Editorial: Innovative Strategies From Synthetic Biology and Bacterial Pathways to Master Biochemical Environmental Challenges by Frank Eisenhaber, Frank Eisenhaber, Frank Eisenhaber, Juilee Thakar, Alicia Ponte-Sucre, Thomas Dandekar

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More than 1,001 problems with protein domain databases: transmembrane regions, signal peptides and the issue of sequence homology. by Wing-Cheong Wong, Sebastian Maurer-Stroh, Frank Eisenhaber

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In Memory of Vladimir B. Bajic (1952–2019) by Zhang Zhang, Jun Yu, Frank Eisenhaber, Xin Gao, Takashi Gojobori

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About the dark corners in the gene function space of Escherichia coli remaining without illumination by scientific literature by Erwin Tantoso, Birgit Eisenhaber, Swati Sinha, Lars Juhl Jensen, Frank Eisenhaber

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Did the early full genome sequencing of yeast boost gene function discovery? by Erwin Tantoso, Birgit Eisenhaber, Swati Sinha, Lars Juhl Jensen, Frank Eisenhaber

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PICLS with human cells is the first high throughput screening method for identifying novel compounds that extend lifespan by Mohammad Alfatah, Yizhong Zhang, Arshia Naaz, Trishia Yi Ning Cheng, Frank Eisenhaber

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Correction: Brief Overview of Bioinformatics Activities in Singapore. by Frank Eisenhaber, Chee-Keong Kwoh, See-Kiong Ng, Wing-Kin Sung, Limsoon Wong

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Iron Supplementation Delays Aging and Extends Cellular Lifespan through Potentiation of Mitochondrial Function by Jovian Lin Jing, Trishia Cheng Yi Ning, Federica Natali, Frank Eisenhaber, Mohammad Alfatah

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Brief overview of bioinformatics activities in Singapore. by Frank Eisenhaber, Chee-Keong Kwoh, See-Kiong Ng, Wing-Kin Sung, Limsoon Wong

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Uncharacterized yeast gene YBR238C, an effector of TORC1 signaling in a mitochondrial feedback loop, accelerates cellular aging via HAP4- and RMD9-dependent mechanisms by Mohammad Alfatah, Jolyn Jia Jia Lim, Yizhong Zhang, Arshia Naaz, Trishia Yi Ning Cheng, Sonia Yogasundaram, Nashrul Afiq Faidzinn, Jovian Jing Lin, Birgit Eisenhaber, Frank Eisenhaber

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Global longitudinal strain and plasma biomarkers for prognosis in heart failure complicated by diabetes: a prospective observational study by Nithin R. Iyer, Siew-Pang Chan, Oi Wah Liew, Jenny P.C. Chong, Jennifer A. Bryant, Thu-Thao Le, Chanchal Chandramouli, Patrick J. Cozzone, Frank Eisenhaber, Roger Foo, A. Mark Richards, Carolyn S.P. Lam, Martin Ugander, Calvin W-L. Chin, on behalf of the ATTRaCT investigators

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Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer by Alok K. Mishra, Tianyi Ye, Shahid Banday, Ritesh P. Thakare, Chinh Tran-To Su, Ngoc N.H. Pham, Amjad Ali, Ankur Kulshreshtha, Shreya Roy Chowdhury, Tessa M. Simone, Kai Hu, Lihua Julie Zhu, Birgit Eisenhaber, Sara K. Deibler, Karl Simin, Paul R. Thompson, Michelle A. Kelliher, Frank Eisenhaber, Sunil K. Malonia, Michael R. Green

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