Systematic Comparison of CRISPR and shRNA Screens to Identify Essential Genes Using a Graph-Based Unsupervised Learning Model by Yulian Ding, Connor Denomy, Andrew Freywald, Yi Pan, Franco J. Vizeacoumar, Frederick S. Vizeacoumar, Fang-Xiang Wu

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Synthetic lethal interactions of DEAD/H-box helicases as targets for cancer therapy by Ananna Bhadra Arna, Hardikkumar Patel, Ravi Shankar Singh, Frederick S. Vizeacoumar, Anthony Kusalik, Andrew Freywald, Franco J. Vizeacoumar, Yuliang Wu

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Homoharringtonine demonstrates a cytotoxic effect against triple-negative breast cancer cell lines and acts synergistically with paclitaxel by Riley Plett, Paul Mellor, Stephanie Kendall, S. Austin Hammond, Aren Boulet, Kristine Plaza, Frederick S. Vizeacoumar, Franco J. Vizeacoumar, Deborah H. Anderson

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A Drug Repurposing Screen Identifies Fludarabine Phosphate as a Potential Therapeutic Agent for N-MYC Overexpressing Neuroendocrine Prostate Cancers by Hussain Elhasasna, Raymond Khan, Kalpana K. Bhanumathy, Frederick S. Vizeacoumar, Prachi Walke, Maricris Bautista, Dinesh K. Dahiya, Vincent Maranda, Hardikkumar Patel, Amrutha Balagopal, Nezeka Alli, Anand Krishnan, Andrew Freywald, Franco J. Vizeacoumar

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hnRNP A1 dysfunction alters RNA splicing and drives neurodegeneration in multiple sclerosis (MS) by Hannah E. Salapa, Patricia A. Thibault, Cole D. Libner, Yulian Ding, Joseph-Patrick W. E. Clarke, Connor Denomy, Catherine Hutchinson, Hashim M. Abidullah, S. Austin Hammond, Landon Pastushok, Frederick S. Vizeacoumar, Michael C. Levin

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An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer by Noam Auslander, Chelsea E Cunningham, Behzad M Toosi, Emily J McEwen, Keren Yizhak, Frederick S Vizeacoumar, Sreejit Parameswaran, Nir Gonen, Tanya Freywald, Kalpana K Bhanumathy, Andrew Freywald, Franco J Vizeacoumar, Eytan Ruppin

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MEMO1 binds iron and modulates iron homeostasis in cancer cells by Natalia Dolgova, Eva-Maria E Uhlemann, Michal T Boniecki, Frederick S Vizeacoumar, Anjuman Ara, Paria Nouri, Martina Ralle, Marco Tonelli, Syed A Abbas, Jaala Patry, Hussain Elhasasna, Andrew Freywald, Franco J Vizeacoumar, Oleg Y Dmitriev

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Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR by Glinton Hanover, Frederick S. Vizeacoumar, Sara L. Banerjee, Raveena Nair, Renuka Dahiya, Ana I. Osornio-Hernandez, Alain Morejon Morales, Tanya Freywald, Juha P. Himanen, Behzad M. Toosi, Nicolas Bisson, Franco J. Vizeacoumar, Andrew Freywald

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A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities by Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O'Brien, Brenda Andrews, Charles Boone, Jason Moffat

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