The Tumour Suppressor Fhit Protein Activates C-Raf Ubiquitination and Degradation in Human Melanoma Cells by Interacting with Hsp90 by Francesco Paduano, Eugenio Gaudio, Francesco Trapasso

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Case Report: Identification of a Novel Pathogenic Germline TP53 Variant in a Family With Li–Fraumeni Syndrome by Francesco Paduano, Francesco Paduano, Francesco Paduano, Fernanda Fabiani, Emma Colao, Francesco Trapasso, Francesco Trapasso, Nicola Perrotti, Nicola Perrotti, Vito Barbieri, Francesco Baudi, Rodolfo Iuliano, Rodolfo Iuliano

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T-Cell Leukemia/Lymphoma 1 (TCL1): An Oncogene Regulating Multiple Signaling Pathways by Francesco Paduano, Francesco Paduano, Eugenio Gaudio, Afua A. Mensah, Sandra Pinton, Francesco Bertoni, Francesco Trapasso

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7q35 Microdeletion and 15q13.3 and Xp22.33 Microduplications in a Patient with Severe Myoclonic Epilepsy, Microcephaly, Dysmorphisms, Severe Psychomotor Delay and Intellectual Disa... by Francesco Paduano, Emma Colao, Sara Loddo, Valeria Orlando, Francesco Trapasso, Antonio Novelli, Nicola Perrotti, Rodolfo Iuliano

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RANBP1 (RAN Binding Protein 1): The Missing Genetic Piece in Cancer Pathophysiology and Other Complex Diseases by Salvatore Audia, Carolina Brescia, Vincenzo Dattilo, Lucia D’Antona, Pierluigi Calvano, Rodolfo Iuliano, Francesco Trapasso, Nicola Perrotti, Rosario Amato

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Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma by Francesca Alessandra Ambrosio, Giosuè Costa, Maria Eugenia Gallo Cantafio, Roberta Torcasio, Francesco Trapasso, Stefano Alcaro, Giuseppe Viglietto, Nicola Amodio

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RANBP1, a member of the nuclear-cytoplasmic trafficking-regulator complex, is the terminal-striking point of the SGK1-dependent Th17+ pathological differentiation by Carolina Brescia, Carolina Brescia, Vincenzo Dattilo, Lucia D’Antona, Lucia D’Antona, Emanuela Chiarella, Rossana Tallerico, Salvatore Audia, Salvatore Audia, Valentina Rocca, Valentina Rocca, Rodolfo Iuliano, Rodolfo Iuliano, Francesco Trapasso, Francesco Trapasso, Nicola Perrotti, Nicola Perrotti, Rosario Amato, Rosario Amato, Rosario Amato

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Natural Products Extracted from Fungal Species as New Potential Anti-Cancer Drugs: A Structure-Based Drug Repurposing Approach Targeting HDAC7 by Annalisa Maruca, Roberta Rocca, Raffaella Catalano, Francesco Mesiti, Giosuè Costa, Delia Lanzillotta, Alessandro Salatino, Francesco Ortuso, Francesco Trapasso, Stefano Alcaro, Anna Artese

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New Insights for Polyphenolic Compounds as Naturally Inspired Proteasome Inhibitors by Emanuela Marchese, Maria Eugenia Gallo Cantafio, Francesca Alessandra Ambrosio, Roberta Torcasio, Ilenia Valentino, Francesco Trapasso, Giuseppe Viglietto, Stefano Alcaro, Giosuè Costa, Nicola Amodio

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A familial t(4;8) translocation segregates with epilepsy and migraine with aura by Milena Crippa, Paola Malatesta, Maria Teresa Bonati, Francesco Trapasso, Francesco Fortunato, Grazia Annesi, Lidia Larizza, Angelo Labate, Palma Finelli, Nicola Perrotti, Antonio Gambardella

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Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors by Annalisa Maruca, Delia Lanzillotta, Roberta Rocca, Antonio Lupia, Giosuè Costa, Raffaella Catalano, Federica Moraca, Eugenio Gaudio, Francesco Ortuso, Anna Artese, Francesco Trapasso, Stefano Alcaro

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Germline Testing in a Cohort of Patients at High Risk of Hereditary Cancer Predisposition Syndromes: First Two-Year Results from South Italy by Francesco Paduano, Emma Colao, Fernanda Fabiani, Valentina Rocca, Francesca Dinatolo, Adele Dattola, Lucia D’Antona, Rosario Amato, Francesco Trapasso, Francesco Baudi, Nicola Perrotti, Rodolfo Iuliano

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Corrigendum: Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides by Maria Carmina Scala, Simone Di Micco, Delia Lanzillotta, Simona Musella, Veronica Di Sarno, Barbara Parrino, Stella Maria Cascioferro, Giuseppe Bifulco, Francesco Trapasso, Pietro Campiglia, Marina Sala

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Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies by Gianmarco Gualtieri, Annalisa Maruca, Roberta Rocca, Fabrizio Carta, Emanuela Berrino, Alessandro Salatino, Carolina Brescia, Roberta Torcasio, Manuel Crispo, Francesco Trapasso, Stefano Alcaro, Claudiu T. Supuran, Giosuè Costa

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Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides by Maria Carmina Scala, Simone Di Micco, Delia Lanzillotta, Simona Musella, Veronica Di Sarno, Barbara Parrino, Stella Maria Cascioferro, Giuseppe Bifulco, Francesco Trapasso, Pietro Campiglia, Marina Sala

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In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition by Giosuè Costa, Annalisa Maruca, Roberta Rocca, Francesca Alessandra Ambrosio, Emanuela Berrino, Fabrizio Carta, Francesco Mesiti, Alessandro Salatino, Delia Lanzillotta, Francesco Trapasso, Anna Artese, Stefano Alcaro, Claudiu T. Supuran

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A Familial Form of Epidermolysis Bullosa Simplex Associated with a Pathogenic Variant in <i>KRT5</i> by Francesco Paduano, Emma Colao, Teresa Grillone, Marco Flavio Michele Vismara, Rosario Amato, Steven Nisticò, Chiara Mignogna, Stefano Dastoli, Fernanda Fabiani, Rossella Zucco, Francesco Trapasso, Nicola Perrotti, Rodolfo Iuliano

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Th17-Gene Expression Profile in Patients with Chronic Venous Disease and Venous Ulcers: Genetic Modulations and Preliminary Clinical Evidence by Rosario Amato, Vincenzo Dattilo, Carolina Brescia, Lucia D’Antona, Rodolfo Iuliano, Francesco Trapasso, Nicola Perrotti, Davide Costa, Nicola Ielapi, Francesco Aiello, Michele Provenzano, Umberto Marcello Bracale, Michele Andreucci, Raffaele Serra

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Fhit delocalizes annexin a4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel. by Eugenio Gaudio, Francesco Paduano, Riccardo Spizzo, Apollinaire Ngankeu, Nicola Zanesi, Marco Gaspari, Francesco Ortuso, Francesca Lovat, Jonathan Rock, Grace A Hill, Mohamed Kaou, Giovanni Cuda, Rami I Aqeilan, Stefano Alcaro, Carlo M Croce, Francesco Trapasso

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SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation by Lucia D''Antona, Rosario Amato, Cristina Talarico, Francesco Ortuso, Miranda Menniti, Vincenzo Dattilo, Rodolfo Iuliano, Francesco Gigliotti, Anna Artese, Giosuè Costa, Silvia Schenone, Francesca Musumeci, Claudia Abbruzzese, Lorenzo Botta, Francesco Trapasso, Stefano Alcaro, Marco G. Paggi, Nicola Perrotti

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