P719: EFFICACY AND SAFETY OF BOSUTINIB IN LATER-LINE PATIENTS WITH CHRONIC MYELOID LEUKEMIA: A SUB-ANALYSIS FROM THE PHASE 4 BYOND TRIAL by C. Gambacorti-Passerini, T. H. Brümmendorf, T. Ernst, E. Leip, S. Purcell, A. Viqueira, F. J. Giles, G. Rosti, A. Hochhaus

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S152: SETD2/H3K36ME3 DEFICIENCY SUSTAINS GENOMIC INSTABILITY AND ENHANCES CLONOGENIC POTENTIAL OF CHRONIC MYELOID LEUKEMIA (CML) PROGENITORS by M. Mancini, S. De Santis, C. Monaldi, S. Bruno, F. Castagnetti, G. Gugliotta, A. Iurlo, M. Cerrano, S. Galimberti, S. Balducci, F. Stagno, G. Rosti, M. Cavo, S. Soverini

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Hyper-activation of Aurora kinase a-polo-like kinase 1-FOXM1 axis promotes chronic myeloid leukemia resistance to tyrosine kinase inhibitors by M. Mancini, S. De Santis, C. Monaldi, L. Bavaro, M. Martelli, F. Castagnetti, G. Gugliotta, G. Rosti, M. A. Santucci, G. Martinelli, M. Cavo, S. Soverini

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P1706: CLINICAL UTILITY OF ONLINE MONITORING OF PATIENT-REPORTED SYMPTOMS IN NEWLY DIAGNOSED PATIENTS WITH CHRONIC MYELOID LEUKEMIA IN REAL-LIFE PRACTICE by F. Efficace, F. Cottone, B. Yanez, F. Castagnetti, G. Caocci, M. Bonifacio, A. Patriarca, I. Capodanno, M. C. Miggiano, M. Tiribelli, M. Breccia, L. Luciano, V. Giai, A. Iurlo, E. Abruzzese, C. Fava, G. Rosti, J. Cortes, V. Kota, M. Vignetti, D. Cella

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P707: DOSE MODIFICATION DYNAMICS OF PONATINIB IN PATIENTS WITH CHRONIC-PHASE CHRONIC MYELOID LEUKEMIA (CP-CML) FROM THE PACE AND OPTIC TRIALS by J. Apperley, H. Kantarjian, M. Deininger, E. Abruzzese, J. Cortes, C. Chuah, D. J. DeAngelo, J. DiPersio, A. Hochhaus, J. Lipton, F. Nicolini, J. Pinilla-Ibarz, D. Rea, G. Rosti, P. Rousselot, M. Mauro, N. Shah, M. Talpaz, A. Vorog, X. Ren, E. Jabbour

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S156: INTERNATIONAL, PROSPECTIVE STUDY COMPARING NILOTINIB VERSUS IMATINIB WITH EARLY SWITCH TO NILOTINIB TO OBTAIN SUSTAINED TREATMENT-FREE REMISSION IN PATIENTS WITH WITH CHRONIC... by F. Pane, F. Castagnetti, L. Luciano, A. Russo Rossi, E. Abruzzese, R. Bassan, G. Binotto, G. Caocci, G. Cimino, P. Fazi, A. Gozzini, M. Lunghi, R. Marasca, B. Martino, M. Bonifacio, F. Cavazzini, F. Paoloni, G. Saglio, S. Sica, A. Tafuri, D. Vallisa, M. Vignetti, P. Westerweel, G. Rosti, M. Breccia

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P698: BOSUTINIB DOSE OPTIMIZATION IN THE SECOND-LINE TREATMENT OF ELDERLY CML PATIENTS: EXTENDED 3-YEAR FOLLOW-UP AND FINAL RESULTS OF THE BEST STUDY by F. Castagnetti, M. Bocchia, E. Abruzzese, I. Capodanno, M. Bonifacio, G. Rege Cambrin, M. Crugnola, G. Binotto, C. Elena, A. Lucchesi, M. Bergamaschi, F. Albano, L. Luciano, F. Sorà, F. Lunghi, F. Stagno, M. Cerrano, A. Iurlo, A. R. Scortechini, S. Leonetti Crescenzi, R. Spadano, E. Trabacchi, M. Lunghi, G. Spinosa, D. Ferrero, D. Rapezzi, M. Ladetto, L. Nocilli, G. Gugliotta, M. Iezza, M. Cavo, G. Saglio, F. Pane, G. Rosti

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Treatment discontinuation following low-dose TKIs in 248 chronic myeloid leukemia patients: Updated results from a campus CML real-life study by A. Iurlo, D. Cattaneo, D. Cattaneo, D. Consonni, F. Castagnetti, M. C. Miggiano, G. Binotto, M. Bonifacio, G. Rege-Cambrin, M. Tiribelli, F. Lunghi, A. Gozzini, P. Pregno, E. Abruzzese, I. Capodanno, C. Bucelli, M. Pizzuti, S. Artuso, M. Iezza, E. Scalzulli, G. La Barba, A. Maggi, S. Russo, C. Elena, A. R. Scortechini, A. Tafuri, R. Latagliata, G. Caocci, M. Bocchia, S. Galimberti, L. Luciano, C. Fava, R. Foà, G. Saglio, G. Rosti, M. Breccia

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