An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention 由 Jørsboe, E, Andersen, MK, Skotte, L, Stæger, FF, Færgeman, NJ, Hanghøj, K, Santander, CG, Senftleber, NK, Diaz, LJ, Overvad, M, Waples, RK, Geller, F, Bjerregaard, P, Melbye, M, Larsen, CVL, Feenstra, B, Anders Koch, Jørgensen, ME, Grarup, N, Moltke, I, Albrechtsen, A, Hansen, T

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. 由 Rafnar, T, Sulem, P, Stacey, SN, Geller, F, Gudmundsson, J, Sigurdsson, A, Jakobsdottir, M, Helgadottir, H, Thorlacius, S, Aben, K, Blöndal, T, Thorgeirsson, T, Thorleifsson, G, Kristjansson, K, Thorisdottir, K, Ragnarsson, R, Sigurgeirsson, B, Skuladottir, H, Gudbjartsson, T, Isaksson, H, Einarsson, G, Benediktsdottir, K, Agnarsson, B, Olafsson, K, Salvarsdottir, A

Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. 由 Kiemeney, L, Thorlacius, S, Sulem, P, Geller, F, Aben, K, Stacey, SN, Gudmundsson, J, Jakobsdottir, M, Bergthorsson, J, Sigurdsson, A, Blondal, T, Witjes, J, Vermeulen, S, Hulsbergen-van de Kaa, C, Swinkels, D, Ploeg, M, Cornel, E, Vergunst, H, Thorgeirsson, T, Gudbjartsson, D, Gudjonsson, SA, Thorleifsson, G, Kristinsson, K, Mouy, M, Snorradottir, S

Sequence variant on 8q24 confers susceptibility to urinary bladder cancer 由 Kiemeney, L, Thorlacius, S, Sulem, P, Geller, F, Aben, K, Stacey, SN, Gudmundsson, J, Jakobsdottir, M, Bergthorsson, J, Sigurdsson, A, Blondal, T, Witjes, J, Vermeulen, S, Hulsbergen-van de Kaa, C, Swinkels, D, Ploeg, M, Cornel, E, Vergunst, H, Thorgeirsson, T, Gudbjartsson, D, Gudjonsson, SA, Thorleifsson, G, Kristinsson, K, Mouy, M, Snorradottir, S

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. 由 Hartz, S, Short, SE, Saccone, N, Culverhouse, R, Chen, L, Schwantes-An, T, Coon, H, Han, Y, Stephens, S, Sun, J, Chen, X, Ducci, F, Dueker, N, Franceschini, N, Frank, J, Geller, F, Gubjartsson, D, Hansel, N, Jiang, C, Keskitalo-Vuokko, K, Liu, Z, Lyytikäinen, L, Michel, M, Rawal, R, Rosenberger, A

Genome-wide association meta-analysis identifies five loci associated with postpartum hemorrhage 由 Westergaard, D, Steinthorsdottir, V, Stefansdottir, L, Rohde, PD, Wu, X, Geller, F, Tyrmi, J, Havulinna, AS, Solé-Navais, P, Flatley, C, Ostrowski, SR, Pedersen, OB, Erikstrup, C, Sørensen, E, Mikkelsen, C, Bruun, MT, Aagaard Jensen, B, Brodersen, T, Ullum, H, Magnus, P, Andreassen, OA, Njolstad, PR, Kolte, AM, Krebs, L, Lindgren, CM

A novel common variant in DCST2 is associated with length in early life and height in adulthood. 由 van der Valk, R, Kreiner-Møller, E, Kooijman, M, Guxens, M, Stergiakouli, E, Sääf, A, Bradfield, J, Geller, F, Hayes, MG, Cousminer, D, Körner, A, Thiering, E, Curtin, J, Myhre, R, Huikari, V, Joro, R, Kerkhof, M, Warrington, N, Pitkänen, N, Ntalla, I, Horikoshi, M, Veijola, R, Freathy, R, Teo, Y, Barton, S

Common variants at 12q15 and 12q24 are associated with infant head circumference 由 Rob Taal, H, St Pourcain, B, Thiering, E, Das, S, Mook-Kanamori, DO, Warrington, N, Kaakinen, M, Kreiner-Møller, E, Bradfield, J, Freathy, R, Geller, F, Guxens, M, Cousminer, D, Kerkhof, M, Timpson, N, Ikram, M, Beilin, L, Bønnelykke, K, Buxton, J, Charoen, P, Chawes, B, Eriksson, J, Evans, D, Hofman, A, Kemp, J

Genome-wide study identifies association between HLA-B∗55:01 and self-reported penicillin allergy 由 Krebs, K, Bovijn, J, Zheng, N, Lepamets, M, Censin, JC, Jürgenson, T, Särg, D, Abner, E, Laisk, T, Luo, Y, Skotte, L, Geller, F, Feenstra, B, Wang, W, Auton, A, 23andMe Research Team, Raychaudhuri, S, Esko, T, Metspalu, A, Laur, S, Roden, DM, Wei, W-Q, Holmes, MV, Lindgren, CM, Phillips, EJ, Mägi, R, Milani, L, Fadista, J

Common variants at 12q15 and 12q24 are associated with infant head circumference. 由 Taal, H, St Pourcain, B, Thiering, E, Das, S, Mook-Kanamori, DO, Warrington, N, Kaakinen, M, Kreiner-Møller, E, Bradfield, J, Freathy, R, Geller, F, Guxens, M, Cousminer, D, Kerkhof, M, Timpson, N, Ikram, M, Beilin, L, Bønnelykke, K, Buxton, J, Charoen, P, Chawes, B, Eriksson, J, Evans, D, Hofman, A, Kemp, J, Kim, C, Klopp, N, Lahti, J, Lye, S, McMahon, G, Mentch, F, Müller-Nurasyid, M, O'Reilly, P, Prokopenko, I, Rivadeneira, F, Steegers, E, Sunyer, J, Tiesler, C, Yaghootkar, H, Breteler, M, Decarli, C, Breteler, M, Debette, S, Fornage, M, Gudnason, V, Launer, L, van der Lugt, A, Mosley, T, Seshadri, S, Smith, A, Vernooij, M, Blakemore, A, Chiavacci, R, Feenstra, B, Fernandez-Banet, J, Grant, S, Hartikainen, A, van der Heijden, A, Iñiguez, C, Lathrop, M, McArdle, W, Mølgaard, A, Newnham, J, Palmer, L, Palotie, A, Pouta, A, Ring, S, Sovio, U, Standl, M, Uitterlinden, A, Wichmann, H, Vissing, N, DeCarli, C, van Duijn, C, McCarthy, M, Koppelman, G, Estivill, X, Hattersley, A, Melbye, M, Bisgaard, H, Pennell, C, Widen, E, Hakonarson, H, Smith, G, Heinrich, J, Jarvelin, MR, Jaddoe, V

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. 由 Beaumont, RN, Warrington, NM, Cavadino, A, Tyrrell, J, Nodzenski, M, Horikoshi, M, Geller, F, Myhre, R, Richmond, RC, Paternoster, L, Bradfield, JP, Kreiner-Møller, E, Huikari, V, Metrustry, S, Lunetta, KL, Painter, JN, Hottenga, J-J, Allard, C, Barton, SJ, Espinosa, A, Marsh, JA, Potter, C, Zhang, G, Ang, W, Berry, DJ, Bouchard, L, Das, S, Hakonarson, H, Heikkinen, J, Helgeland, Ø, Hocher, B, Hofman, A, Inskip, HM, Jones, SE, Kogevinas, M, Lind, PA, Marullo, L, Medland, SE, Murray, A, Murray, JC, Njølstad, PR, Nohr, EA, Reichetzeder, C, Ring, SM, Ruth, KS, Santa-Marina, L, Scholtens, DM, Sebert, S, Sengpiel, V, Tuke, MA, Vaudel, M, Weedon, MN, Willemsen, G, Wood, AR, Yaghootkar, H, Muglia, LJ, Bartels, M, Relton, CL, Pennell, CE, Chatzi, L, Estivill, X, Holloway, JW, Boomsma, DI, Montgomery, GW, Murabito, JM, Spector, TD, Power, C, Järvelin, M-R, Bisgaard, H, Grant, SF, Sørensen, TI, Jaddoe, VW, Jacobsson, B, Melbye, M, McCarthy, MI, Hattersley, AT, Hayes, MG, Frayling, TM, Hivert, M-F, Felix, JF, Hyppönen, E, Lowe, WL, Evans, DM, Lawlor, DA, Feenstra, B, Freathy, RM

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 由 Thorgeirsson, T, Gudbjartsson, D, Surakka, I, Vink, J, Amin, N, Geller, F, Sulem, P, Rafnar, T, Esko, T, Walter, S, Gieger, C, Rawal, R, Mangino, M, Prokopenko, I, Mägi, R, Keskitalo, K, Gudjonsdottir, I, Gretarsdottir, S, Stefansson, H, Thompson, JR, Aulchenko, Y, Nelis, M, Aben, K, den Heijer, M, Dirksen, A, Ashraf, H, Soranzo, N, Valdes, A, Steves, C, Uitterlinden, A, Hofman, A, Tönjes, A, Kovacs, P, Hottenga, J, Willemsen, G, Vogelzangs, N, Döring, A, Dahmen, N, Nitz, B, Pergadia, M, Saez, B, De Diego, V, Lezcano, V, Garcia-Prats, MD, Ripatti, S, Perola, M, Kettunen, J, Hartikainen, A, Pouta, A, Laitinen, J, Isohanni, M, Huei-Yi, S, Allen, M, Krestyaninova, M, Hall, A, Jones, G, van Rij, A, Mueller, T, Dieplinger, B, Haltmayer, M, Jonsson, S, Matthiasson, SE, Oskarsson, H, Tyrfingsson, T, Kiemeney, L, Mayordomo, J, Lindholt, J, Pedersen, J, Franklin, W, Wolf, H, Montgomery, G, Heath, A, Martin, N, Madden, P, Giegling, I, Rujescu, D, Järvelin, MR, Salomaa, V, Stumvoll, M, Spector, T, Wichmann, H, Metspalu, A, Samani, N, Penninx, B, Oostra, B, Boomsma, D, Tiemeier, H, van Duijn, C, Kaprio, J, Gulcher, JR, McCarthy, M, Peltonen, L, Thorsteinsdottir, U, Stefansson, K

Genome analyses of >200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders 由 Ligthart, S, Vaez, A, Võsa, U, Stathopoulou, MG, De Vries, PS, Prins, BP, Van Der Most, PJ, Tanaka, T, Naderi, E, Rose, LM, Wu, Y, Karlsson, R, Barbalic, M, Lin, H, Pool, R, Zhu, G, Macé, A, Sidore, C, Trompet, S, Mangino, M, Sabater-Lleal, M, Kemp, JP, Abbasi, A, Kacprowski, T, Verweij, N, Smith, AV, Huang, T, Marzi, C, Feitosa, MF, Lohman, KK, Kleber, ME, Milaneschi, Y, Mueller, C, Huq, M, Vlachopoulou, E, Lyytikäinen, L-P, Oldmeadow, C, Deelen, J, Perola, M, Zhao, JH, Feenstra, B, Lifelines Cohort Study, Amini, M, Charge Inflammation Working Group, Lahti, J, Schraut, KE, Fornage, M, Suktitipat, B, Chen, W-M, Li, X, Nutile, T, Malerba, G, Luan, J, Bak, T, Schork, N, Del Greco M, F, Thiering, E, Mahajan, A, Marioni, RE, Mihailov, E, Eriksson, J, Ozel, AB, Zhang, W, Nethander, M, Cheng, Y-C, Aslibekyan, S, Ang, W, Gandin, I, Yengo, L, Portas, L, Kooperberg, C, Hofer, E, Rajan, KB, Schurmann, C, Hollander, W, Ahluwalia, TS, Zhao, J, Draisma, HHM, Ford, I, Timpson, N, Teumer, A, Huang, H, Wahl, S, Liu, Y, Huang, J, Uh, H-W, Geller, F, Joshi, PK, Yanek, LR, Trabetti, E, Lehne, B, Vozzi, D, Verbanck, M, Biino, G, Saba, Y, Meulenbelt, I, O'Connell, JR, Laakso, M, Giulianini, F, Magnusson, PKE, Ballantyne, CM, Hottenga, JJ, Montgomery, GW, Rivadineira, F, Rueedi, R, Steri, M, Herzig, K-H, Stott, DJ, Menni, C, Frånberg, M, St Pourcain, B, Felix, SB, Pers, TH, Bakker, SJL, Kraft, P, Peters, A, Vaidya, D, Delgado, G, Smit, JH, Großmann, V, Sinisalo, J, Seppälä, I, Williams, SR, Holliday, EG, Moed, M, Langenberg, C, Räikkönen, K, Ding, J, Campbell, H, Sale, MM, Chen, Y-DI, James, AL, Ruggiero, D, Soranzo, N, Hartman, CA, Smith, EN, Berenson, GS, Fuchsberger, C, Hernandez, D, Tiesler, CMT, Giedraitis, V, Liewald, D, Fischer, K, Mellström, D, Larsson, A, Wang, Y, Scott, WR, Lorentzon, M, Beilby, J, Ryan, KA, Pennell, CE, Vuckovic, D, Balkau, B, Concas, MP, Schmidt, R, De Leon, CF, Bottinger, EP, Kloppenburg, M, Paternoster, L, Boehnke, M, Musk, AW, Willemsen, G, Evans, DM, Madden, PAF, Kähönen, M, Kutalik, Z, Zoledziewska, M, Karhunen, V, Kritchevsky, SB, Sattar, N, Lachance, G, Clarke, R, Harris, TB, Raitakari, OT, Attia, JR, Van Heemst, D, Kajantie, E, Sorice, R, Gambaro, G, Scott, RA, Hicks, AA, Ferrucci, L, Standl, M, Lindgren, CM, Starr, JM, Karlsson, M, Lind, L, Li, JZ, Chambers, JC, Mori, TA, De Geus, EJCN, Heath, AC, Martin, NG, Auvinen, J, Buckley, BM, De Craen, AJM, Waldenberger, M, Strauch, K, Meitinger, T, Scott, RJ, McEvoy, M, Beekman, M, Bombieri, C, Ridker, PM, Mohlke, KL, Pedersen, NL, Morrison, AC, Boomsma, DI, Whitfield, JB, Strachan, DP, Hofman, A, Vollenweider, P, Cucca, F, Jarvelin, M-R, Jukema, JW, Spector, TD, Hamsten, A, Zeller, T, Uitterlinden, AG, Nauck, M, Gudnason, V, Qi, L, Grallert, H, Borecki, IB, Rotter, JI, März, W, Wild, PS, Lokki, M-L, Boyle, M, Salomaa, V, Melbye, M, Eriksson, JG, Wilson, JF, Penninx, BWJH, Becker, DM, Worrall, BB, Gibson, G, Krauss, RM, Ciullo, M, Zaza, G, Wareham, NJ, Oldehinkel, AJ, Palmer, LJ, Murray, SS, Pramstaller, PP, Bandinelli, S, Heinrich, J, Ingelsson, E, Deary, IJ, Mägi, R, Vandenput, L, Van Der Harst, P, Desch, KC, Kooner, JS, Ohlsson, C, Hayward, C, Lehtimäki, T, Shuldiner, AR, Arnett, DK, Beilin, LJ, Robino, A, Froguel, P, Pirastu, M, Jess, T, Koenig, W, Loos, RJF, Evans, DA, Schmidt, H, Smith, GD, Slagboom, PE, Eiriksdottir, G, Morris, AP, Psaty, BM, Tracy, RP, Nolte, IM, Boerwinkle, E, Visvikis-Siest, S, Reiner, AP, Gross, M, Bis, JC, Franke, L, Franco, OH, Benjamin, EJ, Chasman, DI, Dupuis, J, Snieder, H, Dehghan, A, Alizadeh, BZ

Correction: the influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study 由 Winkler, T, Justice, A, Graff, M, Barata, L, Feitosa, M, Chu, S, Czajkowski, J, Esko, T, Fall, T, Kilpeläinen, T, Lu, Y, Mägi, R, Mihailov, E, Pers, T, Rüeger, S, Teumer, A, Ehret, G, Ferreira, T, Heard-Costa, N, Karjalainen, J, Lagou, V, Mahajan, A, Neinast, M, Prokopenko, I, Simino, J, Teslovich, T, Jansen, R, Westra, H, White, C, Absher, D, Ahluwalia, T, Ahmad, S, Albrecht, E, Alves, A, Bragg-Gresham, J, de Craen, A, Bis, J, Bonnefond, A, Boucher, G, Cadby, G, Cheng, Y, Chiang, C, Delgado, G, Demirkan, A, Dueker, N, Eklund, N, Eiriksdottir, G, Eriksson, J, Feenstra, B, Fischer, K, Frau, F, Galesloot, T, Geller, F, Goel, A, Gorski, M, Grammer, T, Gustafsson, S, Haitjema, S, Hottenga, J, Huffman, J, Jackson, A, Jacobs, K, Johansson, Å, Kaakinen, M, Kleber, M, Lahti, J, Mateo Leach, I, Lehne, B, Liu, Y, Lo, K, Lorentzon, M, Luan, J, Madden, P, Mangino, M, McKnight, B, Medina-Gomez, C, Monda, K, Montasser, M, Müller, G, Müller-Nurasyid, M, Nolte, I, Panoutsopoulou, K, Pascoe, L, Paternoster, L, Rayner, N, Renström, F, Rizzi, F, Rose, L, Ryan, K, Salo, P, Sanna, S, Scharnagl, H, Shi, J, Smith, A, Southam, L, Stančáková, A, Steinthorsdottir, V, Strawbridge, R, Sung, Y, Tachmazidou, I, Tanaka, T, Thorleifsson, G, Trompet, S, Pervjakova, N, Tyrer, J, Vandenput, L, van der Laan, S, van der Velde, N, van Setten, J, van Vliet-Ostaptchouk, J, Verweij, N, Vlachopoulou, E, Waite, L, Wang, S, Wang, Z, Wild, S, Willenborg, C, Wilson, J, Wong, A, Yang, J, Yengo, L, Yerges-Armstrong, L, Yu, L, Zhang, W, Zhao, J, Andersson, E, Bakker, S, Baldassarre, D, Banasik, K, Barcella, M, Barlassina, C, Bellis, C, Benaglio, P, Blangero, J, Blüher, M, Bonnet, F, Bonnycastle, L, Boyd, H, Bruinenberg, M, Buchman, A, Campbell, H, Chen, Y, Chines, P, Claudi-Boehm, S, Cole, J, Collins, F, de Geus, E, de Groot, L, Dimitriou, M, Duan, J, Enroth, S, Eury, E, Farmaki, A, Forouhi, N, Friedrich, N, Gejman, P, Gigante, B, Glorioso, N, Go, A, Gottesman, O, Gräßler, J, Grallert, H, Grarup, N, Gu, Y, Broer, L, Ham, A, Hansen, T, Harris, T, Hartman, C, Hassinen, M, Hastie, N, Hattersley, A, Heath, A, Henders, A, Hernandez, D, Hillege, H, Holmen, O, Hovingh, K, Hui, J, Husemoen, L, Hutri-Kähönen, N, Hysi, P, Illig, T, De Jager, P, Jalilzadeh, S, Jørgensen, T, Jukema, J, Juonala, M, Kanoni, S, Karaleftheri, M, Khaw, K, Kinnunen, L, Kittner, S, Koenig, W, Kolcic, I, Kovacs, P, Krarup, N, Kratzer, W, Krüger, J, Kuh, D, Kumari, M, Kyriakou, T, Langenberg, C, Lannfelt, L, Lanzani, C, Lotay, V, Launer, L, Leander, K, Lindström, J, Linneberg, A, Liu, Y, Lobbens, S, Luben, R, Lyssenko, V, Männistö, S, Magnusson, P, McArdle, W, Menni, C, Merger, S, Milani, L, Montgomery, G, Morris, A, Narisu, N, Nelis, M, Ong, K, Palotie, A, Pérusse, L, Pichler, I, Pilia, M, Pouta, A, Rheinberger, M, Ribel-Madsen, R, Richards, M, Rice, K, Rice, T, Rivolta, C, Salomaa, V, Sanders, A, Sarzynski, M, Scholtens, S, Scott, R, Scott, W, Sebert, S, Sengupta, S, Sennblad, B, Seufferlein, T, Silveira, A, Slagboom, P, Smit, J, Sparsø, T, Stirrups, K, Stolk, R, Stringham, H, Swertz, M, Swift, A, Syvänen, A, Tan, S, Thorand, B, Tönjes, A, Tremblay, A, Tsafantakis, E, van der Most, P, Völker, U, Vohl, M, Vonk, J, Waldenberger, M, Walker, R, Wennauer, R, Widén, E, Willemsen, G, Wilsgaard, T, Wright, A, Zillikens, M, van Dijk, S, van Schoor, N, Asselbergs, F, de Bakker, P, Beckmann, J, Beilby, J, Bennett, D, Bergman, R, Bergmann, S, Böger, C, Boehm, B, Boerwinkle, E, Boomsma, D, Bornstein, S, Bottinger, E, Bouchard, C, Chambers, J, Chanock, S, Chasman, D, Cucca, F, Cusi, D, Dedoussis, G, Erdmann, J, Eriksson, J, Evans, D, de Faire, U, Farrall, M, Ferrucci, L, Ford, I, Franke, L, Franks, P, Froguel, P, Gansevoort, R, Gieger, C, Grönberg, H, Gudnason, V, Gyllensten, U, Hall, P, Hamsten, A, van der Harst, P, Hayward, C, Heliövaara, M, Hengstenberg, C, Hicks, A, Hingorani, A, Hofman, A, Hu, F, Huikuri, H, Hveem, K, James, A, Jordan, J, Jula, A, Kähönen, M, Kajantie, E, Kathiresan, S, Kiemeney, L, Kivimaki, M, Knekt, P, Koistinen, H, Kooner, J, Koskinen, S, Kuusisto, J, Maerz, W, Martin, N, Laakso, M, Lakka, T, Lehtimäki, T, Lettre, G, Levinson, D, Lind, L, Lokki, M, Mäntyselkä, P, Melbye, M, Metspalu, A, Mitchell, B, Moll, F, Murray, J, Musk, A, Nieminen, M, Njølstad, I, Ohlsson, C, Oldehinkel, A, Oostra, B, Palmer, L, Pankow, J, Pasterkamp, G, Pedersen, N, Pedersen, O, Penninx, B, Perola, M, Peters, A, Polašek, O, Pramstaller, P, Psaty, B, Qi, L, Quertermous, T, Raitakari, O, Rankinen, T, Rauramaa, R, Ridker, P, Rioux, J, Rivadeneira, F, Rotter, J, Rudan, I, den Ruijter, H, Saltevo, J, Sattar, N, Schunkert, H, Schwarz, P, Shuldiner, A, Sinisalo, J, Snieder, H, Sørensen, T, Spector, T, Staessen, J, Stefania, B, Thorsteinsdottir, U, Stumvoll, M, Tardif, J, Tremoli, E, Tuomilehto, J, Uitterlinden, A, Uusitupa, M, Verbeek, A, Vermeulen, S, Viikari, J, Vitart, V, Völzke, H, Vollenweider, P, Waeber, G, Walker, M, Wallaschofski, H, Wareham, N, Watkins, H, Zeggini, E, Chakravarti, A, Clegg, D, Cupples, L, Gordon-Larsen, P, Jaquish, C, Rao, D, Abecasis, G, Assimes, T, Barroso, I, Berndt, S, Boehnke, M, Deloukas, P, Fox, C, Groop, L, Hunter, D, Ingelsson, E, Kaplan, R, McCarthy, M, Mohlke, K, O'Connell, J, Schlessinger, D, Strachan, D, Stefansson, K, van Duijn, C, Hirschhorn, J, Lindgren, C, Heid, I, North, K, Borecki, I, Kutalik, Z, Loos, R