Commentary: The landscape of transcription errors in eukaryotic cells por Bert M. Verheijen, Fred W. van Leeuwen

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Editorial: Ubiquitin and the Brain: Roles of Proteolysis in the Normal and Abnormal Nervous System por Ashok N. Hegde, Fred W. van Leeuwen

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Deposition of mutant ubiquitin in parkinsonism–dementia complex of Guam por Bert M. Verheijen, Tomoyo Hashimoto, Kiyomitsu Oyanagi, Fred W. van Leeuwen

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Dysfunction of Protein Quality Control in Parkinsonism–Dementia Complex of Guam por Bert M. Verheijen, Bert M. Verheijen, Kiyomitsu Oyanagi, Kiyomitsu Oyanagi, Fred W. van Leeuwen

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Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin por Ralf J. Braun, Cornelia Sommer, Christine Leibiger, Romina J.G. Gentier, Verónica I. Dumit, Katrin Paduch, Tobias Eisenberg, Lukas Habernig, Gert Trausinger, Christoph Magnes, Thomas Pieber, Frank Sinner, Jörn Dengjel, Fred W. van Leeuwen, Guido Kroemer, Frank Madeo

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Localization of mutant ubiquitin in the brain of a transgenic mouse line with proteasomal inhibition and its validation at specific sites in Alzheimer’s disease por Romina Jozefa Gentier, Bert M. Verheijen, Margherita eZamboni, Maartje M.A. Stroeken, Denise J.H.P. Hermes, Benno eKusters, Benno eKusters, Harry Wilhelm Maria Steinbusch, David A. Hopkins, David A. Hopkins, Fred W. Van Leeuwen

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Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast por Ralf J. Braun, Cornelia Sommer, Christine Leibiger, Romina J.G. Gentier, Verónica I. Dumit, Katrin Paduch, Tobias Eisenberg, Lukas Habernig, Gert Trausinger, Christoph Magnes, Thomas Pieber, Frank Sinner, Jörn Dengjel, Fred W. van Leeuwen, Guido Kroemer, Frank Madeo

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Altered ubiquitin signaling induces Alzheimer’s disease-like hallmarks in a three-dimensional human neural cell culture model por Inbal Maniv, Mahasen Sarji, Anwar Bdarneh, Alona Feldman, Roi Ankawa, Elle Koren, Inbar Magid-Gold, Noa Reis, Despina Soteriou, Shiran Salomon-Zimri, Tali Lavy, Ellina Kesselman, Naama Koifman, Thimo Kurz, Oded Kleifeld, Daniel Michaelson, Fred W. van Leeuwen, Bert M. Verheijen, Yaron Fuchs, Michael H. Glickman

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