1248 Myeloid cells contribution is key to reproduce CRS pathophysiology induced by T cell engagers in BRGSF-HIS model by Gaëlle Martin, Fabiane Sônego, Yacine Cherifi, Kader Thiam, Perrine Martin-Jeantet, Alexis Gonon

1110 Cell depleting agents assessment in preclinical models by Gaëlle Martin, Fabiane Sônego, Yacine Cherifi, Kader Thiam, Angela Pappalardo, Perrine Martin-Jeantet, Alexis Gonon

MT1-MMP directs force-producing proteolytic contacts that drive tumor cell invasion by Robin Ferrari, Gaëlle Martin, Oya Tagit, Alan Guichard, Alessandra Cambi, Raphaël Voituriez, Stéphane Vassilopoulos, Philippe Chavrier

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14 Novel CD3 epsilon humanized N-terminal epitope model for assessment of efficacy of T-cell engagers by Gaëlle Martin, Fabiane Sônego, Audrey Beringer, Chloé Beuraud, Yacine Cherifi, Alexandre Fraichard, Patricia Isnard-Petit, Kader Thiam

908 Humanized model for assessment of therapies targeting either lymphoid or myeloid compartment: enhanced evaluation of clinical relevancy & translatability by Charles Dumontet, Gaëlle Martin, Chloé Beuraud, Yacine Cherifi, Alexandre Fraichard, Patricia Isnard-Petit, Kader Thiam, Angus Sinclair, Poonam Yakkundi, Florence Renart-Depontieu, Morgane Denis, Léa Magadoux, Elsa Kress, Ludovic Bourre, Dean Campbell, Astrid Doerner

782-D Systemic delivery of novel, allosteric STING agonist CRD3874-SI leads to robust anti-cancer activity by generating pro-inflammatory Type I IFN signals while blocking proton c... by Ciara Kelly, Gaëlle Martin, Fabiane Sônego, Kader Thiam, Angela Pappalardo, Anuj Singh, Monali Banerjee, Sandip Middya, Ritesh Shrivastava, Anindita Middya, Nagaswamy Mane, Nidhi Rawat, Thanilsana Soram, Debjani Chakraborty, Rajib Ghosh, Rubeena Rais Mansuri, Dharmendra Yadav, Anuj Gautam, Kavita Puniya, David Pryde, Sourav Basu, Perrine Martin-Jeantet, Arjun Surya