Combined burden and functional impact tests for cancer driver discovery using DriverPower por Shuai, Shimin, Gallinger, Steven, Stein, Lincoln

Ligazón do recurso

Liquidity analysis and management / por 249283 Gallinger, George W., Healey, P. Basil

Differential gene expression profile reveals deregulation of pregnancy specific β1 glycoprotein 9 early during colorectal carcinogenesis por Salahshor, S, Goncalves, J, Chetty, R, Gallinger, S, Woodgett, JR

Intraductal papillary mucinous neoplasm of the pancreas in a patient with attenuated familial adenomatous polyposis. por Chetty, R, Salahshor, S, Bapat, B, Berk, T, Croitoru, M, Gallinger, S

Activation of Notch signaling in human colon adenocarcinoma. por Reedijk, M, Odorcic, S, Zhang, H, Chetty, R, Tennert, C, Dickson, B, Lockwood, G, Gallinger, S, Egan, SE

MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer. por Hitchins, M, Williams, R, Cheong, K, Halani, N, Lin, V, Packham, D, Ku, S, Buckle, A, Hawkins, N, Burn, J, Gallinger, S, Goldblatt, J, Kirk, J, Tomlinson, I, Scott, R, Spigelman, A, Suter, C, Martin, D, Suthers, G, Ward, R

Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer. por Whiffin, N, Dobbins, SE, Hosking, F, Palles, C, Tenesa, A, Wang, Y, Farrington, S, Jones, A, Broderick, P, Campbell, H, Newcomb, P, Casey, G, Conti, D, Schumacher, F, Gallinger, S, Lindor, N, Hopper, J, Jenkins, M, Dunlop, MG, Tomlinson, I, Houlston, R

A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants. por Theodoratou, E, Campbell, H, Tenesa, A, Houlston, R, Webb, E, Lubbe, S, Broderick, P, Gallinger, S, Croitoru, E, Jenkins, M, Win, A, Cleary, S, Koessler, T, Pharoah, P, Küry, S, Bézieau, S, Buecher, B, Ellis, N, Peterlongo, P, Offit, K, Aaltonen, L, Enholm, S, Lindblom, A, Zhou, X, Tomlinson, I

A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants por Theodoratou, E, Campbell, H, Tenesa, A, Houlston, R, Webb, E, Lubbe, S, Broderick, P, Gallinger, S, Croitoru, E, Jenkins, M, Win, A, Cleary, S, Koessler, T, Pharoah, P, Küry, S, Bézieau, S, Buecher, B, Ellis, N, Peterlongo, P, Offit, K, Aaltonen, L, Enholm, S, Lindblom, A, Zhou, X, Tomlinson, I

COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. por Tomlinson, I, Dunlop, M, Campbell, H, Zanke, B, Gallinger, S, Hudson, T, Koessler, T, Pharoah, P, Niittymäki, I, Niittymäkix, I, Tuupanen, S, Tuupanenx, S, Aaltonen, L, Hemminki, K, Lindblom, A, Försti, A, Sieber, O, Lipton, L, van Wezel, T, Morreau, H, Wijnen, J, Devilee, P, Matsuda, K, Nakamura, Y, Castellví-Bel, S

Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variati... por Carvajal-Carmona, L, Cazier, J, Jones, A, Howarth, K, Broderick, P, Pittman, A, Dobbins, S, Tenesa, A, Farrington, S, Prendergast, J, Theodoratou, E, Barnetson, R, Conti, D, Newcomb, P, Hopper, J, Jenkins, M, Gallinger, S, Duggan, D, Campbell, H, Kerr, D, Casey, G, Houlston, R, Dunlop, M, Tomlinson, I

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. por Whiffin, N, Hosking, F, Farrington, S, Palles, C, Dobbins, SE, Zgaga, L, Lloyd, A, Kinnersley, B, Gorman, M, Tenesa, A, Broderick, P, Wang, Y, Barclay, E, Hayward, C, Martin, L, Buchanan, D, Win, A, Hopper, J, Jenkins, M, Lindor, N, Newcomb, P, Gallinger, S, Conti, D, Schumacher, F, Casey, G

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. por Wolpin, B, Rizzato, C, Kraft, P, Kooperberg, C, Petersen, G, Wang, Z, Arslan, A, Beane-Freeman, L, Bracci, P, Buring, J, Canzian, F, Duell, E, Gallinger, S, Giles, G, Goodman, G, Goodman, P, Jacobs, E, Kamineni, A, Klein, A, Kolonel, L, Kulke, M, Li, D, Malats, N, Olson, S, Risch, H

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. por Tomlinson, I, Carvajal-Carmona, L, Dobbins, SE, Tenesa, A, Jones, A, Howarth, K, Palles, C, Broderick, P, Jaeger, E, Farrington, S, Lewis, A, Prendergast, J, Pittman, A, Theodoratou, E, Olver, B, Walker, M, Penegar, S, Barclay, E, Whiffin, N, Martin, L, Ballereau, S, Lloyd, A, Gorman, M, Lubbe, S, Howie, B, Marchini, J, Ruiz-Ponte, C, Fernandez-Rozadilla, C, Castells, A, Carracedo, A, Castellvi-Bel, S, Duggan, D, Conti, D, Cazier, J, Campbell, H, Sieber, O, Lipton, L, Gibbs, P, Martin, N, Montgomery, G, Young, J, Baird, P, Gallinger, S, Newcomb, P, Hopper, J, Jenkins, M, Aaltonen, L, Kerr, D, Cheadle, J, Pharoah, P, Casey, G, Houlston, R, Dunlop, MG

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis por May-Wilson, S, Sud, A, Law, PJ, Palin, K, Tuupanen, S, Gylfe, A, Hänninen, UA, Cajuso, T, Tanskanen, T, Kondelin, J, Kaasinen, E, Sarin, AP, Eriksson, JG, Rissanen, H, Knekt, P, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Mecklin, JP, Al-Tassan, NA, Palles, C, Farrington, SM, Timofeeva, MN, Meyer, BF, Wakil, SM, Campbell, H, Smith, CG, Idziaszczyk, S, Maughan, TS, Fisher, D, Kerr, R, Kerr, D, Passarelli, MN, Figueiredo, JC, Buchanan, DD, Win, AK, Hopper, JL, Jenkins, MA, Lindor, NM, Newcomb, PA, Gallinger, S, Conti, D, Schumacher, F, Casey, G, Aaltonen, LA, Cheadle, JP, Tomlinson, IP, Dunlop, MG, Houlston, RS

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer por Jarvis, D, Mitchell, J, Law, P, Palin, K, Tuupanen, S, Gylfe, A, Hänninen, U, Cajuso, T, Tanskanen, T, Kondelin, J, Kaasinen, E, Sarin, A, Kaprio, J, Eriksson, J, Rissanen, H, Knekt, P, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Järvinen, H, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Meklin, J, Al-Tassan, N, Palles, C, Martin, L, Barclay, E, Farrington, S, Timofeeva, M, Meyer, B, Wakil, S, Campbell, H, Smith, C, Idziaszczyk, S, Maughan, T, Kaplan, R, Kerr, R, Kerr, D, Buchanan, D, Win, A, Hopper, J, Jenkins, M, Lindor, M, Newcomb, P, Gallinger, S, Conti, D, Schumacher, F, Casey, G, Taipale, J, Aaltonen, L, Cheadle, J, Dunlop, M, Tomlinson, I, Houlston, R

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci por Tanskanen, T, van den Berg, L, Välimäki, N, Aavikko, M, Ness-Jensen, E, Hveem, K, Wettergren, Y, Lindskog, E, Tõnisson, N, Metspalu, A, Silander, K, Orlando, G, Law, PJ, Tuupanen, S, Gylfe, AE, Hänninen, UA, Cajuso, T, Kondelin, J, Sarin, AP, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Järvinen, H, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Mecklin, JP, Al-Tassan, NA, Palles, C, Martin, L, Barclay, E, Tenesa, A, Farrington, SM, Timofeeva, MN, Meyer, BF, Wakil, SM, Campbell, H, Smith, CG, Idziaszczyk, S, Maughan, TS, Kaplan, R, Kerr, R, Kerr, D, Buchanan, DD, Win, AK, Hopper, J, Jenkins, MA, Newcomb, PA, Gallinger, S, Conti, D, Schumacher, FR, Casey, G, Cheadle, JP, Dunlop, MG, Tomlinson, IP, Houlston, RS, Palin, K, Aaltonen, LA

An absolute risk model to identify individuals at elevated risk for pancreatic cancer in the general population por Klein, A, Lindström, S, Mendelsohn, J, Steplowski, E, Arslan, A, Bueno-De-Mesquita, H, Fuchs, C, Gallinger, S, Gross, M, Helzlsouer, K, Holly, E, Jacobs, E, Lacroix, A, Li, D, Mandelson, M, Olson, S, Petersen, G, Risch, H, Stolzenberg-Solomon, R, Zheng, W, Amundadottir, L, Albanes, D, Allen, N, Bamlet, W, Boutron-Ruault, M, Buring, J, Bracci, P, Canzian, F, Clipp, S, Cotterchio, M, Duell, E, Elena, J, Gaziano, J, Giovannucci, E, Goggins, M, Hallmans, G, Hassan, M, Hutchinson, A, Hunter, D, Kooperberg, C, Kurtz, R, Liu, S, Overvad, K, Palli, D, Patel, A, Rabe, K, Shu, X, Slimani, N, Tobias, G, Trichopoulos, D, Van Den Eeden, S, Vineis, P, Virtamo, J, Wactawski-Wende, J, Wolpin, B, Yu, H, Yu, K, Zeleniuch-Jacquotte, A, Chanock, S, Hoover, R, Hartge, P, Kraft, P

Telomere structure and maintenance gene variants and risk of five cancer types por Karami, S, Han, Y, Pande, M, Cheng, I, Rudd, J, Pierce, BL, Nutter, EL, Schumacher, FR, Kote-Jarai, Z, Lindstrom, S, Witte, JS, Fang, S, Han, J, Kraft, P, Hunter, DJ, Song, F, Hung, RJ, McKay, J, Gruber, SB, Chanock, SJ, Risch, A, Shen, H, Haiman, CA, Boardman, L, Ulrich, CM, Casey, G, Peters, U, Olama, A, Berchuck, A, Berndt, SI, Bezieau, S, Brennan, P, Brenner, H, Brinton, L, Caporaso, N, Chan, AT, Chang-Claude, J, Christiani, DC, Cunningham, JM, Easton, D, Eeles, RA, Eisen, T, Gala, M, Gallinger, SJ, Gayther, SA, Goode, EL, Grönberg, H, Henderson, BE, Houlston, R, Joshi, AD, Küry, S, Landi, MT, Le Marchand, L, Muir, K, Newcomb, PA, Permuth-Wey, J, Pharoah, P, Phelan, C, Potter, JD, Ramus, SJ, Risch, H, Schildkraut, J, Slattery, ML, Song, H, Wentzensen, N, White, E, Wiklund, F, Zanke, BW, Sellers, TA, Zheng, W, Chatterjee, N, Amos, CI, Doherty, JA, GECCO and the GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI, and TRICL

Association analyses identify 31 new risk loci for colorectal cancer susceptibility por Law, PJ, Timofeeva, M, Fernandez-Rozadilla, C, Broderick, P, Studd, J, Fernandez-Tajes, J, Farrington, S, Svinti, V, Palles, C, Orlando, G, Sud, A, Holroyd, A, Penegar, S, Theodoratou, E, Vaughan-Shaw, P, Campbell, H, Zgaga, L, Hayward, C, Campbell, A, Harris, S, Deary, IJ, Starr, J, Gatcombe, L, Pinna, M, Briggs, S, Martin, L, Jaeger, E, Sharma-Oates, A, East, J, Leedham, S, Arnold, R, Johnstone, E, Wang, H, Kerr, D, Kerr, R, Maughan, T, Kaplan, R, Al-Tassan, N, Palin, K, Hänninen, UA, Cajuso, T, Tanskanen, T, Kondelin, J, Kaasinen, E, Sarin, A-P, Eriksson, JG, Rissanen, H, Knekt, P, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Mecklin, J-P, Buchanan, DD, Win, A-K, Hopper, J, Jenkins, ME, Lindor, NM, Newcomb, PA, Gallinger, S, Duggan, D, Casey, G, Hoffmann, P, Nöthen, MM, Jöckel, K-H, Easton, DF, Pharoah, PDP, Peto, J, Canzian, F, Swerdlow, A, Eeles, RA, Kote-Jarai, Z, Muir, K, Pashayan, N, Practical Consortium, Harkin, A, Allan, K, McQueen, J, Paul, J, Iveson, T, Saunders, M, Butterbach, K, Chang-Claude, J, Hoffmeister, M, Brenner, H, Kirac, I, Matošević, P, Hofer, P, Brezina, S, Gsur, A, Cheadle, JP, Aaltonen, LA, Tomlinson, I, Houlston, RS, Dunlop, MG