In Memory of Professor John Gordon McVie: Bringing People Together 13 January 1945 – 20 January 2021 by Giuseppe Giaccone

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Challenges in Diversity, Equity, and Inclusion in Research and Clinical Oncology by Wafik S. El-Deiry, Giuseppe Giaccone

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Molecular predictors of response to pembrolizumab in thymic carcinoma by Yongfeng He, Archana Ramesh, Yuriy Gusev, Krithika Bhuvaneshwar, Giuseppe Giaccone

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A Phase I Trial of Dasatinib and Osimertinib in TKI Naïve Patients With Advanced EGFR-Mutant Non-Small-Cell Lung Cancer by Chul Kim, Stephen V. Liu, Jennifer Crawford, Tisdrey Torres, Vincent Chen, Jillian Thompson, Ming Tan, Giuseppe Esposito, Deepa S. Subramaniam, Deepa S. Subramaniam, Giuseppe Giaccone, Giuseppe Giaccone

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A Phase Ib/II Study of Ganetespib With Doxorubicin in Advanced Solid Tumors Including Relapsed-Refractory Small Cell Lung Cancer by Deepa S. Subramaniam, Stephen V. Liu, Jeanette Crawford, Jenna Kramer, Jillian Thompson, Hongkun Wang, Giuseppe Giaccone

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Whole genome and transcriptome sequencing of a B3 thymoma. by Iacopo Petrini, Arun Rajan, Trung Pham, Donna Voeller, Sean Davis, James Gao, Yisong Wang, Giuseppe Giaccone

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MicroRNA expression and clinical outcome of small cell lung cancer. by Jih-Hsiang Lee, Johannes Voortman, Anne-Marie C Dingemans, Donna M Voeller, Trung Pham, Yisong Wang, Giuseppe Giaccone

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A Network Meta-Analysis of Cancer Immunotherapies Versus Chemotherapy for First-Line Treatment of Patients With Non-Small Cell Lung Cancer and High Programmed Death-Ligand 1 Expres... by Roy Herbst, Jacek Jassem, Seye Abogunrin, Daniel James, Rachael McCool, Rossella Belleli, Giuseppe Giaccone, Filippo De Marinis

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Reproducibility of pharmacogenetics findings for paclitaxel in a heterogeneous population of patients with lung cancer. by Tristan M Sissung, Arun Rajan, Gideon M Blumenthal, David J Liewehr, Seth M Steinberg, Arlene Berman, Giuseppe Giaccone, William D Figg

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Inhibition of AKT1 signaling promotes invasion and metastasis of non-small cell lung cancer cells with K-RAS or EGFR mutations by Guanhua Rao, Mariaelena Pierobon, In-Kyu Kim, Wei-Hsun Hsu, Jianghong Deng, Yong-Wha Moon, Emanuel F. Petricoin, Yu-Wen Zhang, Yisong Wang, Giuseppe Giaccone

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The Prognostic Value of Non-Predominant Micropapillary Pattern in a Large Cohort of Resected Invasive Lung Adenocarcinoma Measuring ≤3 cm by Hua Zhang, Wuhao Huang, Chang Liu, Giuseppe Giaccone, Xiaoliang Zhao, Xiaoyan Sun, Jingjing Li, Runfen Cheng, Qiujuan Huang, Huilan Mo, Zhenfa Zhang, Bin Zhang, Changli Wang

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Cardiomyocyte-Specific Circulating Cell-Free Methylated DNA in Esophageal Cancer Patients Treated with Chemoradiation by Sarah Martinez Roth, Eveline E. Vietsch, Megan E. Barefoot, Marcel O. Schmidt, Matthew D. Park, Archana Ramesh, Michael R. Lindberg, Giuseppe Giaccone, Anna T. Riegel, Ana Barac, Keith Unger, Anton Wellstein

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Acquired small cell lung cancer resistance to Chk1 inhibitors involves Wee1 up‐regulation by Xiaoliang Zhao, In‐Kyu Kim, Bhaskar Kallakury, Joeffrey J. Chahine, Eiji Iwama, Mariaelena Pierobon, Emanuel Petricoin, Justine N. McCutcheon, Yu‐Wen Zhang, Shigeki Umemura, Vincent Chen, Changli Wang, Giuseppe Giaccone

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Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential target. by Mariëlle I Gallegos Ruiz, Karijn Floor, Paul Roepman, José A Rodriguez, Gerrit A Meijer, Wolter J Mooi, Ewa Jassem, Jacek Niklinski, Thomas Muley, Nico van Zandwijk, Egbert F Smit, Kristin Beebe, Len Neckers, Bauke Ylstra, Giuseppe Giaccone

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Surrogate endpoints for overall survival in randomized clinical trials testing immune checkpoint inhibitors: a systematic review and meta-analysis by Isabella Sala, Isabella Sala, Eleonora Pagan, Laura Pala, Chiara Oriecuia, Chiara Oriecuia, Marco Musca, Marco Musca, Claudia Specchia, Tommaso De Pas, Javier Cortes, Javier Cortes, Javier Cortes, Giuseppe Giaccone, Michael Postow, Richard D. Gelber, Vincenzo Bagnardi, Fabio Conforti, Fabio Conforti

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High-Risk Non-Small Cell Lung Cancer Treated With Active Scanning Proton Beam Radiation Therapy and Immunotherapy by Michael Carrasquilla, MD, Nitika Paudel, MD, PhD, Brian T. Collins, MD, Eric Anderson, MD, Rebecca Krochmal, MD, Marc Margolis, MD, Ahssan Balawi, MS, CMD, David DeBlois, BS, CMD, Giuseppe Giaccone, MD, PhD, Chul Kim, MD, Stephen Liu, MD, Jonathan W. Lischalk, MD

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Image microarrays (IMA): Digital pathology′s missing tool by Jason Hipp, Jerome Cheng, Liron Pantanowitz, Stephen Hewitt, Yukako Yagi, James Monaco, Anant Madabhushi, Jaime Rodriguez-canales, Jeffrey Hanson, Sinchita Roy-Chowdhuri, Armando C Filie, Michael D Feldman, John E Tomaszewski, Natalie NC Shih, Victor Brodsky, Giuseppe Giaccone, Michael R Emmert-Buck, Ulysses J Balis

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American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non–Small-Cell Lung Cancer by Giuseppe GIACCONE, David TRENT, John R. STRAWN, Reily SMITH, Thomas J. SMITH, Joan H. SCHILLER, David G. PFISTER, Steven PIANTADOSI, Luke NORDQUIST, Daniel MILTON, Gregory MASTERS, Janessa L. LASKI, David H. JOHNSON, Julie BRAHMER, William PAO, Timothy ALIFF, Sarah TEMIN, Sherman Baker JR, Christopher G. AZZOLI

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606 IMpower110: Tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first-line atezolizumab or chemotherapy by Robert Johnston, Hartmut Koeppen, Roy S Herbst, Kurt Schalper, Filippo De Marinis, Giuseppe Giaccone, Jacek Jassem, Marcus Ballinger, Barani Kumar Rajendran, David R Spigel, Miguel López de Rodas, Minu K Srivastava, Jennifer M Giltnane, Barzin Y Nabet, David S Shames, Velimir Gayevskiy, Vy Ma, Ivette Estay, Tien Hoang, Reena Amin

Pulmonary cancers across different histotypes share hybrid tuft cell/ionocyte-like molecular features and potentially druggable vulnerabilities by Yosuke Yamada, Djeda Belharazem-Vitacolonnna, Hanibal Bohnenberger, Christel Weiß, Naoko Matsui, Mark Kriegsmann, Katharina Kriegsmann, Peter Sinn, Katja Simon-Keller, Gerhard Hamilton, Thomas Graeter, Gerhard Preissler, German Ott, Sebastian Schölch, Naoki Nakajima, Akihiko Yoshizawa, Hironori Haga, Hiroshi Date, Roman K. Thomas, Iacopo Petrini, Giuseppe Giaccone, Philipp Ströbel, Alexander Marx

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