A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors by Buono, M, Giustacchini, A, Mead, A, Jacobsen, S, Nerlov, C, Facchini, R, Matsuoka, S, Thongjuea, S, Luis, T, Besmer, P

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program by Loughran, S, Comoglio, F, Hamey, F, Giustacchini, A, Errami, Y, Earp, E, Göttgens, B, Jacobsen, S, Mead, A, Hendrich, B, Green, A

Single cell RNA sequencing reveals molecular and functional platelet bias of aged hematopoietic stem cells by Nerlov, C, Grover, A, Giustacchini, A, Gambardella, A, Macaulay, I, Mead, A, Jacobsen, S, Sanjuan-Pla, A, Thongjuea, S, Carrelha, J, Mancini, E, Luis, T

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics by Handel, A, Chintawar, S, Lalic, T, Whiteley, E, Vowles, J, Giustacchini, A, Argoud, K, Sopp, P, Nakanishi, M, Bowden, R, Cowley, S, Newey, S, Akerman, C, Ponting, C, Cader, M

Disruption of haematopoietic stem cell heterogeniety in a mouse model of myelproliferate neoplasm by Norfo, R, Di Genua, C, Booth, C, Giustacchini, A, Povinelli, B, Gray, N, Repapi, E, Soilleux, E, Jamieson, L, Tran, N, Green, A, Jacobsen, S, Mead, A

Distinct myeloid progenitor differentiation pathways identified through single cell RNA sequencing by Drissen, R, Buza-Vidas, N, Woll, P, Thongjuea, S, Gambardella, A, Giustacchini, A, Mancini, E, Zriwil, A, Lutteropp, M, Grover, A, Mead, A, Sitnicka, E, Jacobsen, S, Nerlov, C

Unravelling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA sequencing by Rodriguez-Meira, A, Buck, G, Clark, S, Povinelli, B, Alcolea, V, Louka, E, McGowan, S, Hamblin, A, Sousos, N, Barkas, N, Giustacchini, A, Psaila, B, Jacobsen, S, Thongjuea, S, Mead, A

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation by Mead, A, Neo, W, Barkas, N, Matsuoka, S, Giustacchini, A, Facchini, R, Thongjuea, S, Jamieson, L, Booth, C, Fordham, N, Di Genua, C, Atkinson, D, Chowdhury, O, Repapi, E, Gray, N, Kharazi, S, Clark, S, Bouriez, T, Woll, P, Suda, T, Nerlov, C, Jacobsen, S

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia by Giustacchini, A, Thongjuea, S, Barkas, N, Woll, P, Povinelli, B, Booth, C, Sopp, P, Norfo, R, Rodriguez-Meira, A, Ashley, N, Jamieson, L, Vyas, P, Anderson, K, Segerstolpe, Å, Qian, H, Olsson-Strömberg, U, Mustjoki, S, Sandberg, R, Jacobsen, S, Mead, A

Ezh2 and Runx1 mutations collaborate to initiate lympho-myeloid leukemia in early thymic progenitors by Booth, CAG, Barkas, N, Neo, WH, Boukarabila, H, Soilleux, EJ, Giotopoulos, G, Farnoud, N, Giustacchini, A, Ashley, N, Carrelha, J, Jamieson, L, Atkinson, D, Bouriez-Jones, T, Prinjha, RK, Milne, TA, Teachey, DT, Papaemmanuil, E, Huntly, BJP, Jacobsen, SEW, Mead, AJ

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner by Luis, TC, Barkas, N, Carrelha, J, Giustacchini, A, Mazzi, S, Norfo, R, Wu, B, Aliouat, A, Guerrero, JA, Rodriguez-Meira, A, Bouriez-Jones, T, Macaulay, IC, Jasztal, M, Zhu, G, Ni, H, Robson, MJ, Blakely, RD, Mead, AJ, Nerlov, C, Ghevaert, C, Jacobsen, SEW

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors by Luis, T, Luc, S, Mizukami, T, Boukarabila, H, Thongjuea, S, Woll, P, Azzoni, E, Giustacchini, A, Lutteropp, M, Bouriez-Jones, T, Vaidya, H, Mead, A, Atkinson, D, Böiers, C, Carrelha, J, Macaulay, I, Patient, R, Geissmann, F, Nerlov, C, Sandberg, R, De Bruijn, M, Blackburn, C, Godin, I, Jacobsen, S

Erratum to Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo [Cancer Cell, 25 (2014) 794-808] by Woll, P, Kjällquist, U, Chowdhury, O, Doolittle, H, Wedge, D, Thongjuea, S, Erlandsson, R, Ngara, M, Anderson, K, Deng, Q, Mead, A, Stenson, L, Giustacchini, A, Duarte, S, Giannoulatou, E, Taylor, S, Karimi, M, Scharenberg, C, Mortera-Blanco, T, Macaulay, I, Clark, S, Dybedal, I, Josefsen, D, Fenaux, P, Hokland, P

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo by Woll, P, Kjällquist, U, Chowdhury, O, Doolittle, H, Wedge, D, Thongjuea, S, Erlandsson, R, Ngara, M, Anderson, K, Deng, Q, Mead, A, Stenson, L, Giustacchini, A, Duarte, S, Giannoulatou, E, Taylor, S, Karimi, M, Scharenberg, C, Mortera-Blanco, T, Macaulay, I, Clark, S, Dybedal, I, Josefsen, D, Fenaux, P, Hokland, P

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo. by Woll, P, Kjällquist, U, Chowdhury, O, Doolittle, H, Wedge, D, Thongjuea, S, Erlandsson, R, Ngara, M, Anderson, K, Deng, Q, Mead, A, Stenson, L, Giustacchini, A, Duarte, S, Giannoulatou, E, Taylor, S, Karimi, M, Scharenberg, C, Mortera-Blanco, T, Macaulay, I, Clark, SA, Dybedal, I, Josefsen, D, Fenaux, P, Hokland, P, Holm, MS, Cazzola, M, Malcovati, L, Tauro, S, Bowen, D, Boultwood, J, Pellagatti, A, Pimanda, J, Unnikrishnan, A, Vyas, P, Göhring, G, Schlegelberger, B, Tobiasson, M, Kvalheim, G, Constantinescu, SN, Nerlov, C, Nilsson, L, Campbell, P, Sandberg, R, Papaemmanuil, E, Hellström-Lindberg, E, Linnarsson, S, Jacobsen, S