A Proof-of-Concept Fragment Screening of a Hit-Validated 96-Compounds Library against Human Carbonic Anhydrase II by Steffen Glöckner, Andreas Heine, Gerhard Klebe

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Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage by Janis Müller, Romina A. Kirschner, Armin Geyer, Gerhard Klebe

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The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II by Steffen Glöckner, Khang Ngo, Björn Wagner, Andreas Heine, Gerhard Klebe

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Crystallographic Fragment Screening on the Shigella Type III Secretion System Chaperone IpgC by Marina Gárdonyi, Christian Hasewinkel, Johanna Wallbaum, Jan Wollenhaupt, Manfred S. Weiss, Gerhard Klebe, Klaus Reuter, Andreas Heine

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Which Properties Allow Ligands to Open and Bind to the Transient Binding Pocket of Human Aldose Reductase? by Anna Sandner, Khang Ngo, Christoph P. Sager, Frithjof Scheer, Michael Daude, Wibke E. Diederich, Andreas Heine, Gerhard Klebe

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Investigation of specificity determinants in bacterial tRNA-guanine transglycosylase reveals queuine, the substrate of its eucaryotic counterpart, as inhibitor. by Inna Biela, Naomi Tidten-Luksch, Florian Immekus, Serghei Glinca, Tran Xuan Phong Nguyen, Hans-Dieter Gerber, Andreas Heine, Gerhard Klebe, Klaus Reuter

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Soaking suggests "alternative facts": Only co-crystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-... by Frederik Rainer Ehrmann, Johann Stojko, Alexander Metz, François Debaene, Luzi Jakob Barandun, Andreas Heine, François Diederich, Sarah Cianférani, Klaus Reuter, Gerhard Klebe

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