Rapid isolation of respiring skeletal muscle mitochondria using nitrogen cavitation by Awais Z. Younis, Gareth G. Lavery, Mark Christian, Craig L. Doig

Get full text

Alterations in metabolic flux in migraine and the translational relevance by Olivia Grech, Matilde Sassani, Gisela Terwindt, Gareth G. Lavery, Susan P. Mollan, Alexandra J. Sinclair

Get full text

Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid[S] by Carlos A. Penno, Stuart A. Morgan, Anna Vuorinen, Daniela Schuster, Gareth G. Lavery, Alex Odermatt

Get full text

The Role of Metabolism in Migraine Pathophysiology and Susceptibility by Olivia Grech, Susan P. Mollan, Benjamin R. Wakerley, Daniel Fulton, Gareth G. Lavery, Alexandra J. Sinclair

Get full text

Local glucocorticoid synthesis regulates house dust mite-induced airway hypersensitivity in mice by Verena M. Merk, Truong San Phan, Truong San Phan, Alice Wiedmann, Rowan S. Hardy, Gareth G. Lavery, Thomas Brunner

Get full text

The Impact of Slice Interval and Equation on the Accuracy of Magnetic Resonance Image Estimation of Quadriceps Muscle Volume in End Stage Liver Disease by Jonathan I. Quinlan, Jonathan I. Quinlan, Clare Jones, Emma Bissonnette, Amritpal Dhaliwal, Amritpal Dhaliwal, Felicity Williams, Felicity Williams, Felicity Williams, Surabhi Choudhary, Leigh Breen, Leigh Breen, Leigh Breen, Gareth G. Lavery, Gareth G. Lavery, Gareth G. Lavery, Matthew J. Armstrong, Matthew J. Armstrong, Ahmed M. Elsharkawy, Ahmed M. Elsharkawy, Janet M. Lord, Janet M. Lord, Janet M. Lord, Carolyn A. Greig, Carolyn A. Greig, Carolyn A. Greig

Get full text

PARP1 mediated PARylation contributes to myogenic progression and glucocorticoid transcriptional response by Arnold Tan, Awais Z. Younis, Alexander Evans, Jade V. Creighton, Clare Coveny, David J. Boocock, Craig Sale, Gareth G. Lavery, Amanda S. Coutts, Craig L. Doig

Get full text

Global Deletion of 11β-HSD1 Prevents Muscle Wasting Associated with Glucocorticoid Therapy in Polyarthritis by Justine M. Webster, Michael S. Sagmeister, Chloe G. Fenton, Alex P. Seabright, Yu-Chiang Lai, Simon W. Jones, Andrew Filer, Mark S. Cooper, Gareth G. Lavery, Karim Raza, Ramon Langen, Rowan S. Hardy

Get full text

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion [version 2; peer review: 2 approved] by Lucy A. Oakey, Rachel S. Fletcher, Yasir S. Elhassan, David M. Cartwright, Craig L. Doig, Antje Garten, Alpesh Thakker, Oliver D. K. Maddocks, Tong Zhang, Daniel A. Tennant, Christian Ludwig, Gareth G. Lavery

Get full text

Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin by Beom Jun Kim, Noo Ri Lee, Chung Hyeok Lee, Young Bin Lee, Sung Jay Choe, Solam Lee, Hyun Jee Hwang, Eunjung Kim, Gareth G. Lavery, Kyong-Oh Shin, Kyungho Park, Eung Ho Choi

Get full text

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells by Rachel S. Fletcher, Joanna Ratajczak, Craig L. Doig, Lucy A. Oakey, Rebecca Callingham, Gabriella Da Silva Xavier, Antje Garten, Yasir S. Elhassan, Philip Redpath, Marie E. Migaud, Andrew Philp, Charles Brenner, Carles Canto, Gareth G. Lavery

Get full text

Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction by Craig L. Doig, Agnieszka E. Zielinska, Rachel S. Fletcher, Lucy A. Oakey, Yasir S. Elhassan, Antje Garten, David Cartwright, Silke Heising, Ahmed Alsheri, David G. Watson, Cornelia Prehn, Jerzy Adamski, Daniel A. Tennant, Gareth G. Lavery

Get full text

11β-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation by Chloe G Fenton, Ana Crastin, Claire S Martin, Saicharan Suresh, Isabella Montagna, Bismah Hussain, Amy J Naylor, Simon W Jones, Morten S Hansen, Caroline M Gorvin, Maria Price, Andrew Filer, Mark S Cooper, Gareth G Lavery, Karim Raza, Rowan S Hardy

Get full text

Evaluation of the mechanisms of sarcopenia in chronic inflammatory disease: protocol for a prospective cohort study by Amritpal Dhaliwal, Felicity R. Williams, Jonathan I. Quinlan, Sophie L. Allen, Carolyn Greig, Andrew Filer, Karim Raza, Subrata Ghosh, Gareth G. Lavery, Philip N. Newsome, Surabhi Choudhary, Leigh Breen, Matthew J. Armstrong, Ahmed M. Elsharkawy, Janet M. Lord

Get full text

Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice by Daniela Nasteska, Federica Cuozzo, Katrina Viloria, Elspeth M. Johnson, Alpesh Thakker, Rula Bany Bakar, Rebecca L. Westbrook, Jonathan P. Barlow, Monica Hoang, Jamie W. Joseph, Gareth G. Lavery, Ildem Akerman, James Cantley, Leanne Hodson, Daniel A. Tennant, David J. Hodson

Get full text

The Effect of Ex Vivo Human Serum from Liver Disease Patients on Cellular Protein Synthesis and Growth by Sophie L. Allen, Alex P. Seabright, Jonathan I. Quinlan, Amritpal Dhaliwal, Felicity R. Williams, Nicholas H. F. Fine, David J. Hodson, Matthew J. Armstrong, Ahmed M. Elsharkaway, Carolyn A. Greig, Yu-Chiang Lai, Janet M. Lord, Gareth G. Lavery, Leigh Breen

Get full text

Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension by Connar S.J. Westgate, Hannah F. Botfield, Zerin Alimajstorovic, Andreas Yiangou, Mark Walsh, Gabrielle Smith, Rishi Singhal, James L. Mitchell, Olivia Grech, Keira A. Markey, Daniel Hebenstreit, Daniel A. Tennant, Jeremy W. Tomlinson, Susan P. Mollan, Christian Ludwig, Ildem Akerman, Gareth G. Lavery, Alexandra J. Sinclair

Get full text

Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion by Katrina Viloria, Daniela Nasteska, Linford J.B. Briant, Silke Heising, Dean P. Larner, Nicholas H.F. Fine, Fiona B. Ashford, Gabriela da Silva Xavier, Maria Jiménez Ramos, Annie Hasib, Federica Cuozzo, Jocelyn E. Manning Fox, Patrick E. MacDonald, Ildem Akerman, Gareth G. Lavery, Christine Flaxman, Noel G. Morgan, Sarah J. Richardson, Martin Hewison, David J. Hodson

Get full text

LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells by Federica Cuozzo, Katrina Viloria, Ali H. Shilleh, Daniela Nasteska, Charlotte Frazer-Morris, Jason Tong, Zicong Jiao, Adam Boufersaoui, Bryan Marzullo, Daniel B. Rosoff, Hannah R. Smith, Caroline Bonner, Julie Kerr-Conte, Francois Pattou, Rita Nano, Lorenzo Piemonti, Paul R.V. Johnson, Rebecca Spiers, Jennie Roberts, Gareth G. Lavery, Anne Clark, Carlo D.L. Ceresa, David W. Ray, Leanne Hodson, Amy P. Davies, Guy A. Rutter, Masaya Oshima, Raphaël Scharfmann, Matthew J. Merrins, Ildem Akerman, Daniel A. Tennant, Christian Ludwig, David J. Hodson

Get full text

NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency by Congxin Sun, Elena Seranova, Malkiel A. Cohen, Miruna Chipara, Jennie Roberts, Dewi Astuti, Adina M. Palhegyi, Animesh Acharjee, Lucia Sedlackova, Tetsushi Kataura, Elsje G. Otten, Prashanta K. Panda, Samuel Lara-Reyna, Miriam E. Korsgen, Kevin J. Kauffman, Alejandro Huerta-Uribe, Malgorzata Zatyka, Luiz F.S.E. Silva, Jorge Torresi, Shupei Zhang, Georgina W. Hughes, Carl Ward, Erich R. Kuechler, David Cartwright, Sergey Trushin, Eugenia Trushina, Gaurav Sahay, Yosef Buganim, Gareth G. Lavery, Joerg Gsponer, Daniel G. Anderson, Eva-Maria Frickel, Tatiana R. Rosenstock, Timothy Barrett, Oliver D.K. Maddocks, Daniel A. Tennant, Haoyi Wang, Rudolf Jaenisch, Viktor I. Korolchuk, Sovan Sarkar

Get full text