Short PDE4 Isoforms as Drug Targets in Disease by Elka Kyurkchieva, George S. Baillie

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Phosphodiesterase 4B: Master Regulator of Brain Signaling by Amy J. Tibbo, George S. Baillie

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PDE4-Mediated cAMP Signalling by Bracy A. Fertig, George S. Baillie

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Reduced PDE4D7 in prostate cancer correlates with genomic downregulation within the upstream PDE4D coding region by Chloe Gulliver, George S Baillie, Ralf Hoffmann

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Frontiers in the pharmacological manipulation of intracellular cAMP levels by George Scott Baillie, Frank eChristian, Apostolos eZarros

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The CAPRA&PDE4D5/7/9 Prognostic Model Is Significantly Associated with Adverse Post-Surgical Pathology Outcomes by Chloe Gulliver, Sebastian Huss, Axel Semjonow, George S. Baillie, Ralf Hoffmann

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cAMP‐phosphodiesterase 4D7 (PDE4D7) forms a cAMP signalosome complex with DHX9 and is implicated in prostate cancer progression by Chloe Gulliver, Tara Busiau, Ashleigh Byrne, Jane E. Findlay, Ralf Hoffmann, George S. Baillie

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Targeting B-Raf inhibitor resistant melanoma with novel cell penetrating peptide disrupters of PDE8A – C-Raf by Connor M. Blair, Nicola M. Walsh, Bruce H. Littman, Frank W. Marcoux, George S. Baillie

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Targeted disruption of the heat shock protein 20–phosphodiesterase 4D (PDE4D) interaction protects against pathological cardiac remodelling in a mouse model of hypertrophy by Tamara P. Martin, Maria P. Hortigon-Vinagre, Jane E. Findlay, Christina Elliott, Susan Currie, George S. Baillie

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PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex by Arman Javadi, Ravi K Deevi, Emma Evergren, Elodie Blondel-Tepaz, George S Baillie, Mark GH Scott, Frederick C Campbell

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Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks by Christina Schoenherr, Adam Byron, Emma Sandilands, Ketevan Paliashvili, George S Baillie, Amaya Garcia-Munoz, Cristina Valacca, Francesco Cecconi, Bryan Serrels, Margaret C Frame

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Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies by Alice Main, Andri Boguslavskyi, Jacqueline Howie, Chien-Wen Kuo, Aileen Rankin, Francis L. Burton, Godfrey L. Smith, Roger Hajjar, George S. Baillie, Kenneth S. Campbell, Michael J. Shattock, William Fuller

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Identification and Characterization of an Affimer Affinity Reagent for the Detection of the cAMP Sensor, EPAC1 by Hanna K. Buist, Urszula Luchowska-Stańska, Boy van Basten, Jessica Valli, Brian O. Smith, George S. Baillie, Colin Rickman, Bryon Ricketts, Alex Davidson, Ryan Hannam, Joanne Sunderland, Stephen J. Yarwood

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Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC by Sean F. Cooke, Thomas A. Wright, Yuan Yan Sin, Jiayue Ling, Elka Kyurkchieva, Nattaporn Phanthaphol, Thomas Mcskimming, Katharine Herbert, Selma Rebus, Andrew V. Biankin, David K. Chang, George S. Baillie, Connor M. Blair

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Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction. by Amit Mahindra, Gonzalo Tejeda, Mario Rossi, Omar Janha, Imogen Herbert, Caroline Morris, Danielle C Morgan, Wendy Beattie, Augusto C Montezano, Brian Hudson, Andrew B Tobin, David Bhella, Rhian M Touyz, Andrew G Jamieson, George S Baillie, Connor M Blair

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Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction by Amit Mahindra, Gonzalo Tejeda, Mario Rossi, Omar Janha, Imogen Herbert, Caroline Morris, Danielle C. Morgan, Wendy Beattie, Augusto C. Montezano, Brian Hudson, Andrew B. Tobin, David Bhella, Rhian M. Touyz, Andrew G. Jamieson, George S. Baillie, Connor M. Blair

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Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1 by Robbert Havekes, Alan J Park, Jennifer C Tudor, Vincent G Luczak, Rolf T Hansen, Sarah L Ferri, Vibeke M Bruinenberg, Shane G Poplawski, Jonathan P Day, Sara J Aton, Kasia Radwańska, Peter Meerlo, Miles D Houslay, George S Baillie, Ted Abel

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Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif by Alain Ibáñez de Opakua, Kshitij Parag-Sharma, Vincent DiGiacomo, Nekane Merino, Anthony Leyme, Arthur Marivin, Maider Villate, Lien T. Nguyen, Miguel Angel de la Cruz-Morcillo, Juan B. Blanco-Canosa, Sekar Ramachandran, George S. Baillie, Richard A. Cerione, Francisco J. Blanco, Mikel Garcia-Marcos

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p75 Neurotrophin Receptor Regulates Energy Balance in Obesity by Bernat Baeza-Raja, Benjamin D. Sachs, Pingping Li, Frank Christian, Eirini Vagena, Dimitrios Davalos, Natacha Le Moan, Jae Kyu Ryu, Shoana L. Sikorski, Justin P. Chan, Miriam Scadeng, Susan S. Taylor, Miles D. Houslay, George S. Baillie, Alan R. Saltiel, Jerrold M. Olefsky, Katerina Akassoglou

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