Clinical implications of subclonal TP53 mutations in acute myeloid leukemia by Katharina T. Prochazka, Gudrun Pregartner, Frank G. Rücker, Ellen Heitzer, Gabriel Pabst, Albert Wölfler, Armin Zebisch, Andrea Berghold, Konstanze Döhner, Heinz Sill

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Chromothripsis is linked to TP53 alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype by Frank G. Rücker, Anna Dolnik, Tamara J. Blätte, Veronica Teleanu, Aurélie Ernst, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Konstanze Döhner, Lars Bullinger

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Integrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia by Annika C. Russ, Sandrine Sander, Sonja C. Lück, Katharina M. Lang, Marion Bauer, Frank G. Rücker, Hans A. Kestler, Richard F. Schlenk, Hartmut Döhner, Karlheinz Holzmann, Konstanze Döhner, Lars Bullinger

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Genome-wide genotyping of acute myeloid leukemia with translocation t(9;11)(p22;q23) reveals novel recurrent genomic alterations by Michael W.M. Kühn, Lars Bullinger, Stefan Gröschel, Jan Krönke, Jennifer Edelmann, Frank G. Rücker, Karina Eiwen, Peter Paschka, Verena I. Gaidzik, Karlheinz Holzmann, Richard F. Schlenk, Hartmut Döhner, Konstanze Döhner

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The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements by Sarah Grasedieck, Ariene Cabantog, Liam MacPhee, Junbum Im, Christoph Ruess, Burcu Demir, Nadine Sperb, Frank G. Rücker, Konstanze Döhner, Tobias Herold, Jonathan R. Pollack, Lars Bullinger, Arefeh Rouhi, Florian Kuchenbauer

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Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation by Sibylle Cocciardi, Anna Dolnik, Silke Kapp-Schwoerer, Frank G. Rücker, Susanne Lux, Tamara J. Blätte, Sabrina Skambraks, Jan Krönke, Florian H. Heidel, Tina M. Schnöder, Andrea Corbacioglu, Verena I. Gaidzik, Peter Paschka, Veronica Teleanu, Gudrun Göhring, Felicitas Thol, Michael Heuser, Arnold Ganser, Daniela Weber, Eric Sträng, Hans A. Kestler, Hartmut Döhner, Lars Bullinger, Konstanze Döhner

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S135: NEXT-GENERATION SEQUENCING-BASED MEASURABLE RESIDUAL DISEASE MONITORING IN ACUTE MYELOID LEUKEMIA WITH FLT3 INTERNAL TANDEM DUPLICATION TREATED WITH INTENSIVE CHEMOTHERAPY PL... by Frank G Rücker, Lars Bullinger, Sibylle Cocciardi, Sabrina Skambraks, Tamara J Luck, Daniela Weber, Isabelle Schneider, Andrea Corbacioglu, Verena I Gaidzik, Ekaterina Jahn, Nikolaus Jahn, Silke Kapp-Schwoerer, Anika Schrade, Frauke Theis, Walter Fiedler, Helmut R Salih, Gerald Wulf, Hans Salwender, Thomas Schroeder, Katharina S Götze, Thomas Kindler, Michael Lübbert, Richard F Schlenk, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Konstanze Döhner

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Refinement of the prognostic impact of somatic CEBPA bZIP domain mutations in acute myeloid leukemia: Results of the AML Study Group (AMLSG) by Frank G. Rücker, Andrea Corbacioglu, Julia Krzykalla, Sibylle Cocciardi, Claudia Lengerke, Ulrich Germing, Gerald Wulf, Maisun A. Samra, Lino L. Teichmann, Michael Lübbert, Michael W. M. Kühn, Martin Bentz, Jörg Westermann, Lars Bullinger, Verena I. Gaidzik, Annika Meid, Sophia Aicher, Frank Stegelmann, Daniela Weber, Anika Schrade, Felicitas Thol, Michael Heuser, Arnold Ganser, Axel Benner, Hartmut Döhner, Konstanze Döhner, for the German‐Austrian Acute Myeloid Leukemia Study Group (AMLSG)

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Measurable residual disease monitoring in AML with FLT3-ITD treated with intensive chemotherapy plus midostaurin by Frank G. Rücker, Lars Bullinger, Sibylle Cocciardi, Sabrina Skambraks, Tamara J. Luck, Daniela Weber, Julia Krzykalla, Ema Pozek, Isabelle Schneider, Andrea Corbacioglu, Verena I. Gaidzik, Annika Meid, Sophia Aicher, Frank Stegelmann, Anika Schrade, Frauke Theis, Walter Fiedler, Helmut R. Salih, Gerald Wulf, Hans Salwender, Thomas Schroeder, Katharina S. Götze, Michael W. M. Kühn, Michael Lübbert, Richard F. Schlenk, Axel Benner, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Konstanze Döhner

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Abstracts from the 3rd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects by Athel Cornish-Bowden, Athel Cornish-Bowden, David Rasnick, Henry H. Heng, Steven Horne, Batoul Abdallah, Guo Liu, Christine J. Ye, Mathew Bloomfield, Mark D. Vincent, C. Marcelo Aldaz, Jenny Karlsson, Anders Valind, Caroline Jansson, David Gisselsson, Jennifer A. Marshall Graves, Aleksei A. Stepanenko, Svitlana V. Andreieva, Kateryna V. Korets, Dmytro O. Mykytenko, Nataliya L. Huleyuk, Vladimir P. Baklaushev, Oksana A. Kovaleva, Vladimir P. Chekhonin, Yegor S. Vassetzky, Stanislav S. Avdieiev, Bjorn Bakker, Aaron S. Taudt, Mirjam E. Belderbos, David Porubsky, Diana C. J. Spierings, Tristan V. de Jong, Nancy Halsema, Hinke G. Kazemier, Karina Hoekstra-Wakker, Allan Bradley, Eveline S. J. M. de Bont, Anke van den Berg, Victor Guryev, Peter M. Lansdorp, Maria Colomé Tatché, Floris Foijer, Thomas Liehr, Nicolaas C. Baudoin, Joshua M. Nicholson, Kimberly Soto, Isabel Quintanilla, Jordi Camps, Daniela Cimini, M. Dürrbaum, N. Donnelly, V. Passerini, C. Kruse, B. Habermann, Z. Storchová, Daniele Mandrioli, Fiorella Belpoggi, Ellen K Silbergeld, Melissa J Perry, Rolf I. Skotheim, Marthe Løvf, Bjarne Johannessen, Andreas M. Hoff, Sen Zhao, Jonas M. SveeStrømme, Anita Sveen, Ragnhild A. Lothe, R. Hehlmann, A. Voskanyan, A. Fabarius, Alfred Böcking, Stefan Biesterfeld, Leonid Berynskyy, Christof Börgermann, Rainer Engers, Josef Dietz, A. Fritz, N. Sehgal, J. Vecerova, B. Stojkovicz, H. Ding, N. Page, C. Tye, S. Bhattacharya, J. Xu, G. Stein, J. Stein, R. Berezney, Xue Gong, Sarah Grasedieck, Julian Swoboda, Frank G. Rücker, Lars Bullinger, Jonathan R. Pollack, Fani-Marlen Roumelioti, Maria Chiourea, Christina Raftopoulou, Sarantis Gagos, Peter Duesberg, Mat Bloomfield, Sunyoung Hwang, Hans Tobias Gustafsson, Ciara O’Sullivan, Aracelli Acevedo-Colina, Xinhe Huang, Christian Klose, Andrej Schevchenko, Robert C. Dickson, Paola Cavaliere, Noah Dephoure, Eduardo M. Torres, Martha R. Stampfer, Lukas Vrba, Mark A. LaBarge, Bernard Futscher, James C. Garbe, Yi-Hong Zhou, Andrew L. Trinh, Yi-Hong Zhou, Michelle Digman

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