Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2″)-Ia by Georgina Cox, Peter J. Stogios, Alexei Savchenko, Gerard D. Wright

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Three-Dimensional Structure and Optimization of the Metallo-β-Lactamase Inhibitor Aspergillomarasmine A by Kalinka Koteva, David Sychantha, Caitlyn M. Rotondo, Christian Hobson, James F. Britten, Gerard D. Wright

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GPAHex-A synthetic biology platform for Type IV–V glycopeptide antibiotic production and discovery by Min Xu, Wenliang Wang, Nicholas Waglechner, Elizabeth J. Culp, Allison K. Guitor, Gerard D. Wright

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Angucyclinones rescue PhLOPSA antibiotic activity by inhibiting Cfr-dependent antibiotic resistance by Adam J. Schaenzer, Annia Rodriguez Hernandez, Kaitlyn Tsai, Christian Hobson, Danica Galonić Fujimori, Gerard D. Wright

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A diverse intrinsic antibiotic resistome from a cave bacterium by Andrew C. Pawlowski, Wenliang Wang, Kalinka Koteva, Hazel A. Barton, Andrew G. McArthur, Gerard D. Wright

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The evolution of substrate discrimination in macrolide antibiotic resistance enzymes by Andrew C. Pawlowski, Peter J. Stogios, Kalinka Koteva, Tatiana Skarina, Elena Evdokimova, Alexei Savchenko, Gerard D. Wright

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Staphylococcus aureus susceptibility to complestatin and corbomycin depends on the VraSR two-component system by Carmen Gómez-Arrebola, Sara B. Hernandez, Elizabeth J. Culp, Gerard D. Wright, Cristina Solano, Felipe Cava, Iñigo Lasa

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An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens by Nicole Robbins, Michaela Spitzer, Tennison Yu, Robert P. Cerone, Anna K. Averette, Yong-Sun Bahn, Joseph Heitman, Donald C. Sheppard, Mike Tyers, Gerard D. Wright

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Capturing the antibiotic resistome of preterm infants reveals new benefits of probiotic supplementation by Allison K. Guitor, Efrah I. Yousuf, Amogelang R. Raphenya, Eileen K. Hutton, Katherine M. Morrison, Andrew G. McArthur, Gerard D. Wright, Jennifer C. Stearns

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Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family by Peter J. Stogios, Emily Bordeleau, Zhiyu Xu, Tatiana Skarina, Elena Evdokimova, Sommer Chou, Luke Diorio-Toth, Alaric W. D’Souza, Sanket Patel, Gautam Dantas, Gerard D. Wright, Alexei Savchenko

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Influence of Humans on Evolution and Mobilization of Environmental Antibiotic Resistome by William H. Gaze, Stephen M. Krone, D.G. Joakim Larsson, Xian-Zhi Li, Joseph A. Robinson, Pascal Simonet, Kornelia Smalla, Mohammed Timinouni, Ed Topp, Elizabeth M. Wellington, Gerard D. Wright, Yong-Guan Zhu

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Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture by Matthew C. Fisher, Sarah J. Gurr, Christina A. Cuomo, David S. Blehert, Hailing Jin, Eva H. Stukenbrock, Jason E. Stajich, Regine Kahmann, Charles Boone, David W. Denning, Neil A. R. Gow, Bruce S. Klein, James W. Kronstad, Donald C. Sheppard, John W. Taylor, Gerard D. Wright, Joseph Heitman, Arturo Casadevall, Leah E. Cowen

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Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation by Nicole M. Revie, Kali R. Iyer, Michelle E. Maxson, Jiabao Zhang, Su Yan, Caroline M. Fernandes, Kirsten J. Meyer, Xuefei Chen, Iwona Skulska, Meea Fogal, Hiram Sanchez, Saif Hossain, Sheena Li, Yoko Yashiroda, Hiroyuki Hirano, Minoru Yoshida, Hiroyuki Osada, Charles Boone, Rebecca S. Shapiro, David R. Andes, Gerard D. Wright, Justin R. Nodwell, Maurizio Del Poeta, Martin D. Burke, Luke Whitesell, Nicole Robbins, Leah E. Cowen

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