Short PDE4 Isoforms as Drug Targets in Disease av Elka Kyurkchieva, George S. Baillie

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Phosphodiesterase 4B: Master Regulator of Brain Signaling av Amy J. Tibbo, George S. Baillie

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PDE4-Mediated cAMP Signalling av Bracy A. Fertig, George S. Baillie

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Reduced PDE4D7 in prostate cancer correlates with genomic downregulation within the upstream PDE4D coding region av Chloe Gulliver, George S Baillie, Ralf Hoffmann

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The enigmatic helicase DHX9 and its association with the hallmarks of cancer av Chloe Gulliver, Ralf Hoffmann, George S Baillie

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cAMP‐phosphodiesterase 4D7 (PDE4D7) forms a cAMP signalosome complex with DHX9 and is implicated in prostate cancer progression av Chloe Gulliver, Tara Busiau, Ashleigh Byrne, Jane E. Findlay, Ralf Hoffmann, George S. Baillie

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Targeting B-Raf inhibitor resistant melanoma with novel cell penetrating peptide disrupters of PDE8A – C-Raf av Connor M. Blair, Nicola M. Walsh, Bruce H. Littman, Frank W. Marcoux, George S. Baillie

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Targeted disruption of the heat shock protein 20–phosphodiesterase 4D (PDE4D) interaction protects against pathological cardiac remodelling in a mouse model of hypertrophy av Tamara P. Martin, Maria P. Hortigon-Vinagre, Jane E. Findlay, Christina Elliott, Susan Currie, George S. Baillie

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PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex av Arman Javadi, Ravi K Deevi, Emma Evergren, Elodie Blondel-Tepaz, George S Baillie, Mark GH Scott, Frederick C Campbell

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Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability av Jamie J. L. Williams, Nasser Alotaiq, William Mullen, Richard Burchmore, Libin Liu, George S. Baillie, Fred Schaper, Paul F. Pilch, Timothy M. Palmer

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Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks av Christina Schoenherr, Adam Byron, Emma Sandilands, Ketevan Paliashvili, George S Baillie, Amaya Garcia-Munoz, Cristina Valacca, Francesco Cecconi, Bryan Serrels, Margaret C Frame

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The Association of the Long Prostate Cancer Expressed PDE4D Transcripts to Poor Patient Outcome Depends on the Tumour’s TMPRSS2-ERG Fusion Status av Dianne van Strijp, Christiane de Witz, Birthe Heitkötter, Sebastian Huss, Martin Bögemann, George S. Baillie, Miles D. Houslay, Chris Bangma, Axel Semjonow, Ralf Hoffmann

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Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies av Alice Main, Andri Boguslavskyi, Jacqueline Howie, Chien-Wen Kuo, Aileen Rankin, Francis L. Burton, Godfrey L. Smith, Roger Hajjar, George S. Baillie, Kenneth S. Campbell, Michael J. Shattock, William Fuller

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Identification and Characterization of an Affimer Affinity Reagent for the Detection of the cAMP Sensor, EPAC1 av Hanna K. Buist, Urszula Luchowska-Stańska, Boy van Basten, Jessica Valli, Brian O. Smith, George S. Baillie, Colin Rickman, Bryon Ricketts, Alex Davidson, Ryan Hannam, Joanne Sunderland, Stephen J. Yarwood

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Clinacanthus nutans extract lowers periodontal inflammation under high-glucose conditions via inhibiting NF-κB signaling pathway av Saruda Thongyim, Saruda Thongyim, Saruda Thongyim, Thomas A. Wright, Pachara Sattayawat, Pachara Sattayawat, Thida Kaewkod, Thida Kaewkod, George S. Baillie, Yingmanee Tragoolpua, Yingmanee Tragoolpua, Siriphorn Jangsutthivorawat, Aussara Panya, Aussara Panya, Aussara Panya

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Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC av Sean F. Cooke, Thomas A. Wright, Yuan Yan Sin, Jiayue Ling, Elka Kyurkchieva, Nattaporn Phanthaphol, Thomas Mcskimming, Katharine Herbert, Selma Rebus, Andrew V. Biankin, David K. Chang, George S. Baillie, Connor M. Blair

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Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction av Amit Mahindra, Gonzalo Tejeda, Mario Rossi, Omar Janha, Imogen Herbert, Caroline Morris, Danielle C. Morgan, Wendy Beattie, Augusto C. Montezano, Brian Hudson, Andrew B. Tobin, David Bhella, Rhian M. Touyz, Andrew G. Jamieson, George S. Baillie, Connor M. Blair

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Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1 av Robbert Havekes, Alan J Park, Jennifer C Tudor, Vincent G Luczak, Rolf T Hansen, Sarah L Ferri, Vibeke M Bruinenberg, Shane G Poplawski, Jonathan P Day, Sara J Aton, Kasia Radwańska, Peter Meerlo, Miles D Houslay, George S Baillie, Ted Abel

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Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif av Alain Ibáñez de Opakua, Kshitij Parag-Sharma, Vincent DiGiacomo, Nekane Merino, Anthony Leyme, Arthur Marivin, Maider Villate, Lien T. Nguyen, Miguel Angel de la Cruz-Morcillo, Juan B. Blanco-Canosa, Sekar Ramachandran, George S. Baillie, Richard A. Cerione, Francisco J. Blanco, Mikel Garcia-Marcos

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p75 Neurotrophin Receptor Regulates Energy Balance in Obesity av Bernat Baeza-Raja, Benjamin D. Sachs, Pingping Li, Frank Christian, Eirini Vagena, Dimitrios Davalos, Natacha Le Moan, Jae Kyu Ryu, Shoana L. Sikorski, Justin P. Chan, Miriam Scadeng, Susan S. Taylor, Miles D. Houslay, George S. Baillie, Alan R. Saltiel, Jerrold M. Olefsky, Katerina Akassoglou

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