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An immunomodulating peptide with potential to suppress tumour growth and autoimmunity by Michael Agrez, Christopher Chandler, Kristofer J. Thurecht, Nicholas L. Fletcher, Feifei Liu, Gayathri Subramaniam, Christopher B. Howard, Benjamin Blyth, Stephen Parker, Darryl Turner, Justyna Rzepecka, Gavin Knox, Anastasia Nika, Andrew M. Hall, Hayley Gooding, Laura Gallagher
Published 2023-11-01
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497 PTT-4256 is a first-in-class small molecule inhibitor of GPR65 that counteracts the low pH-dependent immunosuppressive effects on immune cells and displays pronounced anti-tumo... by David Miller, Alastair Corbin, Barbara Young, Preeti Singh, Tobias Bopp, Darryl Turner, Barbara Cipriani, Alan Naylor, Gavin Milne, Rupert Satchell, Mussa Quareshy, Sourav Sarkar, Tobias Moechel, Philip MacFaul, Stuart Paine, Oliver Horne, Jessica Holien, Anastasia Nika, Gavin Knox, Toszka Bohn, Tom McCarthy, Stuart Hughes
Published 2023-11-01Article -
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An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage by Michael Agrez, Mark Stephen Rybchyn, Warusavithana Gunawardena Manori De Silva, Rebecca Sara Mason, Christopher Chandler, Terrence J. Piva, Kristofer Thurecht, Nicholas Fletcher, Feifei Liu, Gayathri Subramaniam, Christopher B. Howard, Benjamin Blyth, Stephen Parker, Darryl Turner, Justyna Rzepecka, Gavin Knox, Anastasia Nika, Andrew Hall, Hayley Gooding, Laura Gallagher
Published 2023-07-01
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