The impact of COVID-19 workload on psychological distress amongst Canadian intensive care unit healthcare workers during the 1st wave of the COVID-19 pandemic: A longitudinal cohor... by Daniel Pestana, Kyra Moura, Claire Moura, Taylor Mouliakis, Frédérick D'Aragon, Jennifer L Y Tsang, Alexandra Binnie

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Retroclavicular vs Infraclavicular block for brachial plexus anesthesia: a multi-centric randomized trial by Andrés Felipe Gil Blanco, Pascal Laferrière-Langlois, David Jessop, Frédérick D’Aragon, Yanick Sansoucy, Natalie Albert, Pascal Tétreault, Pablo Echave

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Functional recovery with peripheral nerve block versus general anesthesia for upper limb surgery: a systematic review by Jennifer Héroux, Pierre-Olivier Bessette, Emilie Belley-Côté, Daphnée Lamarche, Pablo Échavé, Marie-Josée Loignon, Nicolas Patenaude, Jean-Patrice Baillargeon, Frédérick D’Aragon

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Time-course full profiling of circulating miRNAs in neurologically deceased organ donors: a proof of concept study to understand the onset of the cytokine storm by Andrée-Anne Clément, Daphnée Lamarche, Marie-Hélène Masse, Cécilia Légaré, Lee-Hwa Tai, Laurence Fleury Deland, Marie-Claude Battista, Luigi Bouchard, Frédérick D’Aragon

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Cardiac donation after circulatory determination of death: protocol for a mixed-methods study of healthcare provider and public perceptions in Canada by Jeanna Parsons Leigh, Ian Ball, Marat Slessarev, Michaël Chasse, Frédérick D'Aragon, Matthew Weiss, Maureen Meade, John Basmaji, Aimee Sarti, Kimia Honarmand, Robert Sibbald

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Pulmonary complications and mortality among COVID-19 patients undergoing a surgery: a multicentre cohort study by Alexis F Turgeon, Frédérick D'Aragon, Martin Girard, Pierre Beaulieu, Philippe Richebé, François Martin Carrier, Etienne Couture, Vincent Lecluyse, Eva Amzallag, Thanushka Panchadsaram, Stanislas Kandelman, Caroline Jodoin

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Vasopressin Use in the Support of Organ Donors: Physiological Rationale and Review of the Literature by Sofiane Ouerd, MD, MSc, Anne Julie Frenette, PharmD, PhD, David Williamson, BPharm, PhD, Karim Serri, MD, Frederick D’Aragon, MD, MSc, Daniel G. Bichet, MD, Emmanuel Charbonney, MD, PhD

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Neurologic Physiology after Removal of Therapy (NeuPaRT) study: study protocol of a multicentre, prospective, observational, pilot feasibility study of neurophysiology after withdr... by Charles Weijer, Loretta Norton, Teneille Gofton, Marat Slessarev, Michaël Chasse, John Gordon Boyd, Frédérick D'Aragon, Shane English, Maureen Meade, Sam Shemie, Sonny Dhanani, Andreas H Kramer, Jennifer Chandler, Eileen Campbell, Jeffrey Singh, Yun-Hee Choi, Maxwell J Smith, Erika Chamberlain, Nathan B Scales, Nicholas Murphy, Derek Debicki, Tadeu A Fantaneanu, Julie Kromm, Tracey C Bentall

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Sex and gender-based analysis and diversity metric reporting in acute care trials published in high-impact journals: a systematic review by Lehana Thabane, Arnav Agarwal, Valeria Raparelli, Dipayan Chaudhuri, Karen E A Burns, Emilie Belley-Cote, Frédérick D'Aragon, Louise Pilote, Vincent Issac Lau, Kimia Honarmand, David Granton, Jan O Friedrich, Vatsal Trivedi, Varuna Prakash, Daniel Wiseman, Myanca Rodrigues, Julie Reid, Benedetta Perna, Riccardo Spaggiari, Valeria Fortunato, Gianluca Risdonne, Michelle Kho, Sandra VanderKaay, Carolina Gomez-Builes, Celina Lin, Maha Al Mandhari

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Exploring the experiences and perspectives of substitute decision-makers involved in decisions about deceased organ donation: a qualitative study protocol by Dean A Fergusson, Greg Knoll, François Lauzier, Simon C Kitto, Jamie Brehaut, Justin Presseau, Ian Ball, Michaël Chasse, Karen E A Burns, Alexis F Turgeon, Frédérick D'Aragon, Jacob Crawshaw, Zack van Allen, Livia Pinheiro Carvalho, Kim Jordison, Shane English, Aimee J Sarti, Claudio Martin, Alvin Ho-ting Li, Marie-Chantal Fortin, Matthew Weiss, Maureen Meade, Pierre Marsolais, Sam Shemie, Sanabelle Zaabat, Sonny Dhanani

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Research interrupted: applying the CONSERVE 2021 Statement to a randomized trial of rehabilitation during critical illness affected by the COVID-19 pandemic by Julie C. Reid, Alex Molloy, Geoff Strong, Laurel Kelly, Heather O’Grady, Deborah Cook, Patrick M. Archambault, Ian Ball, Sue Berney, Karen E. A. Burns, Frederick D’Aragon, Erick Duan, Shane W. English, François Lamontagne, Amy M. Pastva, Bram Rochwerg, Andrew J. E. Seely, Karim Serri, Jennifer L. Y. Tsang, Avelino C. Verceles, Brenda Reeve, Alison Fox-Robichaud, John Muscedere, Margaret Herridge, Lehana Thabane, Michelle E. Kho, on behalf of the CYCLE Investigators

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Early In-Bed Cycle Ergometry With Critically Ill, Mechanically Ventilated Patients: Statistical Analysis Plan for CYCLE (Critical Care Cycling to Improve Lower Extremity Strength),... by Diane Heels-Ansdell, Laurel Kelly, Heather K O'Grady, Christopher Farley, Julie C Reid, Sue Berney, Amy M Pastva, Karen EA Burns, Frédérick D'Aragon, Margaret S Herridge, Andrew Seely, Jill Rudkowski, Bram Rochwerg, Alison Fox-Robichaud, Ian Ball, Francois Lamontagne, Erick H Duan, Jennifer Tsang, Patrick M Archambault, Avelino C Verceles, John Muscedere, Sangeeta Mehta, Shane W English, Tim Karachi, Karim Serri, Brenda Reeve, Lehana Thabane, Deborah Cook, Michelle E Kho

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Frequency of screening and SBT Technique Trial—North American Weaning Collaboration (FAST-NAWC): an update to the protocol and statistical analysis plan by Karen E. A. Burns, Myriam Lafrienier-Roula, Nicholas S. Hill, Deborah J. Cook, Andrew J. E. Seely, Bram Rochwerg, Michael Mayette, Frederick D’Aragon, John W. Devlin, Peter Dodek, Maged Tanios, Audrey Gouskos, Alexis F. Turgeon, Pierre Aslanian, Ying Tung Sia, Jeremy R. Beitler, Robert Hyzy, Gerard J. Criner, Elias Baedorf Kassis, Jennifer L. Y. Tsang, Maureen O. Meade, Janice M. Liebler, Jessica T. Y. Wong, Kevin E. Thorpe, For the Canadian Critical Care Trials Group

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Critical Care Cycling to Improve Lower Extremity Strength (CYCLE): protocol for an international, multicentre randomised clinical trial of early in-bed cycling for mechanically ven... by Avelino C Verceles, Jennifer L Y Tsang, Sangeeta Mehta, Michelle E Kho, Alexander J Molloy, Margaret S Herridge, Bram Rochwerg, Ian M Ball, Joseph R Pellizzari, Jean-Eric Tarride, Diane Heels-Ansdell, John Muscedere, Francois Lamontagne, Tim Karachi, Alison Fox-Robichaud, Shane W English, Karen E A Burns, Frédérick D'Aragon, Sue Berney, Karim Serri, Erick H Duan, Lisa Buckingham, Julie Reid, Andrew J Seely, Christopher Farley, Amy M Pastva, Heather O'Grady, Laurel Kelly, Geoff Strong, Abby H Hurd

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Calcineurin Inhibitor in NEuRoloGically deceased donors to decrease kidney delayed graft function study: study protocol of the CINERGY Pilot randomised controlled trial by Greg Knoll, Bram Rochwerg, François Lauzier, Marat Slessarev, Michaël Chasse, Karen E A Burns, Alexis F Turgeon, John Gordon Boyd, Frédérick D'Aragon, Shane English, Matthew Weiss, Maureen Meade, Sonny Dhanani, Marie-Hélène Masse, François-Martin Carrier, Steven Hanna, Andrew Healey, Simon J W Oczkowski, Anne-Julie Frenette, Anique Ducharme, Prosanto Chaudhury, Markus Selzner, Ruth Breau, Mélanie Masse, Héloïse Cardinal, Brigitte Bolduc, Caroline Lamarche, Etienne Couture, Sandra Holdsworth, Liz Bertholz, Heather Talbot, Patrick Luke, M Khaled Shamseddin, Jeffrey Zaltzman, Darin Treleaven

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Calcineurin Inhibition in Deceased Organ Donors: A Systematic Review and Meta-analysis of Preclinical Studies by Frédérick D’Aragon, MD, William Rousseau, MD, Ruth Breau, BA, Daniel Aminaei, BSc, Carole Ichai, MD, Gordon J. Boyd, MD, PhD, Karen E. A. Burns, MD, Héloïse Cardinal, MD, PhD, François-Martin Carrier, MD, Michaël Chassé, MD, PhD, Prosanto Chaudhury, MD, Sonny Dhanani, MD, Shane W. English, MD, Anne Julie Frenette, PhD, Steven Hanna, PhD, Gregory Knoll, MD, François Lauzier, MD, Simon Oczkowski, MD, Bram Rochwerg, MD, Khaled Shamseddin, MD, Marat Slessarev, MD, PhD, Darin Treleaven, MD, Alexis F. Turgeon, MD, Matthew J. Weiss, MD, Markus Selzner, MD, Maureen O. Meade, MD

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Optimal VAsopressor TitraTION in patients 65 years and older (OVATION-65): protocol and statistical analysis plan for a randomised clinical trial by Sangeeta Mehta, Bram Rochwerg, François Lauzier, Emmanuel Charbonney, Francois Lamontagne, Michaël Chasse, Marie-Claude Battista, Emilie Belley-Cote, Brian H Cuthbertson, Andreas Laupacis, Robert A Fowler, Tina Millen, Laveena Munshi, Sumesh Shah, Alexis Turgeon, David Bellemare, Eve Cloutier, Marjorie Daigle, Stéphanie Grenier, Gabrielle Guilbault, Sydney Miezitis, Rebecca Porteous, Irene Watpool, Karolina Walczak, Frédérick D’Aragon, Charles St-Arnaud, Elaine Carbonneau, Joannie Marchand, Marie-Hélène Masse, Fatna Benettaib, Dounia Boumahni, Marie-Ève Cantin, Ali Ghamraoui, Martine Lebrasseur, Maya Salame, Navjot Kaur, Nicole Marinoff, Guillaume Leblanc, Mary Elizabeth Wilcox, Ruxandra Pinto, Michael Mayette, Marc-André Leclair, Hector Quiroz Martinez, Brian Grondin-Beaudoin, Yannick Poulin, Andrew J E Seely, Édouard Botton, Dian Cohen, Neill K J Adhikari, Neill KJ Adhikari, Lauren Griffith, Scott Halpern, Louise Robert-Petit, Marie-Ève Thibault, François-Michel Boisvert, Lee Hwa Tai, Jean-Luc Parent, Xavier Roucou, Hector Quiroz-Martinez, Line Côté, Marilène Ladouceur, Noémie Turcotte, Andrew Seely, Andre Carlos Amaral, Damon C Scales, Wael Mohammed, Charles Francoeur, Olivier Costerousse, Isabelle St-Hilaire, Jeffrey Singh

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Benzodiazepine-Free Cardiac Anesthesia for Reduction of Postoperative Delirium (B-Free): A Protocol for a Multi-centre Randomized Cluster Crossover Trial by Jessica Spence, MD, PhD, Emilie Belley-Côté, MD, PhD, Eric Jacobsohn, MBChB, MPHE, Shun Fu Lee, PhD, Frederick D’Aragon, MD, MSc, FRCPC, Michael Avidan, MBBCh, C. David Mazer, MD, Nicolas Rousseau-Saine, MD, Raja Rajamohan, MD, Kane Pryor, MD, Rael Klein, MBBCh, Edmund (Chong-How) Tan, MD, Matthew Cameron, MDCM, MPH, Emily Di Sante, MA, Erin DeBorba, MSc, Mary Mustard, BScN, MN, Etienne Couture, MD, Raffael Zamper, MD, PhD, Michael Law, MD, George Djaiani, MD, Tarit Saha, MBBS, Stephen Choi, MD, MSc, Peter Hedlin, MD, PhD, Ryan Pikaluk, MD, Wing Ying Lam, MD, MPH, Alain Deschamps, MD, PhD, Richard Whitlock, MD, PhD, Braden Dulong, MD, P.J. Devereaux, MD, PhD, Chris Beaver, P.Eng, Shelley Kloppenburg, BSW, Simon Oczkowski, MD, MHSc, William Finlay McIntyre, MD, PhD, Matthew McFarling, MD, Andre Lamy, MD, MHSc, Jessica Vincent, MSc, Stuart Connolly, MD, MSc

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Inhaled Volatiles for Status Asthmaticus, Epilepsy, and Difficult Sedation in Adult ICU and PICU: A Systematic Review by Kevin Gorsky, MD, Sean Cuninghame, MD, Kesikan Jayaraj, RN, Marat Slessarev, MD, PhD, FRCPC, Conall Francoeur, MD, Davinia E. Withington, BM, FRCA, MRCP(UK), Jennifer Chen, Brian H. Cuthbertson, MBBS, PhD, Claudio Martin, MD, Martin Chapman, MD, FRCPC, Saptharishi Lalgudi Ganesan, MBBS, MD, DM, FACNS, Nicole McKinnon, MD, PhD, Angela Jerath, MD, MSc, FANZCA, FRCPC, on behalf of the SAVE-ICU Study Investigators, Martin Chapman, Damon Scales, Julie Nardi, Beth Linseman, Phil Lau, Boris Yakubov, Eily Shaw, Francois Carrier, Emmanuel Charbonney, Michaël Chassé, Martin Girard, Antoine Halwagi, Guillaume Plourde, Han Ting Wang, Frédérick D’Aragon, Maxime Tissot-Therrien, François Lamontagne, Dominique Bérard, Yiorgos Alexandros Cavayas, Martin Albert, Francis Bernard, Karim Serri, David Williamson, Virginie Williams, Patricia Martinez Barrios, Sabrina Araujo De Franca, Etienne J. Couture, Adreanne Côté, Mathieu Simon, Pierre-Alexis Lépine, Dave Gleeton, John Basmaji, Marat Slessarev, Ahmed Hegazy, Tracey Bentall, Eileen Campbell, Michelle Stephens, Tim Winterburn, Roupen Hatzakorzian, Kosar Khwaja, Peter Goldberg, Jason Shahin, Jeremy Richard Grushka, Jonathan Hooper, Sherissa Microys, Hilary Meggison, David Leilipovitz, Jessica Haines, Irene Watpool, Rebecca Porteous, Stephanie Dunster, Sylvie Bourbonnais, Ewan Goligher, Lorenzo Del Sorbo, Niall Ferguson, Philip Graham, Michael Long, Tina Yan, Denise Morris, Maria Kobylecky, Hesham Abdelhady, Tina Romagnuolo, Bourke Tillman, Ian Randall, Elizabeth Wilcox, Michael Jacka, Oleksa Rewa, Vincent Lau, Sean Bagshaw, Nadia Baig

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STRIVE pilot trial: a protocol for a multicentre pragmatic internal pilot randomised controlled trial of Structured TRaining to Improve fitness in a Virtual Environment (STRIVE) be... by Alan Forster, Nicola Edwards, Jean Wong, Frances Chung, Luke T Lavallée, François Lellouche, Monica Taljaard, Tim Ramsay, James Paul, Michael Schmidt, Manoj M Lalu, Jason Chui, Stephen Choi, Shelly Au, Richard Hall, Harsha Shanthanna, Hance Clarke, Stuart Mccluskey, Marcin Wasowicz, Karim Ladha, Angela Jerath, Daniel Sellers, Thomas Schricker, Roupen Hatzakorzian, Stephen Kowalski, James Green, Daniel I McIsaac, Guillaume Martel, Merrick Zwarenstein, Sylvain Boet, Kednapa Thavorn, I Singh, Karim Abdulla, Margaret L McNeely, Jessica Spence, Emilie Belley-Cote, Julie Hallet, Herman Sehmbi, Tarit Saha, David Rosen, George Wang, Connor Brenna, Tien Le, Ruth Graham, Husein Moloo, Hilary Grocott, Kelly Vogt, Gary Dobson, Faisal Siddiqui, Alexis Turgeon, Frédérick D’Aragon, Martin Girard, Brian Cuthbertson, Timothy Jackson, Ian Gilron, Norman Buckley, Andy Liu, Naveed Siddiqui, Leyla Baghirzada, Stephen Yang, William Wang, James Kim, Neil Goldenberg, Nicolas Beaudet, Dean Fergusson, Keyvan Karkouti, Jordan Tarshis, Colin McCartney, Vishal Uppal, Christopher Prabhakar, Derek Dillane, Jordan Leitch, Ramiro Arellano, Joel Parlow, George Djaiani, Lilia Kaustov, Peter Hedlin, Andrew Milne, Heather McDonald, David Boyle, Isabelle Raiche, Lara Williams, Emily Hladkowicz, Sylvain Gagne, Celena Scheede-Bergdahl, C David Mazer, Justyna Bartoszko, Chelsia Gillis, Michael Law, Edmond Li, Sarah Sinasac, Roberta DiDonato, Rene Martin, Thomas Hemmerling, Beverley Orser, Pierre Drolet, Vatsal Trivedi, Jason McVicar, Daniel Bainbridge, Pierre Beaulieu, Faraj Abdallah, Naheed Jivraj, Heather Pierce, Hema Bagry, Rakesh Sondekoppam, Christian Lehmann, John Fuller, Derek Roberts, Homer Yang, Stuart Wright, Michael Jacka, Curtis Nickel, Rodney Breau, Daenis Camire, Nidhi Charan, Louise Sun, Susan Lee, Rachel Khadaroo, Amanda Meliambro, Jennifer O’Brien, Renée El-Gabalawy, Daniel Trottier, Keely Barnes, Laura Boland, Karina Branje, Rosaleen Chun, Antoine Eskander, Joanne Hutton, John Joanisse, Cameron Love, Thomas Mutter, Sudhir Nagpal, Pablo Serrano, Carl van Walraven, Ilun Yang, Bryan Glezerson, Sylvie Aucoin, Rebecca Auer, Gregory Bryson, Dolores McKeen, Tyrone Harrison, Puneeta Tandon, Michael Verret, Sarah McMullen, William Beaubien-Souligny, Duminda Nalaka Wijeysundera, Samantha Russell, Victor Neira, Matthias Görges, Catherine Duclos, Etienne Couture, Diem Tran, Stephan Schwarz, Alana Flexman, Terri Sun, Michelle Mozel, Olivier Royer, Gurlavine Kidd, Tyler Chesney, Humberto R Vigil, Mary Farnand, Juliette Gaudreault, Bhagya Lakshmi Ramappa Tahasildar, Julian Mansour, William Scott Beattie, André Denault, Kathryn Sparrow, Jamal Alkadri, Saleh Al-Nahdi, Siniana Avramescu, Jonathan Bailey, Alex Bak, Gabriele Baldinii, Jean-Marie Bamvita, Jillian Banfield, Michael Bautista, Jean Beaubien, Gianluca Bertolizio, Guillaume Bousquet-Dion, Scott Brudney, Neville Burke, Jean Bussières, Matthew Cameron, Francois M Carrier, Françoise Chagnon, Anton Chau, Marshall Cheng, Gilles Chiniara, Janice Chisholm, Michelle Chiu, Chris Christodoulou, Pieter de Jager, Megan Deck, Ainsley Decker, Alain Deschamps, Daniel Dubois, Laura Duggan, Tristan Dumbarton, Deborah DuMerton Shore, Kaylene Duttchen, Darcie Earle, Marie-Pierre Gagne, Nicole Gibson, Andres-Felipe Gil, Talha Gondal, Daniel Gottesman, Alexander Gregory, Alexander Grunfeld, Gregory Hare, Jennifer Héroux, Orlando Hung, Janny Ke, Brent Kennedy, Brad Kerr, Margot Klemmer, Wing Lam, Danielle Lapierre, Jean-Sebastian Lebon, Vincent Lecluyse, Alexandre Lefebvre, Nagappa Mahes, William McKay, Perseus Missirlis, Glenio Mizubuti, Peter Moliner, Corentin Monfort, Janice Montbriand, Maliha Muneer, Allana Munro, Bhanu Nalla, Wayne Nates, David Neilpovitz, Angela Neufeld, Angélica Ostiguy, Charles Overbeek, Jean P Gelinas, Gilles Plourde, Jeremy Pridham, Mateen Raazi, Saifee Rashiq, Ravi Jayas, Ravi Taneja, Rebecca Grey, Tracey Rice, Richard N Merchant, David Roach, Roanne Preston, Ron Ree, Ronald George, Jean-Dennis Roy, Rudy Noppens, Ryan McGinn, Ryan Ramos, Sonia Sampson, Corey Sawchuk, Seyed Mahdi Sedighi, Surita Sidhu, Stephanie Sobotie, Sabri Soussi, Summer Sukh Brar, Varun Suresh, Vanessa Sweet, Linda Szabo, Edmond Tan, Mullein Thorleifson, Andrea Todd, Victor Tran, Dianshi Wang, Louie Wang, Geoff Warden, Kim Wong, Vincent Wourms, Cynthia Yarnold, Doreen Yee

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