annalisa Biagi, Luca Laurenti, Annalisa Chiarenza, Federico Pozzo, Idanna Innocenti, Massimiliano Postorino, Francesca Maria Rossi, Maria Ilaria Del Principe, Riccardo Bomben, Paolo de Fabritiis, Antonio Bruno, Maria Cantonetti, Francesco Di Raimondo, Antonella Zucchetto, Valter Gattei

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Clinical significance of bax/bcl-2 ratio in chronic lymphocytic leukemia by Maria Ilaria Del Principe, Michele Dal Bo, Tamara Bittolo, Francesco Buccisano, Francesca Maria Rossi, Antonella Zucchetto, Davide Rossi, Riccardo Bomben, Luca Maurillo, Mariagiovanna Cefalo, Giovanna De Santis, Adriano Venditti, Gianluca Gaidano, Sergio Amadori, Paolo de Fabritiis, Valter Gattei, Giovanni Del Poeta

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<i>SF3B1</i>-mutated chronic lymphocytic leukemia shows evidence of NOTCH1 pathway activation including CD20 downregulation by Federico Pozzo, Tamara Bittolo, Erika Tissino, Filippo Vit, Elena Vendramini, Luca Laurenti, Giovanni D’Arena, Jacopo Olivieri, Gabriele Pozzato, Francesco Zaja, Annalisa Chiarenza, Francesco Di Raimondo, Antonella Zucchetto, Riccardo Bomben, Francesca Maria Rossi, Giovanni Del Poeta, Michele Dal Bo, Valter Gattei

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CD69 is independently prognostic in chronic lymphocytic leukemia: a comprehensive clinical and biological profiling study by Giovanni Del Poeta, Maria Ilaria Del Principe, Antonella Zucchetto, Fabrizio Luciano, Francesco Buccisano, Francesca Maria Rossi, Antonio Bruno, Annalisa Biagi, Pietro Bulian, Luca Maurillo, Benedetta Neri, Riccardo Bomben, Cristina Simotti, Angela Maria Coletta, Michele Dal Bo, Paolo de Fabritiis, Adriano Venditti, Valter Gattei, Sergio Amadori

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Mutations in the 3′ untranslated region of NOTCH1 are associated with low CD20 expression levels chronic lymphocytic leukemia by Tamara Bittolo, Federico Pozzo, Riccardo Bomben, Tiziana D’Agaro, Vanessa Bravin, Pietro Bulian, Francesca Maria Rossi, Antonella Zucchetto, Massimo Degan, Paolo Macor, Giovanni D’Arena, Annalisa Chiarenza, Francesco Zaja, Gabriele Pozzato, Francesco Di Raimondo, Davide Rossi, Gianluca Gaidano, Giovanni Del Poeta, Valter Gattei, Michele Dal Bo

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Mutational status of IGHV is the most reliable prognostic marker in trisomy 12 chronic lymphocytic leukemia by Pietro Bulian, Riccardo Bomben, Michele Dal Bo, Antonella Zucchetto, Francesca Maria Rossi, Massimo Degan, Federico Pozzo, Tamara Bittolo, Vanessa Bravin, Tiziana D’Agaro, Michaela Cerri, Annalisa Chiarenza, Kari G. Chaffee, Adalgisa Condoluci, Giovanni D’Arena, Michele Spina, Francesco Zaja, Gabriele Pozzato, Francesco Di Raimondo, Davide Rossi, Giovanni Del Poeta, Gianluca Gaidano, Tait D. Shanafelt, Valter Gattei

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S143: NATURAL CLONAL EVOLUTION OF CHRONIC LYMPHOCYTIC LEUKEMIA WITH BIMODAL CD49D EXPRESSION REVEALS CD49D PLASTICITY by Erika Tissino, Nicola Calonaci, Federico Pozzo, Filippo Vit, Annalisa Gaglio, Lodovico Terzi DI Bergamo, Tamara Bittolo, Francesca Maria Rossi, Robel Papotti, Ilaria Catarossi, Eva Zaina, Paola Nanni, Riccardo Bergamin, Leonardo Egidi, Giovanni Santacatterina, Salvatore Milite, Maria Ilaria Del Principe, Roberta Laureana, Jacopo Olivieri, Francesco Zaja, Annalisa Chiarenza, Davide Rossi, Riccardo Bomben, Valter Gattei, Antonella Zucchetto, Giulio Caravagna

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A laboratory-based scoring system predicts early treatment in Rai 0 chronic lymphocytic leukemia by Jared A. Cohen, Francesca Maria Rossi, Antonella Zucchetto, Riccardo Bomben, Lodovico Terzi-di-Bergamo, Kari G. Rabe, Massimo Degan, Agostino Steffan, Jerry Polesel, Enrico Santinelli, Idanna Innocenti, Giovanna Cutrona, Giovanni D’Arena, Gabriele Pozzato, Francesco Zaja, Annalisa Chiarenza, Davide Rossi, Francesco Di Raimondo, Luca Laurenti, Massimo Gentile, Fortunato Morabito, Antonino Neri, Manlio Ferrarini, Christopher D. Fegan, Christopher J. Pepper, Giovanni Del Poeta, Sameer A. Parikh, Neil E. Kay, Valter Gattei

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Biological and clinical implications of BIRC3 mutations in chronic lymphocytic leukemia by Fary Diop, Riccardo Moia, Chiara Favini, Elisa Spaccarotella, Lorenzo De Paoli, Alessio Bruscaggin, Valeria Spina, Lodovico Terzi-di-Bergamo, Francesca Arruga, Chiara Tarantelli, Clara Deambrogi, Silvia Rasi, Ramesh Adhinaveni, Andrea Patriarca, Simone Favini, Sruthi Sagiraju, Clive Jabangwe, Ahad A. Kodipad, Denise Peroni, Francesca R. Mauro, Ilaria Del Giudice, Francesco Forconi, Agostino Cortelezzi, Francesco Zaja, Riccardo Bomben, Francesca Maria Rossi, Carlo Visco, Annalisa Chiarenza, Gian Matteo Rigolin, Roberto Marasca, Marta Coscia, Omar Perbellini, Alessandra Tedeschi, Luca Laurenti, Marina Motta, David Donaldson, Phil Weir, Ken Mills, Patrick Thornton, Sarah Lawless, Francesco Bertoni, Giovanni Del Poeta, Antonio Cuneo, Antonia Follenzi, Valter Gattei, Renzo Luciano Boldorini, Mark Catherwood, Silvia Deaglio, Robin Foà, Gianluca Gaidano°, Davide Rossi°

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