Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models by Kathleen Sprouffske, Grainne Kerr, Cheng Li, Anirudh Prahallad, Ramona Rebmann, Verena Waehle, Ulrike Naumann, Hans Bitter, Michael R Jensen, Francesco Hofmann, Saskia M Brachmann, Stéphane Ferretti, Audrey Kauffmann

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K-RAS mutant pancreatic tumors show higher sensitivity to MEK than to PI3K inhibition in vivo. by Irmgard Hofmann, Andreas Weiss, Gaelle Elain, Maria Schwaederle, Dario Sterker, Vincent Romanet, Tobias Schmelzle, Albert Lai, Saskia M Brachmann, Mohamed Bentires-Alj, Thomas M Roberts, William R Sellers, Francesco Hofmann, Sauveur-Michel Maira

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Fibroblast growth factor receptors as novel therapeutic targets in SNF5-deleted malignant rhabdoid tumors. by Simon Wöhrle, Andreas Weiss, Moriko Ito, Audrey Kauffmann, Masato Murakami, Zainab Jagani, Anne Thuery, Beatrice Bauer-Probst, Flavia Reimann, Christelle Stamm, Astrid Pornon, Vincent Romanet, Vito Guagnano, Thomas Brümmendorf, William R Sellers, Francesco Hofmann, Charles W M Roberts, Diana Graus Porta

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A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression. by Emilie A Chapeau, Emeline Mandon, Jason Gill, Vincent Romanet, Nicolas Ebel, Violetta Powajbo, Rita Andraos-Rey, Zhiyan Qian, Miltos Kininis, Sabine Zumstein-Mecker, Moriko Ito, Nancy E Hynes, Ralph Tiedt, Francesco Hofmann, Leonid Eshkind, Ernesto Bockamp, Bernd Kinzel, Matthias Mueller, Masato Murakami, Fabienne Baffert, Thomas Radimerski

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Correction: A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097 by Sébastien Jeay, Swann Gaulis, Stéphane Ferretti, Hans Bitter, Moriko Ito, Thérèse Valat, Masato Murakami, Stephan Ruetz, Daniel A Guthy, Caroline Rynn, Michael R Jensen, Marion Wiesmann, Joerg Kallen, Pascal Furet, François Gessier, Philipp Holzer, Keiichi Masuya, Jens Würthner, Ensar Halilovic, Francesco Hofmann, William R Sellers, Diana Graus Porta

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A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097 by Sébastien Jeay, Swann Gaulis, Stéphane Ferretti, Hans Bitter, Moriko Ito, Thérèse Valat, Masato Murakami, Stephan Ruetz, Daniel A Guthy, Caroline Rynn, Michael R Jensen, Marion Wiesmann, Joerg Kallen, Pascal Furet, François Gessier, Philipp Holzer, Keiichi Masuya, Jens Würthner, Ensar Halilovic, Francesco Hofmann, William R Sellers, Diana Graus Porta

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