Refractory systemic onset juvenile idiopathic arthritis: current challenges and future perspectives nork William G. Ambler, Kabita Nanda, Karen Brandt Onel, Susan Shenoi

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205 Lymphatic dysfunction in lupus photosensitivity nork Babak Mehrara, Scott Rodeo, Theresa T Lu, Noa Schwartz, William G Ambler, Jin Yeon Shin, Rahgu Kataru, Camila Carballo

Shunt dependency after aneurysmal subarachnoid haemorrhage and influence of admission hyperglycaemia nork I.C. Hostettler, N. Lange, N. Schwendinger, T. Hirle, G. Ambler, S. Frangoulis, D. Trost, J. Gempt, K. Kreiser, B. Meyer, C. Winter, M. Wostrack

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The importance of transdiagnostic symptom level assessment to understanding prognosis for depressed adults: analysis of data from six randomised control trials nork C. O’Driscoll, J. E. J. Buckman, E. I. Fried, R. Saunders, Z. D. Cohen, G. Ambler, R. J. DeRubeis, S. Gilbody, S. D. Hollon, T. Kendrick, D. Kessler, G. Lewis, E. Watkins, N. Wiles, S. Pilling

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802 Lymphatic dysfunction in lupus contributes to cutaneous photosensitivity and lymph node B cell responses nork Babak Mehrara, Scott Rodeo, Doruk Erkan, Ecem Sevim, Theresa T Lu, Noa Schwartz, William G Ambler, Mir Howlander, Madhavi Latha S Chalasani, Ethan S Seltzer, JiHyun Sim, Jinyeon Shin, Dragos Dasoveanu, Camila B Carballo, Salma Siddique, Raghu P Kataru

1204 Improving lymphatic function to reduce B cell responses in lupus nork Babak Mehrara, Scott Rodeo, Doruk Erkan, Ecem Sevim, Theresa T Lu, Noa Schwartz, William G Ambler, Madhavi Latha S Chalasani, Ethan S Seltzer, JiHyun Sim, Jinyeon Shin, Dragos Dasoveanu, Camila B Carballo, Salma Siddique, Raghu P Kataru, Mir Howlader

Comparison of wearable device measured mobility with patient-reported mobility during peri-operative recovery following radical cystectomy nork P. Khetrapal, J.W.F. Catto, N. Williams, G. Ambler, R. Sarpong, M.S. Khan, R. Thurairaja, M.E.L. Tan, A. Feber, S. Dixon, N. Vasdev, L. Goodwin, J. McGrath, P. Charlesworth, E. Rowe, A. Koupparis, C. Brew-Graves, J.D. Kelly

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The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus nork Thomas Morgan Li, Victoria Zyulina, Ethan S Seltzer, Marija Dacic, Yurii Chinenov, Andrea R Daamen, Keila R Veiga, Noa Schwartz, David J Oliver, Pamela Cabahug-Zuckerman, Jose Lora, Yong Liu, William D Shipman, William G Ambler, Sarah F Taber, Karen B Onel, Jonathan H Zippin, Mehdi Rashighi, James G Krueger, Niroshana Anandasabapathy, Inez Rogatsky, Ali Jabbari, Carl P Blobel, Peter E Lipsky, Theresa T Lu

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404 The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus nork Peter E Lipsky, Yong Liu, Niroshana Anandasabapathy, Mehdi Rashighi, Jose Lora, Yurii Chinenov, Ali Jabbari, Carl P Blobel, Thomas M Li, William D Shipman, Theresa T Lu, Noa Schwartz, David J Oliver, Keila R Veiga, James G Krueger, William G Ambler, Andrea R Daamen, Karen B Onel, Ethan S Seltzer, Pamela Zuckerman, Victoria Zyulina, Marija Dacic, Sarah F Taber, Jonathan H Zippin, Inez Rogatsky

COVIDTrach: a prospective cohort study of mechanically ventilated patients with COVID-19 undergoing tracheostomy in the UK nork A Thompson, S Wilkinson, N Kumar, G Wong, J Smith, F Franco, P Smith, A Wilson, S Ghosh, S Shepherd, A Kumar, R Brown, D Williams, M Griffiths, J Sen, M Roberts, A McGrath, D Kumar, A Walker, A Gupta, N Sharma, P Shah, M Kumar, H Jones, P Paul, I Gonzalez, A Shah, V Srinivasan, M Kelly, P Surda, K Valchanov, S Saha, R Bentley, C Hall, J Ng, C Pearce, R Harris, H Wilson, N Amin, J Phillips, D Park, C Jennings, L Wren, B McGrath, D Walker, J Ahmed, S Menon, N Jain, R Mistry, E Jackson, W Rutherford, E France, S Mahalingam, C Hogan, A Burns, T Exall, J Rodrigues, C Xie, M Rouhani, E Paramasivam, A WILLIAMSON, K STEELE, D Dawson, S Linton, M Cameron, S Biswas, S Hodges, J Collier, J Collins, S Bennett, T Ali, N Bhatti, S Suresh, J Williamson, G Ambler, C Cook, D Baker, J Bates, J Blair, P Mukherjee, A Howard, B Cosway, M Anwar, S Fang, S Meghji, H Griffiths, M Keil, F GREEN, K Hussain, A Schache, C Lockie, S Winter, J Westwood, A Hormis, P Ward, C Walker, G Sandhu, T Davies, A Lloyd, L Linhartova, C SPENCER, A Courtney, L Bates, T Martín, T Tatla, L Ritchie, P Gill, S Shannon, A Arora, R Pinto, H Turner, J Whittaker, E Warner, L Leach, A Menon, J Higginson, G Warner, A Balfour, F Cooper, A Li, S Berry, R Gohil, M Celinski, J McEwan, E Riley, S Webster, I Ahmad, M Idle, K Jolly, S Burrows, S Parmar, B Morris, A Arya, S Mustafa, E Tam, D Chakravarty, M De, A Daudia, B Tehan, R Temple, J Broad, P Andrews, D Pennell, C Smart, R D’Souza, P Praveen, DJ Lin, M Osborne, A Coombs, T Hunt, M Singer, C Smyth, R Saha, G Walton, P Bishop, U Sheikh, R O'Brien, R Bhandari, A Rovira, S Sanyal, E Yeung, A Tse, N Lawrence, P Stimpson, H Saeed, K Fan, M Ashcroft, T Jacob, J Hadley, K Goodwin, Z Abdi, D Nair, B Hill, D Whitmore, N Macartney, P Sykes, N Mercer, R Sykes, S Siddiq, Nick JI Hamilton, AGM Schilder, MM George, GM Jama, J Goulder, C Schilling, S Laha, MA Birchall, NS Tolley, P Nankivell, O Breik, P Pracy, J Osher, C Huppa, P Stenhouse, F Ryba, EK Bhargava, D Ranford, A Takhar, C Tornari, M Verkerk, C Al-Yaghchi, M Jaafar, N Cereceda-Monteoliva, A Holroyd, K Ghufoor, H O'Mahony, H Drewery, A Mulcahy, T Magos, I Balasundaram, M Heliotis, A Loizidou, D York, R Exley, KA Solanki, P Kirticumar, A Shirazian, Y Bhatt, R Natt, N Banga, K Dhadwal, I Ekpemi, R Roplekar-Bance, N Glibbery, K Karamali, T Munroe-Gray, P Sethukumar, R Vasanthan, H Lee-Six, B Misztal, S Millington, M Musalia, A Cardozo, M Dunbobbin, S Shahidi, M Chachlani, J Fussey, M Misurati, S Ashok, H Aboulgheit, S Khwaja, R Anmolsingh, B Al-Dulaimy, E Omakobia, T Browning, L Lignos, P Twose, J Heyman, D Kathwadia, T Hwara, O Judd, W Parker, TP Davis, T Stubington, H Koumoullis, E Willcocks, L Skelly, G Dempsey, K Liatsikos, B Borgatta, A Glossop, V Politidis, D Dhariwal, A Kara, G Tattersall, W Udall, P Kirkland, J Staufenberg, H Buglass, NW Wahid, A Amlani, P Deutsch, K Markham, O Barker, A Easthope, S Glaze, D Bondin, D Thorley, K Kapoor, S Sirajuddin, F van Damme, O Mattoo, E Kershaw, S Dewhurst, S Blakeley, C Chivers, L Lindsey, R Glore, H Cunniffe, D Moult, D Zolger, J Bakmanidis, S Kandiah, A Pericleous, R Sheikh, U Nagalotimath, E El-Tabal, S Ghaffar, M Dallison, E Leakey, O Sanders, A Gomati, L Moir, CB Groba, C Davies-Husband, N Seymour, R Lovett, J Lunn, A Armson, K Hilliard, S Ladan, P Tsirevelou, V Ratnam, A Muddaiah, J Coakes, R Borg, A Tsagkovits, O Mulla, N Stobbs, D Pratap, Z Ghani, J Rocke, S Snape, A Hassaan, S Beckett, R Siau, C Lamont, C Blore, D Zakai, R Moorthy, P Bothma, A Syndercombe, N Keates, M Junaid, T Antonio, A Vijendren, V Venkatachalam, M Lechner, D Chandrasekharan, J Whiteside, S Dennis, A Eldahshan, H Paw, M Colomo-Gonzalez, N Mani, B Ranganathan, N Amiruddin, A Sladkowski, AK Abou-Foul, S Kishwan, P Naredla, A Al-Ajami, S Okhovat, E Carey, N Vallabh, A. Alatsatianos, R Townsley

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