satmut_utils: a simulation and variant calling package for multiplexed assays of variant effect by Ian Hoskins, Song Sun, Atina Cote, Frederick P. Roth, Can Cenik

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Characterizing glucokinase variant mechanisms using a multiplexed abundance assay by Sarah Gersing, Thea K. Schulze, Matteo Cagiada, Amelie Stein, Frederick P. Roth, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

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Quantitative proteomics and biological activity of extracellular vesicles engineered to express SARS‐CoV‐2 spike protein by Dongsic Choi, Nargis Khan, Laura Montermini, Nadim Tawil, Brian Meehan, Dae‐Kyum Kim, Frederick P. Roth, Maziar Divangahi, Janusz Rak

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Yeast-Based Genetic Interaction Analysis of Human Kinome by Jae-Hong Kim, Yeojin Seo, Myungjin Jo, Hyejin Jeon, Won-Ha Lee, Nozomu Yachie, Quan Zhong, Marc Vidal, Frederick P. Roth, Kyoungho Suk

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Quantitative analysis of protein interaction network dynamics in yeast by Albi Celaj, Ulrich Schlecht, Justin D Smith, Weihong Xu, Sundari Suresh, Molly Miranda, Ana Maria Aparicio, Michael Proctor, Ronald W Davis, Frederick P Roth, Robert P St.Onge

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Benchmarking computational variant effect predictors by their ability to infer human traits by Daniel R. Tabet, Da Kuang, Megan C. Lancaster, Roujia Li, Karen Liu, Jochen Weile, Atina G. Coté, Yingzhou Wu, Robert A. Hegele, Dan M. Roden, Frederick P. Roth

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An Atlas of Variant Effects to understand the genome at nucleotide resolution by Douglas M. Fowler, David J. Adams, Anna L. Gloyn, William C. Hahn, Debora S. Marks, Lara A. Muffley, James T. Neal, Frederick P. Roth, Alan F. Rubin, Lea M. Starita, Matthew E. Hurles

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Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact by Melissa A Chiasson, Nathan J Rollins, Jason J Stephany, Katherine A Sitko, Kenneth A Matreyek, Marta Verby, Song Sun, Frederick P Roth, Daniel DeSloover, Debora S Marks, Allan E Rettie, Douglas M Fowler

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A resource of human coronavirus protein-coding sequences in a flexible, multipurpose Gateway Entry clone collection by Benjamin Weller, Chung-Wen Lin, Oxana Pogoutse, Mayra Sauer, Nora Marin-de la Rosa, Alexandra Strobel, Veronika Young, Jennifer J Knapp, Ashyad Rayhan, Claudia Falter, Dae-Kyum Kim, Frederick P Roth, Pascal Falter-Braun

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Systematic exploration of synergistic drug pairs by Murat Cokol, Hon Nian Chua, Murat Tasan, Beste Mutlu, Zohar B Weinstein, Yo Suzuki, Mehmet E Nergiz, Michael Costanzo, Anastasia Baryshnikova, Guri Giaever, Corey Nislow, Chad L Myers, Brenda J Andrews, Charles Boone, Frederick P Roth

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A comprehensive map of human glucokinase variant activity by Sarah Gersing, Matteo Cagiada, Marinella Gebbia, Anette P. Gjesing, Atina G. Coté, Gireesh Seesankar, Roujia Li, Daniel Tabet, Jochen Weile, Amelie Stein, Anna L. Gloyn, Torben Hansen, Frederick P. Roth, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

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Leveraging cancer mutation data to inform the pathogenicity classification of germline missense variants. by Bushra Haque, David Cheerie, Amy Pan, Meredith Curtis, Thomas Nalpathamkalam, Jimmy Nguyen, Celine Salhab, Bhooma Thiruvahindrapuram, Jade Zhang, Madeline Couse, Taila Hartley, Michelle M Morrow, E Magda Price, Susan Walker, David Malkin, Frederick P Roth, Gregory Costain

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Minimum information and guidelines for reporting a multiplexed assay of variant effect by Melina Claussnitzer, Victoria N. Parikh, Alex H. Wagner, Jeremy A. Arbesfeld, Carol J. Bult, Helen V. Firth, Lara A. Muffley, Alex N. Nguyen Ba, Kevin Riehle, Frederick P. Roth, Daniel Tabet, Benedetta Bolognesi, Andrew M. Glazer, Alan F. Rubin

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Systematic analysis of bypass suppression of essential genes by Jolanda van Leeuwen, Carles Pons, Guihong Tan, Zi Yang Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone

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A comprehensive two-hybrid analysis to explore the Legionella pneumophila effector–effector interactome by Harley O'Connor Mount, Malene L. Urbanus, Dayag Sheykhkarimli, Atina G. Coté, Florent Laval, Georges Coppin, Nishka Kishore, Roujia Li, Kerstin Spirohn-Fitzgerald, Morgan O. Petersen, Jennifer J. Knapp, Dae-Kyum Kim, Jean-Claude Twizere, Michael A. Calderwood, Marc Vidal, Frederick P. Roth, Alexander W. Ensminger

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Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics by J Javier Díaz‐Mejía, Albi Celaj, Joseph C Mellor, Atina Coté, Attila Balint, Brandon Ho, Pritpal Bansal, Fatemeh Shaeri, Marinella Gebbia, Jochen Weile, Marta Verby, Anna Karkhanina, YiFan Zhang, Cassandra Wong, Justin Rich, D'Arcy Prendergast, Gaurav Gupta, Sedide Öztürk, Daniel Durocher, Grant W Brown, Frederick P Roth

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A framework for exhaustively mapping functional missense variants by Jochen Weile, Song Sun, Atina G Cote, Jennifer Knapp, Marta Verby, Joseph C Mellor, Yingzhou Wu, Carles Pons, Cassandra Wong, Natascha van Lieshout, Fan Yang, Murat Tasan, Guihong Tan, Shan Yang, Douglas M Fowler, Robert Nussbaum, Jesse D Bloom, Marc Vidal, David E Hill, Patrick Aloy, Frederick P Roth

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An inter‐species protein–protein interaction network across vast evolutionary distance by Quan Zhong, Samuel J Pevzner, Tong Hao, Yang Wang, Roberto Mosca, Jörg Menche, Mikko Taipale, Murat Taşan, Changyu Fan, Xinping Yang, Patrick Haley, Ryan R Murray, Flora Mer, Fana Gebreab, Stanley Tam, Andrew MacWilliams, Amélie Dricot, Patrick Reichert, Balaji Santhanam, Lila Ghamsari, Michael A Calderwood, Thomas Rolland, Benoit Charloteaux, Susan Lindquist, Albert‐László Barabási, David E Hill, Patrick Aloy, Michael E Cusick, Yu Xia, Frederick P Roth, Marc Vidal

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Author Correction: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism by Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

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Pooled‐matrix protein interaction screens using Barcode Fusion Genetics by Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth

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