Showing 1 - 20 results of 20 for search 'Francisco Javier Gamo', query time: 0.07s
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Phenotypic screens, chemical genomics, and antimalarial lead discovery. by Jose F Garcia-Bustos, Francisco-Javier Gamo
Published 2011-08-01
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Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarial... by Oleksiy Tsebriy, Andrii Khomiak, Celia Miguel-Blanco, Penny C Sparkes, Maurizio Gioli, Marco Santelli, Edgar Whitley, Francisco-Javier Gamo, Michael J Delves
Published 2023-10-01
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Fueling Open Innovation for Malaria Transmission-Blocking Drugs: Hundreds of Molecules Targeting Early Parasite Mosquito Stages by Michael Delves, Michael Delves, M. Jose Lafuente-Monasterio, Leanna Upton, Andrea Ruecker, Andrea Ruecker, Andrea Ruecker, Didier Leroy, Francisco-Javier Gamo, Robert Sinden
Published 2019-09-01
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Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance by Rebecca EK Mandt, Madeline R Luth, Mark A Tye, Ralph Mazitschek, Sabine Ottilie, Elizabeth A Winzeler, Maria Jose Lafuente-Monasterio, Francisco Javier Gamo, Dyann F Wirth, Amanda K Lukens
Published 2023-09-01
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The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of <i>Plasmodium falciparum</i> Viability after Antimalarial Treatment In Vitro by Annabelle Walz, Maëlle Duffey, Ghaith Aljayyoussi, Sibylle Sax, Didier Leroy, Dominique Besson, Jeremy N. Burrows, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Marie-Anne Westwood, Christoph Siethoff, Francisco-Javier Gamo, Pascal Mäser, Sergio Wittlin
Published 2023-01-01
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Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors by Hao-Chi Hsu, Daqiang Li, Wenhu Zhan, Jianxiang Ye, Yi Jing Liu, Annie Leung, Junling Qin, Benigno Crespo, Francisco-Javier Gamo, Hao Zhang, Liwang Cui, Alison Roth, Laura A. Kirkman, Huilin Li, Gang Lin
Published 2023-12-01
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Inhibitors of ApiAP2 protein DNA binding exhibit multistage activity against Plasmodium parasites. by Timothy James Russell, Erandi K De Silva, Valerie M Crowley, Kathryn Shaw-Saliba, Namita Dube, Gabrielle Josling, Charisse Flerida A Pasaje, Irene Kouskoumvekaki, Gianni Panagiotou, Jacquin C Niles, Marcelo Jacobs-Lorena, C Denise Okafor, Francisco-Javier Gamo, Manuel Llinás
Published 2022-10-01
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Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening by Mario Carucci, Julien Duez, Joel Tarning, Irene García-Barbazán, Aurélie Fricot-Monsinjon, Abdoulaye Sissoko, Lucie Dumas, Pablo Gamallo, Babette Beher, Pascal Amireault, Michael Dussiot, Ming Dao, Mitchell V. Hull, Case W. McNamara, Camille Roussel, Papa Alioune Ndour, Laura Maria Sanz, Francisco Javier Gamo, Pierre Buffet
Published 2023-04-01
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A new in vivo screening paradigm to accelerate antimalarial drug discovery. by María Belén Jiménez-Díaz, Sara Viera, Javier Ibáñez, Teresa Mulet, Noemí Magán-Marchal, Helen Garuti, Vanessa Gómez, Lorena Cortés-Gil, Antonio Martínez, Santiago Ferrer, María Teresa Fraile, Félix Calderón, Esther Fernández, Leonard D Shultz, Didier Leroy, David M Wilson, José Francisco García-Bustos, Francisco Javier Gamo, Iñigo Angulo-Barturen
Published 2013-01-01
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The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957 by Celia Miguel-Blanco, James M. Murithi, Ernest Diez Benavente, Fiona Angrisano, Katarzyna A. Sala, Donelly A. van Schalkwyk, Manu Vanaerschot, Frank Schwach, Matthew J. Fuchter, Oliver Billker, Colin J. Sutherland, Susana G. Campino, Taane G. Clark, Andrew M. Blagborough, David A. Fidock, Esperanza Herreros, Francisco Javier Gamo, Jake Baum, Michael J. Delves
Published 2021-01-01
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A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue by Ebere Sonoiki, Caroline L. Ng, Marcus C. S. Lee, Denghui Guo, Yong-Kang Zhang, Yasheen Zhou, M. R. K. Alley, Vida Ahyong, Laura M. Sanz, Maria Jose Lafuente-Monasterio, Chen Dong, Patrick G. Schupp, Jiri Gut, Jenny Legac, Roland A. Cooper, Francisco-Javier Gamo, Joseph DeRisi, Yvonne R. Freund, David A. Fidock, Philip J. Rosenthal
Published 2017-03-01
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Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum by Krittikorn Kümpornsin, Theerarat Kochakarn, Tomas Yeo, John Okombo, Madeline R. Luth, Johanna Hoshizaki, Mukul Rawat, Richard D. Pearson, Kyra A. Schindler, Sachel Mok, Heekuk Park, Anne-Catrin Uhlemann, Gouranga P. Jana, Bikash C. Maity, Benoît Laleu, Elodie Chenu, James Duffy, Sonia Moliner Cubel, Virginia Franco, Maria G. Gomez-Lorenzo, Francisco Javier Gamo, Elizabeth A. Winzeler, David A. Fidock, Thanat Chookajorn, Marcus C. S. Lee
Published 2023-05-01
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A broad analysis of resistance development in the malaria parasite by Victoria C. Corey, Amanda K. Lukens, Eva S. Istvan, Marcus C. S. Lee, Virginia Franco, Pamela Magistrado, Olivia Coburn-Flynn, Tomoyo Sakata-Kato, Olivia Fuchs, Nina F. Gnädig, Greg Goldgof, Maria Linares, Maria G. Gomez-Lorenzo, Cristina De Cózar, Maria Jose Lafuente-Monasterio, Sara Prats, Stephan Meister, Olga Tanaseichuk, Melanie Wree, Yingyao Zhou, Paul A. Willis, Francisco-Javier Gamo, Daniel E. Goldberg, David A. Fidock, Dyann F. Wirth, Elizabeth A. Winzeler
Published 2016-06-01
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Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation by Selina Bopp, Charisse Flerida A. Pasaje, Robert L. Summers, Pamela Magistrado-Coxen, Kyra A. Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok, Sumanta Dey, Sebastian Smick, Armiyaw S. Nasamu, Allison R. Demas, Rachel Milne, Natalie Wiedemar, Victoria Corey, Maria De Gracia Gomez-Lorenzo, Virginia Franco, Angela M. Early, Amanda K. Lukens, Danny Milner, Jeremy Furtado, Francisco-Javier Gamo, Elizabeth A. Winzeler, Sarah K. Volkman, Maëlle Duffey, Benoît Laleu, David A. Fidock, Susan Wyllie, Jacquin C. Niles, Dyann F. Wirth
Published 2023-03-01
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A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission by David A. Baker, Lindsay B. Stewart, Jonathan M. Large, Paul W. Bowyer, Keith H. Ansell, María B. Jiménez-Díaz, Majida El Bakkouri, Kristian Birchall, Koen J. Dechering, Nathalie S. Bouloc, Peter J. Coombs, David Whalley, Denise J. Harding, Ela Smiljanic-Hurley, Mary C. Wheldon, Eloise M. Walker, Johannes T. Dessens, María José Lafuente, Laura M. Sanz, Francisco-Javier Gamo, Santiago B. Ferrer, Raymond Hui, Teun Bousema, Iñigo Angulo-Barturén, Andy T. Merritt, Simon L. Croft, Winston E. Gutteridge, Catherine A. Kettleborough, Simon A. Osborne
Published 2017-09-01
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The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations by Jorge E. B. da Rocha, Jorge E. B. da Rocha, Houcemeddine Othman, Gerrit Botha, Laura Cottino, Laura Cottino, David Twesigomwe, David Twesigomwe, Samah Ahmed, Britt I. Drögemöller, Faisal M. Fadlelmola, Philip Machanick, Mamana Mbiyavanga, Sumir Panji, Galen E. B. Wright, Galen E. B. Wright, Clement Adebamowo, Clement Adebamowo, Mogomotsi Matshaba, Mogomotsi Matshaba, Michéle Ramsay, Michéle Ramsay, Gustave Simo, Martin C. Simuunza, Caroline T. Tiemessen, Sandra Baldwin, Mathias Chiano, Charles Cox, Annette S. Gross, Pamela Thomas, Francisco-Javier Gamo, Scott Hazelhurst, Scott Hazelhurst
Published 2021-04-01
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Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling. by Amélie Le Bihan, Ruben de Kanter, Iñigo Angulo-Barturen, Christoph Binkert, Christoph Boss, Reto Brun, Ralf Brunner, Stephan Buchmann, Jeremy Burrows, Koen J Dechering, Michael Delves, Sonja Ewerling, Santiago Ferrer, Christoph Fischli, Francisco Javier Gamo-Benito, Nina F Gnädig, Bibia Heidmann, María Belén Jiménez-Díaz, Didier Leroy, Maria Santos Martínez, Solange Meyer, Joerg J Moehrle, Caroline L Ng, Rintis Noviyanti, Andrea Ruecker, Laura María Sanz, Robert W Sauerwein, Christian Scheurer, Sarah Schleiferboeck, Robert Sinden, Christopher Snyder, Judith Straimer, Grennady Wirjanata, Jutta Marfurt, Ric N Price, Thomas Weller, Walter Fischli, David A Fidock, Martine Clozel, Sergio Wittlin
Published 2016-10-01
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Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles by Alice E. Williamson, Paul M. Ylioja, Murray N. Robertson, Yevgeniya Antonova-Koch, Vicky Avery, Jonathan B. Baell, Harikrishna Batchu, Sanjay Batra, Jeremy N. Burrows, Soumya Bhattacharyya, Felix Calderon, Susan A. Charman, Julie Clark, Benigno Crespo, Matin Dean, Stefan L. Debbert, Michael Delves, Adelaide S. M. Dennis, Frederik Deroose, Sandra Duffy, Sabine Fletcher, Guri Giaever, Irene Hallyburton, Francisco-Javier Gamo, Marinella Gebbia, R. Kiplin Guy, Zoe Hungerford, Kiaran Kirk, Maria J. Lafuente-Monasterio, Anna Lee, Stephan Meister, Corey Nislow, John P. Overington, George Papadatos, Luc Patiny, James Pham, Stuart A. Ralph, Andrea Ruecker, Eileen Ryan, Christopher Southan, Kumkum Srivastava, Chris Swain, Matthew J. Tarnowski, Patrick Thomson, Peter Turner, Iain M. Wallace, Timothy N. C. Wells, Karen White, Laura White, Paul Willis, Elizabeth A. Winzeler, Sergio Wittlin, Matthew H. Todd
Published 2016-09-01
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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 by Laura E. de Vries, Patrick A. M. Jansen, Catalina Barcelo, Justin Munro, Julie M. J. Verhoef, Charisse Flerida A. Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M. Bolscher, Claudia Demarta-Gatsi, Rob W. M. Henderson, Tonnie Huijs, Karin M. J. Koolen, Patrick K. Tumwebaze, Tomas Yeo, Anna C. C. Aguiar, Iñigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael V. C. Guido, María Belén Jiménez-Diaz, Dhelio B. Pereira, Rosemary Rochford, Camille Roesch, Laura M. Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W. Sauerwein, Joost Schalkwijk, Pedro H. H. Hermkens, Roger V. Bonnert, Brice Campo, David A. Fidock, Manuel Llinás, Jacquin C. Niles, Taco W. A. Kooij, Koen J. Dechering
Published 2022-04-01
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