Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity by Yihe Wang, Astrid Hammer, Gerald Hoefler, Ernst Malle, Clare L. Hawkins, Christine Y. Chuang, Michael J. Davies

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Tumor-Induced Hyperlipidemia Contributes to Tumor Growth by Jianfeng Huang, Lena Li, Jihong Lian, Silvia Schauer, Paul W. Vesely, Dagmar Kratky, Gerald Hoefler, Richard Lehner

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Cannabinoids Reduce Melanoma Cell Viability and Do Not Interfere with Commonly Used Targeted Therapy in Metastatic Melanoma In Vivo and In Vitro by Georg Richtig, Melanie Kienzl, Sonja Rittchen, David Roula, Jürgen Eberle, Zina Sarif, Martin Pichler, Gerald Hoefler, Akos Heinemann

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The inflammatory oxidant peroxynitrous acid modulates the structure and function of the recombinant human V3 isoform of the extracellular matrix proteoglycan versican by Sara M. Jørgensen, Lasse G. Lorentzen, Astrid Hammer, Gerald Hoefler, Ernst Malle, Christine Y. Chuang, Michael J. Davies

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Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats by Juste Maneikyte, Augustinas Bausys, Bettina Leber, Nicole Feldbacher, Gerald Hoefler, Dagmar Kolb-Lenz, Kestutis Strupas, Philipp Stiegler, Peter Schemmer

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Cancer induces cardiomyocyte remodeling and hypoinnervation in the left ventricle of the mouse heart. by Christian Mühlfeld, Suman Kumar Das, Frank R Heinzel, Albrecht Schmidt, Heiner Post, Silvia Schauer, Tamara Papadakis, Wolfgang Kummer, Gerald Hoefler

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Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis by H. Furkan Alkan, Paul W. Vesely, Hubert Hackl, Johannes Foßelteder, Daniel R. Schmidt, Matthew G. Vander Heiden, Martin Pichler, Gerald Hoefler, Juliane G. Bogner-Strauss

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Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling by Sascha Obrowsky, Prakash G. Chandak, Jay V. Patankar, Silvia Povoden, Stefanie Schlager, Erin E. Kershaw, Juliane G. Bogner-Strauss, Gerald Hoefler, Sanja Levak-Frank, Dagmar Kratky

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Hypochlorite-Modified LDL Induces Arrhythmia and Contractile Dysfunction in Cardiomyocytes by Chintan N. Koyani, Susanne Scheruebel, Ge Jin, Ewald Kolesnik, Klaus Zorn-Pauly, Heinrich Mächler, Gerald Hoefler, Dirk von Lewinski, Frank R. Heinzel, Brigitte Pelzmann, Ernst Malle

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Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing. by Sumitra Mohan, Ellen Heitzer, Peter Ulz, Ingrid Lafer, Sigurd Lax, Martina Auer, Martin Pichler, Armin Gerger, Florian Eisner, Gerald Hoefler, Thomas Bauernhofer, Jochen B Geigl, Michael R Speicher

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Microbiota-derived genotoxin tilimycin generates colonic stem cell mutations by Lisa Pöltl, Maksym Kitsera, Sandra Raffl, Stefan Schild, Amar Cosic, Sabine Kienesberger, Katrin Unterhauser, Georg Raber, Christian Lembacher-Fadum, Rolf Breinbauer, Gregor Gorkiewicz, Carlos Sebastian, Gerald Hoefler, Ellen L. Zechner

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External validation of the derived neutrophil to lymphocyte ratio as a prognostic marker on a large cohort of pancreatic cancer patients. by Joanna Szkandera, Michael Stotz, Florian Eisner, Gudrun Absenger, Tatjana Stojakovic, Hellmut Samonigg, Peter Kornprat, Renate Schaberl-Moser, Wael Alzoughbi, Anna Lena Ress, Friederike Sophia Seggewies, Armin Gerger, Gerald Hoefler, Martin Pichler

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Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer by Peter Ulz, Jelena Belic, Ricarda Graf, Martina Auer, Ingrid Lafer, Katja Fischereder, Gerald Webersinke, Karl Pummer, Herbert Augustin, Martin Pichler, Gerald Hoefler, Thomas Bauernhofer, Jochen B. Geigl, Ellen Heitzer, Michael R. Speicher

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R‐ketorolac ameliorates cancer‐associated cachexia and prolongs survival of tumour‐bearing mice by Sophia E. Chrysostomou, Sandra Eder, Isabella Pototschnig, Anna‐Lena Mayer, Martina Derler, Marion Mussbacher, Silvia Schauer, Dongxu Zhang, Dongmei Yan, Gennie Liu, Gerald Hoefler, Thomas Weichhart, Paul W. Vesely, Lingbing Zhang, Martina Schweiger

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Impact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration by Valentina Bianco, Melanie Korbelius, Nemanja Vujic, Alena Akhmetshina, Melina Amor, Dagmar Kolb, Anita Pirchheim, Ivan Bradic, Katharina B. Kuentzel, Martin Buerger, Silvia Schauer, Huyen T.T. Phan, Dominik Bulfon, Gerald Hoefler, Robert Zimmermann, Dagmar Kratky

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SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types. by Georg Richtig, Ariane Aigelsreiter, Daniela Schwarzenbacher, Anna Lena Ress, Jan Basri Adiprasito, Verena Stiegelbauer, Gerald Hoefler, Silvia Schauer, Tobias Kiesslich, Peter Kornprat, Thomas Winder, Florian Eisner, Armin Gerger, Herbert Stoeger, Rudolf Stauber, Carolin Lackner, Martin Pichler

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Profiling of circulating tumor DNA and tumor tissue for treatment selection in patients with advanced and refractory carcinoma: a prospective, two-stage phase II Individualized Can... by Jakob M. Riedl, Samantha O. Hasenleithner, Gudrun Pregartner, Lukas Scheipner, Florian Posch, Karin Groller, Karl Kashofer, Stephan W. Jahn, Thomas Bauernhofer, Martin Pichler, Herbert Stöger, Andrea Berghold, Gerald Hoefler, Michael R. Speicher, Ellen Heitzer, Armin Gerger

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Adipose triglyceride lipase–mediated lipid catabolism is essential for bronchiolar regeneration by Manu Manjunath Kanti, Isabelle Striessnig-Bina, Beatrix Irene Wieser, Silvia Schauer, Gerd Leitinger, Thomas O. Eichmann, Martina Schweiger, Margit Winkler, Elke Winter, Andrea Lana, Iris Kufferath, Leigh Matthew Marsh, Grazyna Kwapiszewska, Rudolf Zechner, Gerald Hoefler, Paul Willibald Vesely

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Interleukin‐6 initiates muscle‐ and adipose tissue wasting in a novel C57BL/6 model of cancer‐associated cachexia by Isabella Pototschnig, Ursula Feiler, Clemens Diwoky, Paul W. Vesely, Thomas Rauchenwald, Margret Paar, Latifa Bakiri, Laura Pajed, Peter Hofer, Karl Kashofer, Nyamdelger Sukhbaatar, Gabriele Schoiswohl, Thomas Weichhart, Gerald Hoefler, Christoph Bock, Martin Pichler, Erwin F. Wagner, Rudolf Zechner, Martina Schweiger

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MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors by Daniela Schwarzenbacher, Christiane Klec, Barbara Pasculli, Stefanie Cerk, Beate Rinner, Michael Karbiener, Cristina Ivan, Raffaela Barbano, Hui Ling, Annika Wulf-Goldenberg, Stefanie Stanzer, Gabriel Rinnerthaler, Herbert Stoeger, Thomas Bauernhofer, Johannes Haybaeck, Gerald Hoefler, Stephan Wenzel Jahn, Paola Parrella, George Adrian Calin, Martin Pichler

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