CRISPR/Cas9 System as a Valuable Genome Editing Tool for Wine Yeasts with Application to Decrease Urea Production by Ileana Vigentini, Marinella Gebbia, Alessandra Belotti, Roberto Foschino, Frederick P. Roth, Frederick P. Roth, Frederick P. Roth, Frederick P. Roth

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Characterizing ABC-Transporter Substrate-Likeness Using a Clean-Slate Genetic Background by Artem Sokolov, Stephanie Ashenden, Stephanie Ashenden, Nil Sahin, Nil Sahin, Richard Lewis, Nurdan Erdem, Elif Ozaltan, Andreas Bender, Frederick P. Roth, Frederick P. Roth, Frederick P. Roth, Murat Cokol, Murat Cokol, Murat Cokol, Murat Cokol

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satmut_utils: a simulation and variant calling package for multiplexed assays of variant effect by Ian Hoskins, Song Sun, Atina Cote, Frederick P. Roth, Can Cenik

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Protein domain-level landscape of cancer-type-specific somatic mutations. by Fan Yang, Evangelia Petsalaki, Thomas Rolland, David E Hill, Marc Vidal, Frederick P Roth

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Characterizing glucokinase variant mechanisms using a multiplexed abundance assay by Sarah Gersing, Thea K. Schulze, Matteo Cagiada, Amelie Stein, Frederick P. Roth, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

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RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. by Kohila Mahadevan, Hui Zhang, Abdalla Akef, Xianying A Cui, Serge Gueroussov, Can Cenik, Frederick P Roth, Alexander F Palazzo

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Quantitative proteomics and biological activity of extracellular vesicles engineered to express SARS‐CoV‐2 spike protein by Dongsic Choi, Nargis Khan, Laura Montermini, Nadim Tawil, Brian Meehan, Dae‐Kyum Kim, Frederick P. Roth, Maziar Divangahi, Janusz Rak

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MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect by Daniel Esposito, Jochen Weile, Jay Shendure, Lea M. Starita, Anthony T. Papenfuss, Frederick P. Roth, Douglas M. Fowler, Alan F. Rubin

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Confirmation of organized modularity in the yeast interactome. by Nicolas Bertin, Nicolas Simonis, Denis Dupuy, Michael E Cusick, Jing-Dong J Han, Hunter B Fraser, Frederick P Roth, Marc Vidal

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Interpreting metabolomic profiles using unbiased pathway models. by Rahul C Deo, Luke Hunter, Gregory D Lewis, Guillaume Pare, Ramachandran S Vasan, Daniel Chasman, Thomas J Wang, Robert E Gerszten, Frederick P Roth

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Modeling the impact of drug interactions on therapeutic selectivity by Zohar B. Weinstein, Nurdan Kuru, Szilvia Kiriakov, Adam C. Palmer, Ahmad S. Khalil, Paul A. Clemons, Muhammad H. Zaman, Frederick P. Roth, Murat Cokol

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Yeast-Based Genetic Interaction Analysis of Human Kinome by Jae-Hong Kim, Yeojin Seo, Myungjin Jo, Hyejin Jeon, Won-Ha Lee, Nozomu Yachie, Quan Zhong, Marc Vidal, Frederick P. Roth, Kyoungho Suk

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Genome analysis reveals interplay between 5'UTR introns and nuclear mRNA export for secretory and mitochondrial genes. by Can Cenik, Hon Nian Chua, Hui Zhang, Stefan P Tarnawsky, Abdalla Akef, Adnan Derti, Murat Tasan, Melissa J Moore, Alexander F Palazzo, Frederick P Roth

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Quantitative analysis of protein interaction network dynamics in yeast by Albi Celaj, Ulrich Schlecht, Justin D Smith, Weihong Xu, Sundari Suresh, Molly Miranda, Ana Maria Aparicio, Michael Proctor, Ronald W Davis, Frederick P Roth, Robert P St.Onge

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A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase by Song Sun, Jochen Weile, Marta Verby, Yingzhou Wu, Yang Wang, Atina G. Cote, Iosifina Fotiadou, Julia Kitaygorodsky, Marc Vidal, Jasper Rine, Pavel Ješina, Viktor Kožich, Frederick P. Roth

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Benchmarking computational variant effect predictors by their ability to infer human traits by Daniel R. Tabet, Da Kuang, Megan C. Lancaster, Roujia Li, Karen Liu, Jochen Weile, Atina G. Coté, Yingzhou Wu, Robert A. Hegele, Dan M. Roden, Frederick P. Roth

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An Atlas of Variant Effects to understand the genome at nucleotide resolution by Douglas M. Fowler, David J. Adams, Anna L. Gloyn, William C. Hahn, Debora S. Marks, Lara A. Muffley, James T. Neal, Frederick P. Roth, Alan F. Rubin, Lea M. Starita, Matthew E. Hurles

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Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact by Melissa A Chiasson, Nathan J Rollins, Jason J Stephany, Katherine A Sitko, Kenneth A Matreyek, Marta Verby, Song Sun, Frederick P Roth, Daniel DeSloover, Debora S Marks, Allan E Rettie, Douglas M Fowler

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A resource of human coronavirus protein-coding sequences in a flexible, multipurpose Gateway Entry clone collection by Benjamin Weller, Chung-Wen Lin, Oxana Pogoutse, Mayra Sauer, Nora Marin-de la Rosa, Alexandra Strobel, Veronika Young, Jennifer J Knapp, Ashyad Rayhan, Claudia Falter, Dae-Kyum Kim, Frederick P Roth, Pascal Falter-Braun

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Systematic exploration of synergistic drug pairs by Murat Cokol, Hon Nian Chua, Murat Tasan, Beste Mutlu, Zohar B Weinstein, Yo Suzuki, Mehmet E Nergiz, Michael Costanzo, Anastasia Baryshnikova, Guri Giaever, Corey Nislow, Chad L Myers, Brenda J Andrews, Charles Boone, Frederick P Roth

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