Editorial: Defects in Regulation: How, Where and When the Immune System Can Go Wrong by Ger T. Rijkers, Carlo Riccardi, Frans G. M. Kroese

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B Cell Involvement in the Pathogenesis of Ankylosing Spondylitis by Rick Wilbrink, Anneke Spoorenberg, Gwenny M. P. J. Verstappen, Frans G. M. Kroese

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After an initial balance favoring collagen formation and mineralization, bone turnover markers return to pre-treatment levels during long-term TNF-α inhibition in patients with ank... by Mark Siderius, Anneke Spoorenberg, Frans G M Kroese, Eveline van der Veer, Suzanne Arends

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Current insights into the relationship between the gut microbiome and Sjögren’s syndrome by Taco A. van der Meulen, Frans G. M. Kroese, Hendrika Bootsma, Fred K. L. Spijkervet, Arjan Vissink

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The formation of mutated IgM memory B cells in rat splenic marginal zones is an antigen dependent process. by Jacobus Hendricks, Annie Visser, Peter M Dammers, Johannes G M Burgerhof, Nicolaas A Bos, Frans G M Kroese

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Decreased BAFF Receptor Expression and Unaltered B Cell Receptor Signaling in Circulating B Cells from Primary Sjögren’s Syndrome Patients at Diagnosis by Stefan F. H. Neys, Gwenny M. Verstappen, Hendrika Bootsma, Frans G. M. Kroese, Rudi W. Hendriks, Odilia B. J. Corneth

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Dysregulation of NF-kB in glandular epithelial cells results in Sjögren's-like features. by Xiaoyan Wang, Abeer Shaalan, Silvia Liefers, Julie Coudenys, Dirk Elewaut, Gordon B Proctor, Hendrika Bootsma, Frans G M Kroese, Sarah Pringle

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Imaging in Primary Sjögren’s Syndrome by Martha S. van Ginkel, Andor W.J.M. Glaudemans, Bert van der Vegt, Esther Mossel, Frans G.M. Kroese, Hendrika Bootsma, Arjan Vissink

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Decrease in alpha-1 antiproteinase antitrypsin is observed in primary Sjogren’s syndrome condition by Brij B. Singh, Joyce Ohm, Fredice O. Quenum Zanbede, Pooja Chauhan, Frans G. M. Kroese, Arjan Vissink, Julian L. Ambrus, Bibhuti B. Mishra

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Lack of Conventional Acinar Cells in Parotid Salivary Gland of Patient Taking an Anti-PD-L1 Immune Checkpoint Inhibitor by Sarah Pringle, Bert van der Vegt, Xiaoyan Wang, Nico van Bakelen, T. Jeroen N. Hiltermann, Fred K. L. Spijkervet, Arjan Vissink, Frans G. M. Kroese, Hendrika Bootsma

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Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca2+ signalling by Yuyang Sun, Viviane Nascimento Da Conceicao, Arun Chauhan, Pramod Sukumaran, Pooja Chauhan, Julian L. Ambrus, Arjan Vissink, Frans G. M. Kroese, Madesh Muniswamy, Bibhuti B. Mishra, Brij B. Singh

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Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients by Annie Visser, Marieke E. Doorenspleet, Marieke E. Doorenspleet, Marieke E. Doorenspleet, Niek de Vries, Niek de Vries, Fred K. L. Spijkervet, Arjan Vissink, Richard J. Bende, Hendrika Bootsma, Frans G. M. Kroese, Nicolaas A. Bos

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Immunogenicity and safety of COVID-19 vaccination in patients with primary Sjögren’s syndrome by Suzanne Arends, Frans G M Kroese, Arjan Vissink, Hendrika Bootsma, Gwenny M Verstappen, Liseth de Wolff, Annie Visser, Yannick van Sleen, Hella-Marie Heiermann, Janneke H Terpstra, Dimitri A Diavatopoulos, Marieke van der Heiden, Debbie van Baarle

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The Transcriptome of Paired Major and Minor Salivary Gland Tissue in Patients With Primary Sjögren’s Syndrome by Gwenny M. Verstappen, Lu Gao, Sarah Pringle, Erlin A. Haacke, Bert van der Vegt, Silvia C. Liefers, Vishal Patel, Yanhua Hu, Sumanta Mukherjee, Julie Carman, Laurence C. Menard, Frederik K. L. Spijkervet, Arjan Vissink, Hendrika Bootsma, Frans G. M. Kroese

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Low Mutational Burden of Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue in Patients with Primary Sjogren’s Syndrome by Johanna A. A. Bult, Jessica R. Plaça, Erlin A. Haacke, M. Martijn Terpstra, Gwenny M. Verstappen, Frederik K. L. Spijkervet, Frans G. M. Kroese, Wouter J. Plattel, Joost S. P. Vermaat, Hendrika Bootsma, Bert van der Vegt, Arjan Diepstra, Anke van den Berg, Klaas Kok, Marcel Nijland

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