Understanding the Mechanism of Action of Melatonin, Which Induces ROS Production in Cancer Cells by Javier Florido, César Rodriguez-Santana, Laura Martinez-Ruiz, Alba López-Rodríguez, Darío Acuña-Castroviejo, Iryna Rusanova, Germaine Escames

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A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the i... by Miguel Rodríguez-Rubio, Juan Carlos Figueira, Darío Acuña-Castroviejo, Alberto M. Borobia, Germaine Escames, Pedro de la Oliva

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A bioengineered tumor matrix-based scaffold for the evaluation of melatonin efficacy on head and neck squamous cancer stem cells by Julia López de Andrés, César Rodríguez-Santana, Laura de Lara-Peña, Gema Jiménez, Germaine Escames, Juan Antonio Marchal

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ZEBRAFISH PARKINSONISM AFFECTS CLOCK GENES EXPRESSION, CAUSING CHRONODISRUPTION-RELATED LOSS OF LOCOMOTOR ACTIVITY, MELATONIN RHYTHM, AND MITOCHONDRIAL DYNAMICS SHIFT, WHICH ARE RE... by Paula Aranda Martinez, Jose Fernández Martínez, Yolanda Ramírez Casas, Ana Guerra-Librero, Germaine Escames Rosa, Darío Acuña Castroviejo

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Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial diseaseResearch in context by Eliana Barriocanal-Casado, Agustín Hidalgo-Gutiérrez, Nuno Raimundo, Pilar González-García, Darío Acuña-Castroviejo, Germaine Escames, Luis C. López

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Chronodisruption and Loss of Melatonin Rhythm, Associated with Alterations in Daily Motor Activity and Mitochondrial Dynamics in Parkinsonian Zebrafish, Are Corrected by Melatonin... by Paula Aranda-Martínez, José Fernández-Martínez, Yolanda Ramírez-Casas, César Rodríguez-Santana, Iryna Rusanova, Germaine Escames, Darío Acuña-Castroviejo

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From Chronodisruption to Sarcopenia: The Therapeutic Potential of Melatonin by José Fernández-Martínez, Yolanda Ramírez-Casas, Yang Yang, Paula Aranda-Martínez, Laura Martínez-Ruiz, Germaine Escames, Darío Acuña-Castroviejo

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Changes in Cortisol and in Oxidative/Nitrosative Stress Indicators after ADHD Treatment by Laura Garre-Morata, Tomás de Haro, Raquel González Villén, María Luisa Fernández-López, Germaine Escames, Antonio Molina-Carballo, Darío Acuña-Castroviejo

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Identification of PIK3CG as a hub in septic myocardial injury using network pharmacology and weighted gene co‐expression network analysis by Qiong Liu, Yushu Dong, Germaine Escames, Xue Wu, Jun Ren, Wenwen Yang, Shaofei Zhang, Yanli Zhu, Ye Tian, Darío Acuña‐Castroviejo, Yang Yang

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Melatonin/Nrf2/NLRP3 Connection in Mouse Heart Mitochondria during Aging by Marisol Fernández-Ortiz, Ramy K. A. Sayed, José Fernández-Martínez, Antonia Cionfrini, Paula Aranda-Martínez, Germaine Escames, Tomás de Haro, Darío Acuña-Castroviejo

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The NLRP3 inflammasome: contributions to inflammation-related diseases by Ying Chen, Xingyan Ye, Germaine Escames, Wangrui Lei, Xin Zhang, Meng Li, Tong Jing, Yu Yao, Zhenye Qiu, Zheng Wang, Darío Acuña-Castroviejo, Yang Yang

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MELATONIN-PRIMED MESENCHYMAL STROMAL CELLS INTERFERE WITH TUMOR MICROENVIRONMENT DYNAMICS AND REDUCE GLIOBLASTOMA MALIGNANCY. by Laura Olmedo Moreno, Paula Juárez Blázquez, Norma Adán Castro, Concepción Panadero Morón, Germaine Escames Rosa, Alejandro Martín Montalvo, José Manuel García Verdugo, Vivian Capilla-González

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Effect of 5-Azacitidine Treatment on Redox Status and Inflammatory Condition in MDS Patients by Paola Montes, Ana Guerra-Librero, Paloma García, María Elena Cornejo-Calvo, María del Señor López, Tomás de Haro, Laura Martínez-Ruiz, Germaine Escames, Darío Acuña-Castroviejo

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Human papillomavirus-associated head and neck squamous cell carcinoma cells lose viability during triggered myocyte lineage differentiation by Sarah Gendreizig, Laura Martínez-Ruiz, Alba López-Rodríguez, Harkiren Pabla, Leonie Hose, Frank Brasch, Tobias Busche, Germaine Escames, Holger Sudhoff, Lars Uwe Scholtz, Ingo Todt, Felix Oppel

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Targeting NR1D1 in organ injury: challenges and prospects by Zi-Yin Zhang-sun, Xue-Zeng Xu, Germaine Escames, Wang-Rui Lei, Lin Zhao, Ya-Zhe Zhou, Ye Tian, Ya-Nan Ren, Darío Acuña-Castroviejo, Yang Yang

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The Impact of Melatonin Supplementation and NLRP3 Inflammasome Deletion on Age-Accompanied Cardiac Damage by Ramy K. A. Sayed, Marisol Fernández-Ortiz, Ibtissem Rahim, José Fernández-Martínez, Paula Aranda-Martínez, Iryna Rusanova, Laura Martínez-Ruiz, Reem M. Alsaadawy, Germaine Escames, Darío Acuña-Castroviejo

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Role of c-miR-21, c-miR-126, Redox Status, and Inflammatory Conditions as Potential Predictors of Vascular Damage in T2DM Patients by Gabriela C. López-Armas, Arailym Yessenbekova, Rocío E. González-Castañeda, Kevin J. Arellano-Arteaga, Ana Guerra-Librero, Nurzhanyat Ablaikhanova, Javier Florido, Germaine Escames, Darío Acuña-Castroviejo, Iryna Rusanova

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The Impact of Melatonin and NLRP3 Inflammasome on the Expression of microRNAs in Aged Muscle by Ramy KA Sayed, Marisol Fernández-Ortiz, José Fernández-Martínez, Paula Aranda Martínez, Ana Guerra-Librero, César Rodríguez-Santana, Tomás de Haro, Germaine Escames, Darío Acuña-Castroviejo, Iryna Rusanova

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The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene by Marta Luna‐Sánchez, Elena Díaz‐Casado, Emanuele Barca, Miguel Ángel Tejada, Ángeles Montilla‐García, Enrique Javier Cobos, Germaine Escames, Dario Acuña‐Castroviejo, Catarina M Quinzii, Luis Carlos López

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β‐RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9R239X mice by Agustín Hidalgo‐Gutiérrez, Eliana Barriocanal‐Casado, Mohammed Bakkali, M Elena Díaz‐Casado, Laura Sánchez‐Maldonado, Miguel Romero, Ramy K Sayed, Cornelia Prehn, Germaine Escames, Juan Duarte, Darío Acuña‐Castroviejo, Luis C López

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