Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo 由 Simon, C, Downes, D, Gosden, M, Telenius, J, Higgs, D, Hughes, J, Costello, I, Bikoff, E, Robertson, E

DeepC: Predicting 3D genome folding using megabase-scale transfer learning 由 Schwessinger, R, Gosden, M, Downes, D, Brown, RC, Oudelaar, AM, Telenius, J, Teh, YW, Lunter, G, Hughes, JR

Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo 由 Hanssen, L, Kassouf, M, Oudelaar, A, Biggs, D, Preece, C, Downes, D, Gosden, M, Sharpe, J, Sloane-Stanley, J, Hughes, J, Davies, B, Higgs, D

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin 由 Truch, J, Downes, DJ, Scott, C, Gür, ER, Telenius, JM, Repapi, E, Schwessinger, R, Gosden, M, Brown, JM, Taylor, S, Cheong, PL, Hughes, JR, Higgs, DR, Gibbons, RJ

The α-globin super-enhancer acts in an orientation-dependent manner 由 Kassouf, MT, Francis, HS, Gosden, M, Suciu, MC, Downes, DJ, Harrold, C, Larke, M, Oudelaar, M, Cornell, L, Blayney, J, Telenius, J, Xella, B, Shen, Y, Sousos, N, Sharpe, JA, Sloane-Stanley, J, Smith, AJH, Babbs, C, Hughes, JR, Higgs, DR

Recapitulation of erythropoiesis in congenital dyserythropoietic anaemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities 由 Scott, C, Downes, DJ, Brown, J, Beagrie, R, Olijnik, AA, Gosden, M, Schwessinger, R, Fisher, C, Rose, A, Ferguson, D, Johnson, E, Hill, Q, Okoli, S, Renella, R, Ryan, K, Brand, M, Hughes, J, Roy, N, Higgs, D, Babbs, C, Buckle, V

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia 由 Mettananda, S, Fisher, C, Hay, D, Badat, M, Quek, L, Clark, K, Hublitz, P, Downes, D, Kerry, J, Gosden, M, Telenius, J, Sloane-Stanley, J, Faustino, P, Coelho, A, Doondeea, J, Usukhbayar, B, Sopp, P, Sharpe, J, Hughes, J, Vyas, P, Gibbons, R, Higgs, D