New Developments in Diagnosis and Management of Acquired Hemophilia and Acquired von Willebrand Syndrome by Frank W. G. Leebeek

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Identification of fibrin clot-bound plasma proteins. by Simone Talens, Frank W G Leebeek, Jeroen A A Demmers, Dingeman C Rijken

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Deep compartment models: A deep learning approach for the reliable prediction of time‐series data in pharmacokinetic modeling by Alexander Janssen, Frank W. G. Leebeek, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT study group and SYMPHONY consortium

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Emerging Concepts in Immune Thrombocytopenia by Maurice Swinkels, Maaike Rijkers, Jan Voorberg, Gestur Vidarsson, Frank W. G. Leebeek, A. J. Gerard Jansen, A. J. Gerard Jansen

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Performance related factors are the main determinants of the von Willebrand factor response to exhaustive physical exercise. by Janine E van Loon, Michelle A H Sonneveld, Stephan F E Praet, Moniek P M de Maat, Frank W G Leebeek

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Modeling Benefits, Costs, and Affordability of a Novel Gene Therapy in Hemophilia A by Renske M.T. ten Ham, Sikon M. Walker, Marta O. Soares, Geert W.J. Frederix, Frank W.G. Leebeek, Kathelijn Fischer, Michiel Coppens, Stephen J. Palmer

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Effect of genetic variation in STXBP5 and STX2 on von Willebrand factor and bleeding phenotype in type 1 von Willebrand disease patients. by Janine E van Loon, Yvonne V Sanders, Eva M de Wee, Marieke J H A Kruip, Moniek P M de Maat, Frank W G Leebeek

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Quantitative 3D microscopy highlights altered von Willebrand factor α‐granule storage in patients with von Willebrand disease with distinct pathogenic mechanisms by Maurice Swinkels, Ferdows Atiq, Petra E. Bürgisser, Johan A. Slotman, Adriaan B. Houtsmuller, Cilia deHeus, Judith Klumperman, Frank W. G. Leebeek, Jan Voorberg, Arend Jan Gerard Jansen, Ruben Bierings

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Effects of Diabetes Mellitus on Fibrin Clot Structure and Mechanics in a Model of Acute Neutrophil Extracellular Traps (NETs) Formation by Judith J. de Vries, Tamara Hoppenbrouwers, Cristina Martinez-Torres, Rezin Majied, Behiye Özcan, Mandy van Hoek, Frank W.G. Leebeek, Dingeman C. Rijken, Gijsje H. Koenderink, Moniek P.M. de Maat

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Desmopressin testing in von Willebrand disease: Lowering the burden by Jessica M. Heijdra, Ferdows Atiq, Wala Al Arashi, Quincy Kieboom, Esmee Wuijster, Karina Meijer, Marieke J. H. A. Kruip, Frank W. G. Leebeek, Marjon H. Cnossen, in collaboration with the OPTI‐CLOT Study Group

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Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease. by Shirley Uitte de Willige, Fiona M Keane, David G Bowen, Joyce J M C Malfliet, H Emma Zhang, Bharvi Maneck, Geoffrey W McCaughan, Frank W G Leebeek, Dingeman C Rijken, Mark D Gorrell

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Antithrombotic Treatment in Patients With Hemophilia: an EHA-ISTH-EAHAD-ESO Clinical Practice Guidance by Roger E.G. Schutgens, Victor Jimenez-Yuste, Miguel Escobar, Anna Falanga, Bruna Gigante, Robert Klamroth, Riitta Lassila, Frank W.G. Leebeek, Michael Makris, Tarek Owaidah, Michelle Sholzberg, Andreas Tiede, David J. Werring, H. Bart van der Worp, Jerzy Windyga, Giancarlo Castaman

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Von Willebrand Factor Multimer Densitometric Analysis: Validation of the Clinical Accuracy and Clinical Implications in Von Willebrand Disease by Johan Boender, Ferdows Atiq, Marjon H. Cnossen, Johanna G. van der Bom, Karin Fijnvandraat, Joke de Meris, Moniek P. M. de Maat, Karin P. M. van Galen, Britta A. P. Laros-van Gorkom, Karina Meijer, Jeroen Eikenboom, Frank W. G. Leebeek, for the WiN study group*

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Design of a Prospective Study on Pharmacokinetic-Guided Dosing of Prophylactic Factor Replacement in Hemophilia A and B (OPTI-CLOT TARGET Study) by Tine M.H.J. Goedhart, Laura H. Bukkems, Michiel Coppens, Karin J. Fijnvandraat, Saskia E.M. Schols, Roger E.G. Schutgens, Jeroen Eikenboom, Floor C.J.I. Heubel-Moenen, Paula F. Ypma, L. Nieuwenhuizen, K. Meijer, Frank W. G. Leebeek, Ron A.A. Mathôt, Marjon H. Cnossen

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Desmopressin for bleeding in non‐severe hemophilia A: Suboptimal use in a real‐world setting by Anne‐Fleur Zwagemaker, Fabienne R. Kloosterman, Michiel Coppens, Samantha C. Gouw, Sara Boyce, Catherine N. Bagot, Erik A. M. Beckers, Paul Brons, Giancarlo Castaman, Jeroen Eikenboom, Shannon Jackson, Marieke J. H. A. Kruip, Frank W. G. Leebeek, Karina Meijer, Laurens Nieuwenhuizen, Ingrid Pabinger, Karin Fijnvandraat, the DYNAMO Study Group

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Hepatitis C virus in hemophilia: Health‐related quality of life after successful treatment in the sixth Hemophilia in the Netherlands study by Cas J. Isfordink, Samantha C. Gouw, Erna C. vanBalen, Shermarke Hassan, Erik A. M. Beckers, Johanna G. van derBom, Michiel Coppens, Jeroen Eikenboom, Kathelijn Fischer, Louise Hooimeijer, Frank W. G. Leebeek, Frits R. Rosendaal, Saskia E. M. Schols, Cees Smit, Lize F. D. vanVulpen, Eveline P. Mauser‐Bunschoten

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Importance of Genotyping in von Willebrand Disease to Elucidate Pathogenic Mechanisms and Variability in Phenotype by Ferdows Atiq, Johan Boender, Waander L. van Heerde, Juan M. Tellez Garcia, Selene C. Schoormans, Sandy Krouwel, Marjon H. Cnossen, Britta A. P. Laros-van Gorkom, Joke de Meris, Karin Fijnvandraat, Johanna G. van der Bom, Karina Meijer, Karin P. M. van Galen, Jeroen Eikenboom, Frank W. G. Leebeek, for the WiN Study Group*

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Socioeconomic participation of persons with hemophilia: Results from the sixth hemophilia in the Netherlands study by Erna C. van Balen, Shermarke Hassan, Cees Smit, Mariette H. E. Driessens, Erik A. M. Beckers, Michiel Coppens, Jeroen C. Eikenboom, Hélène L. Hooimeijer, Frank W. G. Leebeek, Evelien P. Mauser‐Bunschoten, Lize F. D. van Vulpen, Saskia E. M. Schols, Frits R. Rosendaal, Johanna G. van der Bom, Samantha C. Gouw

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Major differences in clinical presentation, diagnosis and management of men and women with autosomal inherited bleeding disorders by F. Atiq, J.L. Saes, M.C. Punt, K.P.M. van Galen, R.E.G. Schutgens, K. Meijer, M.H. Cnossen, B.A.P. Laros-Van Gorkom, M. Peters, L. Nieuwenhuizen, M.J.H.A. Kruip, J. de Meris, J.G. van der Bom, F.J.M. van der Meer, K. Fijnvandraat, I.C. Kruis, W.L. van Heerde, H.C.J. Eikenboom, Frank W.G. Leebeek, S.E.M. Schols

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Illustrated State‐of‐the‐Art Capsules of the ISTH 2021 Congress by Sriram Krishnaswamy, Walter Ageno, Yaseen Arabi, Tiziano Barbui, Suzanne Cannegieter, Marc Carrier, Audrey C. Cleuren, Peter Collins, Laurence Panicot‐Dubois, Jane E. Freedman, Kathleen Freson, Philip Hogg, Andra H. James, Colin A. Kretz, Michelle Lavin, Frank W. G. Leebeek, Weikai Li, Coen Maas, Kellie Machlus, Michael Makris, Ida Martinelli, Leonid Medved, Marguerite Neerman‐Arbez, James S. O’Donnell, Jamie O'Sullivan, Madhvi Rajpurkar, Verena Schroeder, Paul Clinton Spiegel Jr, Simon J. Stanworth, Laura Green, Anetta Undas

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