Pilot RNAi screening using mammalian cell-based system identifies novel putative silencing factors including Kat5/Tip60 by Anuroop Venkateswaran Venkatasubramani, Katy McLaughlin, Giovanny Rodriguez Blanco, Vladimir Larionov, Alexander Kagansky

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Probiotics prevent cartilage damage and progression of osteoarthritis in mice by Antonia Sophocleous, Asim Azfer, Carmen Huesa, Eleni Stylianou, Giovanny Rodriguez Blanco, Stuart H. Ralston

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Gender-Specific Bile Acid Profiles in Non-Alcoholic Fatty Liver Disease by Julia Fitzinger, Giovanny Rodriguez-Blanco, Markus Herrmann, Andrea Borenich, Rudolf Stauber, Elmar Aigner, Harald Mangge

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Lipids contribute to epigenetic control via chromatin structure and functions by Renad Zhdanov, Eric Schirmer, Anuroop Venkateswaran Venkatasubramani, Alastair Kerr, Elena Mandrou, Giovanny Rodriguez Blanco, Alexander Kagansky

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Lipids contribute to epigenetic control via chromatin structure and functions by Renad Zhdanov, Eric Schirmer, Anuroop Venkateswaran Venkatasubramani, Alastair Kerr, Elena Mandrou, Giovanny Rodriguez Blanco, Alexander Kagansky

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Cytoglobin protects cancer cells from apoptosis by regulation of mitochondrial cardiolipin by Lorna S. Thorne, Garret Rochford, Timothy D. Williams, Andrew D. Southam, Giovanny Rodriguez-Blanco, Warwick B. Dunn, Nikolas J. Hodges

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Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium by Xuan Wang-Kan, Giovanny Rodríguez-Blanco, Andrew D. Southam, Catherine L. Winder, Warwick B. Dunn, Alasdair Ivens, Laura J. V. Piddock

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Metabolomic Alterations of Volatile Organic Compounds and Bile Acids as Biomarkers of Microbial Shifts in a Murine Model of Short Bowel Syndrome by Vanessa Wolfschluckner, Beate Obermüller, Angela Horvath, Giovanny Rodriguez-Blanco, Patricia Fuchs, Wolfram Miekisch, Barbara Mittl, Christina Flucher, Holger Till, Georg Singer

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Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer by Aitor Almanza, Katarzyna Mnich, Arnaud Blomme, Claire M. Robinson, Giovanny Rodriguez-Blanco, Sylwia Kierszniowska, Eoghan P. McGrath, Matthieu Le Gallo, Eleftherios Pilalis, Johannes V. Swinnen, Aristotelis Chatziioannou, Eric Chevet, Adrienne M. Gorman, Afshin Samali

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Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism by Dylan Gerard Ryan, Ming Yang, Hiran A Prag, Giovanny Rodriguez Blanco, Efterpi Nikitopoulou, Marc Segarra-Mondejar, Christopher A Powell, Tim Young, Nils Burger, Jan Lj Miljkovic, Michal Minczuk, Michael P Murphy, Alex von Kriegsheim, Christian Frezza

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Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice by Jonas Eckrich, Katie Frenis, Giovanny Rodriguez-Blanco, Yue Ruan, Subao Jiang, Maria Teresa Bayo Jimenez, Marin Kuntic, Matthias Oelze, Omar Hahad, Huige Li, Adrian Gericke, Sebastian Steven, Sebastian Strieth, Alex von Kriegsheim, Thomas Münzel, Benjamin Philipp Ernst, Andreas Daiber

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Fluid shear stress induces a shift from glycolytic to amino acid pathway in human trophoblasts by Beatrice Anna Brugger, Lena Neuper, Jacqueline Guettler, Désirée Forstner, Stefan Wernitznig, Daniel Kummer, Freya Lyssy, Julia Feichtinger, Julian Krappinger, Amin El-Heliebi, Lilli Bonstingl, Gerit Moser, Giovanny Rodriguez-Blanco, Olaf A. Bachkönig, Benjamin Gottschalk, Michael Gruber, Olivia Nonn, Florian Herse, Stefan Verlohren, Hans-Georg Frank, Nirav Barapatre, Cornelia Kampfer, Herbert Fluhr, Gernot Desoye, Martin Gauster

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2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer by Arnaud Blomme, Catriona A. Ford, Ernest Mui, Rachana Patel, Chara Ntala, Lauren E. Jamieson, Mélanie Planque, Grace H. McGregor, Paul Peixoto, Eric Hervouet, Colin Nixon, Mark Salji, Luke Gaughan, Elke Markert, Peter Repiscak, David Sumpton, Giovanny Rodriguez Blanco, Sergio Lilla, Jurre J. Kamphorst, Duncan Graham, Karen Faulds, Gillian M. MacKay, Sarah-Maria Fendt, Sara Zanivan, Hing Y. Leung

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Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche by Amy Dawson, Martha M. Zarou, Bodhayan Prasad, Joana Bittencourt-Silvestre, Désirée Zerbst, Ekaterini Himonas, Ya-Ching Hsieh, Isabel van Loon, Giovanny Rodriguez Blanco, Angela Ianniciello, Zsombor Kerekes, Vaidehi Krishnan, Puneet Agarwal, Hassan Almasoudi, Laura McCluskey, Lisa E. M. Hopcroft, Mary T. Scott, Pablo Baquero, Karen Dunn, David Vetrie, Mhairi Copland, Ravi Bhatia, Seth B. Coffelt, Ong Sin Tiong, Helen Wheadon, Sara Zanivan, Kristina Kirschner, G. Vignir Helgason

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MYC sensitises cells to apoptosis by driving energetic demand by Joy Edwards-Hicks, Huizhong Su, Maurizio Mangolini, Kubra K. Yoneten, Jimi Wills, Giovanny Rodriguez-Blanco, Christine Young, Kevin Cho, Heather Barker, Morwenna Muir, Ania Naila Guerrieri, Xue-Feng Li, Rachel White, Piotr Manasterski, Elena Mandrou, Karen Wills, Jingyu Chen, Emily Abraham, Kianoosh Sateri, Bin-Zhi Qian, Peter Bankhead, Mark Arends, Noor Gammoh, Alex von Kriegsheim, Gary J. Patti, Andrew H. Sims, Juan Carlos Acosta, Valerie Brunton, Kamil R. Kranc, Maria Christophorou, Erika L. Pearce, Ingo Ringshausen, Andrew J. Finch

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­­­­­­­A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS­­­ [version 2; peer review: 1 approved, 3 approved with reservations]... by Leila Reyes, Manuel A. Sanchez-Garcia, Tyler Morrison, Andy J. M. Howden, Emily R. Watts, Simone Arienti, Pranvera Sadiku, Patricia Coelho, Ananda S. Mirchandani, Ailiang Zhang, David Hope, Sarah K. Clark, Jo Singleton, Shonna Johnston, Robert Grecian, Azin Poon, Sarah McNamara, Isla Harper, Max Head Fourman, Alejandro J. Brenes, Shalini Pathak, Amy Lloyd, Giovanny Rodriguez Blanco, Alex von Kriegsheim, Bart Ghesquiere, Wesley Vermaelen, Camila T. Cologna, Kevin Dhaliwal, Nik Hirani, David H. Dockrell, Moira K. B. Whyte, David Griffith, Doreen A. Cantrell, Sarah R. Walmsley

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­­­­­­­A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS­­­ [version 1; peer review: 1 approved, 3 approved with reservations]... by Leila Reyes, Manuel A. Sanchez-Garcia, Tyler Morrison, Andy J. M. Howden, Emily R. Watts, Simone Arienti, Pranvera Sadiku, Patricia Coelho, Ananda S. Mirchandani, Ailiang Zhang, David Hope, Sarah K. Clark, Jo Singleton, Shonna Johnston, Robert Grecian, Azin Poon, Sarah McNamara, Isla Harper, Max Head Fourman, Alejandro J. Brenes, Shalini Pathak, Amy Lloyd, Giovanny Rodriguez Blanco, Alex von Kriegsheim, Bart Ghesquiere, Wesley Vermaelen, Camila T. Cologna, Kevin Dhaliwal, Nik Hirani, David H. Dockrell, Moira K. B. Whyte, David Griffith, Doreen A. Cantrell, Sarah R. Walmsley

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THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer by Arnaud Blomme, Coralie Peter, Ernest Mui, Giovanny Rodriguez Blanco, Ning An, Louise M Mason, Lauren E Jamieson, Grace H McGregor, Sergio Lilla, Chara Ntala, Rachana Patel, Marc Thiry, Sonia H Y Kung, Marine Leclercq, Catriona A Ford, Linda K Rushworth, David J McGarry, Susan Mason, Peter Repiscak, Colin Nixon, Mark J Salji, Elke Markert, Gillian M MacKay, Jurre J Kamphorst, Duncan Graham, Karen Faulds, Ladan Fazli, Martin E Gleave, Edward Avezov, Joanne Edwards, Huabing Yin, David Sumpton, Karen Blyth, Pierre Close, Daniel J Murphy, Sara Zanivan, Hing Y Leung

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