A Precision Medicine Approach to Optimize Modulator Therapy for Rare CFTR Folding Mutants by Guido Veit, Tony Velkov, Haijin Xu, Nathalie Vadeboncoeur, Lara Bilodeau, Elias Matouk, Gergely L. Lukacs

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Control of membrane protein homeostasis by a chaperone-like glial cell adhesion molecule at multiple subcellular locations by Haijin Xu, Sandra Isenmann, Tania López-Hernández, Raúl Estévez, Gergely L. Lukacs, Pirjo M. Apaja

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Nanomechanics combined with HDX reveals allosteric drug binding sites of CFTR NBD1 by Rita Padányi, Bianka Farkas, Hedvig Tordai, Bálint Kiss, Helmut Grubmüller, Naoto Soya, Gergely L. Lukács, Miklós Kellermayer, Tamás Hegedűs

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Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration by Dmitri Kharitidi, Pirjo M. Apaja, Sanaz Manteghi, Kei Suzuki, Elena Malitskaya, Ariel Roldan, Marie-Claude Gingras, Junichi Takagi, Gergely L. Lukacs, Arnim Pause

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Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination by Guido Veit, Ariel Roldan, Mark A. Hancock, Dillon F. Da Fonte, Haijin Xu, Maytham Hussein, Saul Frenkiel, Elias Matouk, Tony Velkov, Gergely L. Lukacs

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Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain–domain coupling by Naoto Soya, Haijin Xu, Ariel Roldan, Zhengrong Yang, Haoxin Ye, Fan Jiang, Aiswarya Premchandar, Guido Veit, Susan P. C. Cole, John Kappes, Tamás Hegedüs, Gergely L. Lukacs

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Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect. by Guido Veit, Kathryn Oliver, Pirjo M Apaja, Doranda Perdomo, Aurélien Bidaud-Meynard, Sheng-Ting Lin, Jingyu Guo, Mert Icyuz, Eric J Sorscher, John L Hartman, Gergely L Lukacs

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Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes by Jalal M. Kazan, Guillaume Desrochers, Claire E. Martin, Hyeonju Jeong, Dmitri Kharitidi, Pirjo M. Apaja, Ariel Roldan, Nicole St. Denis, Anne-Claude Gingras, Gergely L. Lukacs, Arnim Pause

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Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell by Miklos Bagdany, Guido Veit, Ryosuke Fukuda, Radu G. Avramescu, Tsukasa Okiyoneda, Imad Baaklini, Jay Singh, Guy Sovak, Haijin Xu, Pirjo M. Apaja, Sara Sattin, Lenore K. Beitel, Ariel Roldan, Giorgio Colombo, William Balch, Jason C. Young, Gergely L. Lukacs

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