The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits. Tekijä Min, J, Taylor, J, Richards, J, Watts, T, Pettersson, F, Broxholme, J, Ahmadi, K, Surdulescu, G, Lowy, E, Gieger, C, Newton-Cheh, C, Perola, M, Soranzo, N, Surakka, I, Lindgren, C, Ragoussis, I, Morris, A, Cardon, L, Spector, T, Zondervan, K

Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations. Tekijä Org, E, Eyheramendy, S, Juhanson, P, Gieger, C, Lichtner, P, Klopp, N, Veldre, G, Döring, A, Viigimaa, M, Sõber, S, Tomberg, K, Eckstein, G, Kelgo, P, Rebane, T, Shaw-Hawkins, S, Howard, P, Onipinla, A, Dobson, R, Newhouse, S, Brown, M, Dominiczak, A, Connell, J, Samani, N, Farrall, M, Caulfield, M

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci Tekijä Tragante, V, Tragante, V, Barnes, MR, Ganesh, S, Lanktree, M, Guo, W, Franceschini, N, Smith, E, Johnson, T, Holmes, M, Padmanabhan, S, Karczewski, K, Almoguera, B, Barnard, J, Baumert, J, Chang, Y, Elbers, C, Elbers, C, Farrall, M, Farrall, M, Fischer, M, Gaunt, T, Gho, J, Gieger, C, Goel, A

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Tekijä Tragante, V, Barnes, MR, Ganesh, S, Lanktree, M, Guo, W, Franceschini, N, Smith, E, Johnson, T, Holmes, M, Padmanabhan, S, Karczewski, K, Almoguera, B, Barnard, J, Baumert, J, Chang, Y, Elbers, C, Farrall, M, Fischer, M, Gaunt, T, Gho, J, Gieger, C, Goel, A, Gong, Y, Isaacs, A, Kleber, M

Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways (Diabetes (2010) 59, (3229-3239)) Tekijä Soranzo, N, Sanna, S, Wheeler, E, Gieger, C, Radke, D, Dupuis, J, Bouatia-Naji, N, Langenberg, C, Prokopenko, I, Stolerman, E, Sandhu, MS, Heeney, M, Devaney, J, Reilly, M, Ricketts, S, Stewart, A, Voight, B, Willenborg, C, Wright, B, Altshuler, D, Arking, D, Balkau, B, Barnes, D, Boerwinkle, E, Böhm, B

Genetic architecture of circulating lipid levels. Tekijä Demirkan, A, Amin, N, Isaacs, A, Jarvelin, MR, Whitfield, J, Wichmann, H, Kyvik, K, Rudan, I, Gieger, C, Hicks, A, Johansson, Å, Hottenga, J, Smith, J, Wild, S, Pedersen, N, Willemsen, G, Mangino, M, Hayward, C, Uitterlinden, A, Hofman, A, Witteman, J, Montgomery, G, Pietiläinen, K, Rantanen, T, Kaprio, J

Loci influencing blood pressure identified using a cardiovascular gene-centric array. Tekijä Ganesh, S, Tragante, V, Guo, W, Guo, Y, Lanktree, M, Smith, E, Johnson, T, Castillo, B, Barnard, J, Baumert, J, Chang, Y, Elbers, C, Farrall, M, Fischer, M, Franceschini, N, Gaunt, T, Gho, J, Gieger, C, Gong, Y, Isaacs, A, Kleber, M, Mateo Leach, I, McDonough, C, Meijs, M, Mellander, O

European lactase persistence genotype shows evidence of association with increase in body mass index. Tekijä Kettunen, J, Silander, K, Saarela, O, Amin, N, Müller, M, Timpson, N, Surakka, I, Ripatti, S, Laitinen, J, Hartikainen, A, Pouta, A, Lahermo, P, Anttila, V, Männistö, S, Jula, A, Virtamo, J, Salomaa, V, Lehtimäki, T, Raitakari, O, Gieger, C, Wichmann, E, Van Duijn, C, Smith, G, McCarthy, M, Järvelin, MR

Genetic architecture of circulating lipid levels Tekijä Demirkan, A, Amin, N, Isaacs, A, Jarvelin, M, Whitfield, J, Wichmann, H, Kyvik, K, Rudan, I, Gieger, C, Hicks, A, Johansson, A, Hottenga, J, Smith, J, Wild, S, Pedersen, N, Willemsen, G, Mangino, M, Hayward, C, Uitterlinden, A, Hofman, A, Witteman, J, Montgomery, G, Pietiläinen, K, Rantanen, T, Kaprio, J

Loci influencing blood pressure identified using a cardiovascular gene-centric array Tekijä Ganesh, S, Tragante, V, Guo, W, Guo, Y, Lanktree, M, Smith, E, Johnson, T, Castillo, B, Barnard, J, Baumert, J, Chang, Y, Elbers, C, Farrall, M, Fischer, M, Gaunt, N, H Gho, J, Gieger, C, Gong, Y, Isaacs, A, Kleber, M, Leach, I, McDonough, C, Meijs, M, Mellander, O, Molony, C

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma Tekijä Chambers, J, Zhang, W, Sehmi, J, Li, X, Wass, M, Van der Harst, P, Holm, H, Sanna, S, Kavousi, M, Baumeister, SE, Coin, L, Deng, G, Gieger, C, Heard-Costa, N, Hottenga, J, Kühnel, B, Kumar, V, Lagou, V, Liang, L, Luan, J, Vidal, P, Leach, I, O'Reilly, P, Peden, J, Rahmioglu, N

Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array. Tekijä Sober, S, Org, E, Kepp, K, Juhanson, P, Eyheramendy, S, Gieger, C, Lichtner, P, Klopp, N, Veldre, G, Viigimaa, M, Doring, A, Putku, M, Kelgo, P, Shaw-Hawkins, S, Howard, P, Onipinla, A, Dobson, R, Newhouse, S, Brown, M, Dominiczak, A, Connell, J, Samani, N, Farrall, M, Caulfield, M, Munroe, P, Illig, T, Wichmann, H, Meitinger, T, Laan, M

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Tekijä Chambers, J, Zhang, W, Sehmi, J, Li, X, Wass, M, Van der Harst, P, Holm, H, Sanna, S, Kavousi, M, Baumeister, SE, Coin, L, Deng, G, Gieger, C, Heard-Costa, N, Hottenga, J, Kühnel, B, Kumar, V, Lagou, V, Liang, L, Luan, J, Vidal, P, Mateo Leach, I, O'Reilly, P, Peden, J, Rahmioglu, N

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study. Tekijä Molnos, S, Wahl, S, Haid, M, Eekhoff, E, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H, van Leeuwen, N, Simonis-Bik, A, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M, van Heemst, D, Pedersen, H, Gudmundsdottir, V, Schulze, M, Pischon, T, de Geus, E, Boeing, H, Boomsma, D, Ziegler, A, Slagboom, P, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M, Gupta, R, Pearson, E, Adamski, J, 't Hart, L

Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function Tekijä Hawe, JS, Wilson, R, Schmid, KT, Zhou, L, Lakshmanan, LN, Lehne, BC, Kühnel, B, Scott, WR, Wielscher, M, Yew, YW, Baumbach, C, Lee, DP, Marouli, E, Bernard, M, Pfeiffer, L, Matías-García, PR, Autio, MI, Bourgeois, S, Herder, C, Karhunen, V, Meitinger, T, Prokisch, H, Rathmann, W, Roden, M, Sebert, S, Shin, J, Strauch, K, Zhang, W, Tan, WLW, Hauck, SM, Merl-Pham, J, Grallert, H, Barbosa, EGV, MuTHER Consortium, Illig, T, Peters, A, Paus, T, Pausova, Z, Deloukas, P, Foo, RSY, Jarvelin, M-R, Kooner, JS, Loh, M, Heinig, M, Gieger, C, Waldenberger, M, Chambers, JC

Genetic predisposition to coronary artery disease in type 2 diabetes Tekijä van Zuydam, NR, Ladenvall, C, Voight, BF, Strawbridge, RJ, Fernandez Tajes, J, Rayner, NW, Robertson, NR, Mahajan, A, Vlachopoulou, E, Goel, A, Kleber, ME, Nelson, CP, Kwee, LC, Esko, T, Mihailov, E, Mägi, R, Milani, L, Fischer, K, Kanoni, S, Kumar, J, Song, C, Hartiala, JA, Pedersen, NL, Perola, M, Gieger, C, Peters, A, Qu, L, Willems, SM, Doney, ASF, Morris, AD, Zheng, Y, Sesti, G, Hu, FB, Qi, L, Laakso, M, Thorsteinsdottir, U, Grallert, H, van Duijn, C, Reilly, MP, Ingelsson, E, Deloukas, P, Kathiresan, S, Metspalu, A, Shah, SH, Sinisalo, J, Salomaa, V, Hamsten, A, Samani, NJ, März, W, Hazen, SL, Watkins, H

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. Tekijä Kolz, M, Johnson, T, Sanna, S, Teumer, A, Vitart, V, Perola, M, Mangino, M, Albrecht, E, Wallace, C, Farrall, M, Johansson, A, Nyholt, DR, Aulchenko, Y, Beckmann, J, Bergmann, S, Bochud, M, Brown, M, Campbell, H, Connell, J, Dominiczak, A, Homuth, G, Lamina, C, McCarthy, M, Meitinger, T, Mooser, V, Munroe, P, Nauck, M, Peden, J, Prokisch, H, Salo, P, Salomaa, V, Samani, N, Schlessinger, D, Uda, M, Volker, U, Waeber, G, Waterworth, D, Wang-Sattler, R, Wright, A, Adamski, J, Whitfield, J, Gyllensten, U, Wilson, J, Rudan, I, Pramstaller, P, Watkins, H, Doering, A, Wichmann, H, Spector, T, Peltonen, L, Volzke, H, Nagaraja, R, Vollenweider, P, Caulfield, M, Illig, T, Gieger, C

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus Tekijä Mathieson, I, Day, FR, Barban, N, Tropf, FC, Brazel, DM, eQTLGen Consortium, BIOS Consortium, Vaez, A, van Zuydam, N, Bitarello, BD, Gardner, EJ, Akimova, ET, Azad, A, Bergmann, S, Bielak, LF, Boomsma, DI, Bosak, K, Brumat, M, Buring, JE, Cesarini, D, Chasman, DI, Chavarro, JE, Cocca, M, Concas, MP, Davey Smith, G, Davies, G, Deary, IJ, Esko, T, Faul, JD, FinnGen Study, Franco, O, Ganna, A, Gaskins, AJ, Gelemanovic, A, de Geus, EJC, Gieger, C, Girotto, G, Gopinath, B, Grabe, HJ, Gunderson, EP, Hayward, C, He, C, van Heemst, D, Hill, WD, Hoffmann, ER, Homuth, G, Hottenga, JJ, Huang, H, Hyppӧnen, E, Ikram, MA, Mills, MC

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study Tekijä Chambers, JC, Loh, M, Lehne, B, Drong, A, Kriebel, J, Motta, V, Wahl, S, Elliott, HR, Rota, F, Scott, WR, Zhang, W, Tan, S-T, Campanella, G, Chadeau-Hyam, M, Yengo, L, Richmond, RC, Adamowicz-Brice, M, Afzal, U, Bozaoglu, K, Mok, ZY, Ng, HK, Pattou, F, Prokisch, H, Rozario, MA, Tarantini, L, Abbott, J, Ala-Korpela, M, Albetti, B, Ammerpohl, O, Bertazzi, PA, Blancher, C, Caiazzo, R, Danesh, J, Gaunt, TR, de Lusignan, S, Gieger, C, Illig, T, Jha, S, Jones, S, Jowett, J, Kangas, AJ, Kasturiratne, A, Kato, N, Kotea, N, Kowlessur, S, Pitkäniemi, J, Punjabi, P, Saleheen, D, Schafmayer, C, Soininen, P, Tai, ES, Thorand, B, Tuomilehto, J, Wickremasinghe, AR, Kyrtopoulos, SA, Aitman, TJ, Herder, C, Hampe, J, Cauchi, S, Relton, CL, Froguel, P, Soong, R, Vineis, P, Jarvelin, MR, Scott, J, Grallert, H, Bollati, V, Elliott, P, McCarthy, MI, Kooner, JS

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke Tekijä Cole, J, Xu, H, Ryan, K, Jaworek, T, Dueker, N, McArdle, P, Gaynor, B, Cheng, Y, O'Connell, J, Bevan, S, Malik, R, Ahmed, N, Amouyel, P, Anjum, S, Bis, J, Crosslin, D, Danesh, J, Engelter, S, Fornage, M, Frossard, P, Gieger, C, Giese, A, Grond-Ginsbach, C, Ho, W, Holliday, E, Hopewell, J, Hussain, M, Iqbal, W, Jabeen, S, Jannes, J, Kamal, A, Kamatani, Y, Kanse, S, Kloss, M, Lathrop, M, Leys, D, Lindgren, A, Longstreth, W, Mahmood, K, Meisinger, C, Metso, T, Mosley, T, Müller-Nurasyid, M, Norrving, B, Parati, E, Peters, A, Pezzini, A, Quereshi, I, Rasheed, A, Rauf, A, Salam, T, Shen, J, Słowik, A, Stanne, T, Strauch, K, Tatlisumak, T, Thijs, V, Tiedt, S, Traylor, M, Waldenberger, M, Walters, M, Zhao, W, Boncoraglio, G, Debette, S, Jern, C, Levi, C, Markus, H, Meschia, J, Rolfs, A, Rothwell, P, Saleheen, D, Seshadri, S, Sharma, P, Sudlow, C, Worrall, B, Metastroke Consortium Of The Isgc, Wtccc-2 Consortium, Stine, O, Kittner, S, Mitchell, B