Testing sensitivity to cd30 targeting via brentuximab vedotin in multiple myeloma by E. La Spina, F. Puglisi, A. Barbato, C. Giallongo, D. Tibullo, G.A. Palumbo, F. Di Raimondo, A. Romano

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P1070: NAVITOCLAX MONOTHERAPY IN PATIENTS WITH MYELOFIBROSIS PREVIOUSLY TREATED WITH JAK-2 INHIBITORS: SAFETY AND TOLERABILITY by V. Pullarkat, A. Cruz-Chacon, S. Gangatharan, A. Melnyk, G. A. Palumbo, M. Bellini, S. K. Tantravahi, Q. Qin, J. Potluri, P. Vachhani

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P870: DEFINING A NOVEL FUNCTION FOR THE POST-TRANSLATIONAL MODIFICATION UFMYLATION IN THE ADAPTIVE RESPONSE TO ARGININE DEPRIVATION IN MULTIPLE MYELOMA by A. Romano, G. Scandura, C. Giallongo, E. La Spina, A. Barbato, D. Tibullo, K. Todoerti, A. Neri, G. A. Palumbo, F. Di Raimondo

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PB2279: REDUCED ABSOLUTE COUNT OF MONOCYTES IN PATIENTS CARRYING HEMATOLOGICAL NEOPLASMS AND SARS-COV2 BREAKTHROUGH INFECTION by A. Romano, C. Conticello, S. Filetti, A. Bulla, A. Chiarenza, V. Del Fabro, S. Leotta, U. Markovic, G. Motta, M. Parisi, F. Stagno, G. A. Palumbo, F. Di Raimondo

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P59 ACTIVE TREATMENT AND LOW IGM ARE ASSOCIATED WITH INFERIOR SARS-COV-2 SPIKE ANTIBODY RESPONSE TO THREE DOSES OF COVID-19 RNA VACCINATION IN PATIENTS WITH MULTIPLE MYELOMA by A. Duminuco, A. Romano, D. Leotta, E. La Spina, D. Cambria, A. Bulla, V. Del Fabro, D. Tibullo, C. Giallongo, G.A. Palumbo, C. Conticello, F. Di Raimondo

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P01 LACTATE TRAFFICKING INHIBITION RESTORES SENSITIVITY TO PROTEASOME INHIBITHORS AND ORCHESTRATES IMMUNOMICROENVIRONMENT IN MULTIPLE MYELOMA by C. Giallongo, T. Zuppelli, G. Scandura, E. La Spina, I. Dulcamare, D. Cambria, S. Giallongo, A. Romano, N. Parrinello, V. Del Fabro, M. Aguennoz, G. Li Volti, G.A. Palumbo, F. Di Raimondo, D. Tibullo

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P731: INTERPLAY BETWEEN INFLAMMATION AND EPIGENETICS IN TUMOR REPROGRAMMING OF MESENCHYMAL STROMAL CELLS (MSCS) IN MYELODYSPLASTIC SYNDROMES (MDS) by C. Giallongo, I. Dulcamare, D. Tibullo, D. Pieragostino, M. C. Cufaro, M. A. Amorini, G. Lazzarino, A. Romano, G. Scandura, T. Zuppelli, M. Di Rosa, A. Duminuco, G. Broggi, R. Caltabiano, R. Floresti, R. Motterlini, F. Di Raimondo, G. A. Palumbo

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P02 ARGININE DEPRIVATION INDUCES ACQUISITION OF A SENESCENT PHENOTYPE AND FAVORS GENOMIC INSTABILITY IN MULTIPLE MYELOMA PLASMACELLS by A. Romano, G. Scandura, C. Giallongo, E. La Spina, S. Giallongo, L. Longhitano, T. Zuppelli, I. Dulcamare, N. L. Parrinello, F. Polito, R. Oteri, M. Aguennouz, N. Vicario, A. M. Amorini, V. Del Fabro, C. Conticello, G. Li Volti, G. A. Palumbo, D. Tibullo, F. Di Raimondo

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P535: UPDATES FROM ITALIAN MULTICENTER REAL-LIFE EXPERIENCE ON CPX-351 THERAPY IN YOUNG PATIENTS (<60 YEARS OLD). by B. Garibaldi, M. Franciosa, F. Pilo, D. Menotti, V. Cardinali, L. Brunetti, E. A. Martino, E. Vigna, I. Tanasi, A. Duminuco, C. Maugeri, M. S. Parisi, P. F. Fiumara, E. Mauro, M. Gentile, M. P. Martelli, D. Capelli, C. Romani, S. Galimberti, G. A. Palumbo, F. Di Raimondo, C. Vetro

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MacroH2A1.1 as a crossroad between epigenetics, inflammation and metabolism of mesenchymal stromal cells in myelodysplastic syndromes by C. Giallongo, I. Dulcamare, S. Giallongo, A. Duminuco, D. Pieragostino, M. C. Cufaro, A. M. Amorini, G. Lazzarino, A. Romano, N. Parrinello, M. Di Rosa, G. Broggi, R. Caltabiano, M. Caraglia, M. Scrima, L. S. Pasquale, M. S. Tathode, G. Li Volti, R. Motterlini, F. Di Raimondo, D. Tibullo, G. A. Palumbo

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P1010: RUXOLITINIB IN MYELODEPLETIVE MYELOFIBROSIS: RESPONSE, TOXICITY, AND OUTCOME by F. Palandri, D. Bartoletti, M. Breccia, G. Auteri, E. M. Elli, M. M. Trawinska, N. Polverelli, M. Tiribelli, G. Benevolo, A. Iurlo, A. Tieghi, F. H. Heidel, G. Caocci, E. Beggiato, G. Binotto, F. Cavazzini, M. Miglino, C. Bosi, M. Crugnola, M. Bocchia, B. Martino, N. Pugliese, A. D. Romagnoli, C. Mazzoni, L. Scaffidi, A. Isidori, D. Cattaneo, M. Krampera, F. Pane, D. Cilloni, G. Semenzato, R. M. Lemoli, A. Cuneo, E. Abruzzese, N. Vianelli, M. Cavo, M. Bonifacio, G. A. Palumbo

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