Modeling Alzheimer’s disease using human cell derived brain organoids and 3D models 由 Sarah Fernandes, Sarah Fernandes, Jasmin Revanna, Jasmin Revanna, Joshua Pratt, Joshua Pratt, Nicholas Hayes, Nicholas Hayes, Maria C. Marchetto, Fred H. Gage

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Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson’s disease patients 由 Idan Rosh, Utkarsh Tripathi, Yara Hussein, Wote Amelo Rike, Jose Djamus, Boris Shklyar, Andreea Manole, Henry Houlden, Jurgen Winkler, Fred H. Gage, Shani Stern

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Upregulated ECM genes and increased synaptic activity in Parkinson’s human DA neurons with PINK1/ PRKN mutations 由 Utkarsh Tripathi, Idan Rosh, Ran Ben Ezer, Ritu Nayak, Yara Hussein, Ashwani Choudhary, Jose Djamus, Andreea Manole, Henry Houlden, Fred H. Gage, Shani Stern

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Tyro3 promotes the maturation of glutamatergic synapses 由 Sheng Miao, Lawrence Fourgeaud, Patrick G. Burrola, Shani Stern, Shani Stern, Yuhan Zhang, Kaisa E. Happonen, Sammy Weiser Novak, Fred H. Gage, Greg Lemke

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High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer 由 Tobias T. Schmidt, Carly Tyer, Preeyesh Rughani, Candy Haggblom, Jeffrey R. Jones, Xiaoguang Dai, Kelly A. Frazer, Fred H. Gage, Sissel Juul, Scott Hickey, Jan Karlseder

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Protocol for the San Diego Nathan Shock Center Clinical Cohort: a new resource for studies of human aging 由 Jeanne F Nichols, Ryan Moran, Howard J Phang, Stephanie R Heimler, Lina M Scandalis, David Wing, Daniel Moreno, Gerald S Shadel, Fred H Gage, Anthony J A Molina

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Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation 由 Tomohisa Toda, Tracy A. Bedrosian, Simon T. Schafer, Michael S. Cuoco, Sara B. Linker, Saeed Ghassemzadeh, Lisa Mitchell, Jack T. Whiteley, Nicole Novaresi, Aidan H. McDonald, Iryna S. Gallina, Hyojung Yoon, Mark E. Hester, Monique Pena, Christina Lim, Emelia Suljic, Abed AlFatah Mansour, Matthieu Boulard, Sarah L. Parylak, Fred H. Gage

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miR-124 coordinates metabolic regulators acting at early stages of human neurogenesis 由 Geurim Son, Yongwoo Na, Yongsung Kim, Ji-Hoon Son, Gregory D. Clemenson, Simon T. Schafer, Jong-Yeon Yoo, Sarah L. Parylak, Apua Paquola, Hyunsu Do, Dayeon Kim, Insook Ahn, Mingyu Ju, Chanhee S. Kang, Younghee Ju, Eunji Jung, Aidan H. McDonald, Youngjin Park, Gilhyun Kim, Se-Bum Paik, Junho Hur, Joon Kim, Yong-Mahn Han, Seung-Hee Lee, Fred H. Gage, Jong-Seo Kim, Jinju Han

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