Modeling T cell antigen discrimination based on feedback control of digital ERK responses. by Grégoire Altan-Bonnet, Ronald N Germain

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Noise-driven causal inference in biomolecular networks. by Robert J Prill, Robert Vogel, Guillermo A Cecchi, Grégoire Altan-Bonnet, Gustavo Stolovitzky

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T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar Antigens by Guillaume Voisinne, Briana G. Nixon, Anna Melbinger, Georg Gasteiger, Massimo Vergassola, Grégoire Altan-Bonnet

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1317-A Analyzing the immunological variability in T cell/tumor interactions to identify a subpopulation of CD8+ T cells (Spark T cells) that drives successful cancer immunotherapy... by Grégoire Altan-Bonnet, Dongya Jia, Emanuel Salazar Cavazos, Adam Kenet, Hannah Dada, Sooraj R Achar

773 Adoptive Cell Therapy Response in Melanoma is Mediated by Stem-like CD8 T cells by Steven Rosenberg, Paul Robbins, Stephanie Goff, Frank Lowery, Sri Krishna, Amy Copeland, Grégoire Altan-Bonnet

EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines by Debyani Chakravarty, Alicia M. Pedraza, Jesse Cotari, Angela H. Liu, Diana Punko, Aushim Kokroo, Jason T. Huse, Gregoire Altan-Bonnet, Cameron W. Brennan

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HAL-X: Scalable hierarchical clustering for rapid and tunable single-cell analysis. by James Anibal, Alexandre G Day, Erol Bahadiroglu, Liam O'Neil, Long Phan, Alec Peltekian, Amir Erez, Mariana Kaplan, Grégoire Altan-Bonnet, Pankaj Mehta

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Correction: Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges. by Robert J. Prill, Daniel Marbach, Julio Saez-Rodriguez, Peter K. Sorger, Leonidas G. Alexopoulos, Xiaowei Xue, Neil D. Clarke, Gregoire Altan-Bonnet, Gustavo Stolovitzky

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Single‐cell quantification of IL‐2 response by effector and regulatory T cells reveals critical plasticity in immune response by Ofer Feinerman, Garrit Jentsch, Karen E Tkach, Jesse W Coward, Matthew M Hathorn, Michael W Sneddon, Thierry Emonet, Kendall A Smith, Grégoire Altan‐Bonnet

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Towards a rigorous assessment of systems biology models: the DREAM3 challenges. by Robert J Prill, Daniel Marbach, Julio Saez-Rodriguez, Peter K Sorger, Leonidas G Alexopoulos, Xiaowei Xue, Neil D Clarke, Gregoire Altan-Bonnet, Gustavo Stolovitzky

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T cell receptor and IL-2 signaling strength control memory CD8+ T cell functional fitness via chromatin remodeling by Shu Shien Chin, Erik Guillen, Laurent Chorro, Sooraj Achar, Karina Ng, Susanne Oberle, Francesca Alfei, Dietmar Zehn, Grégoire Altan-Bonnet, Fabien Delahaye, Grégoire Lauvau

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T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks by Karen E Tkach, Debashis Barik, Guillaume Voisinne, Nicole Malandro, Matthew M Hathorn, Jesse W Cotari, Robert Vogel, Taha Merghoub, Jedd Wolchok, Oleg Krichevsky, Grégoire Altan-Bonnet

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TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors by Marion V. Guerin, Fabienne Regnier, Vincent Feuillet, Lene Vimeux, Julia M. Weiss, Georges Bismuth, Gregoire Altan-Bonnet, Thomas Guilbert, Maxime Thoreau, Veronica Finisguerra, Emmanuel Donnadieu, Alain Trautmann, Nadège Bercovici

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Determinants of Ligand Specificity and Functional Plasticity in Type I Interferon Signaling by Duncan Kirby, Baljyot Parmar, Sepehr Fathi, Sagar Marwah, Chitra R. Nayak, Chitra R. Nayak, Vera Cherepanov, Sonya MacParland, Jordan J. Feld, Grégoire Altan-Bonnet, Anton Zilman, Anton Zilman

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Inducible nitric oxide synthase-derived extracellular nitric oxide flux regulates proinflammatory responses at the single cell level by Veena Somasundaram, Anne C. Gilmore, Debashree Basudhar, Erika Mariana Palmieri, David A. Scheiblin, William F. Heinz, Robert.Y.S. Cheng, Lisa A. Ridnour, Grégoire Altan-Bonnet, Stephen J. Lockett, Daniel W. McVicar, David A. Wink

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Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells. by M Lia Palomba, Kelly Piersanti, Carly G K Ziegler, Hugo Decker, Jesse W Cotari, Kurt Bantilan, Ivelise Rijo, Jeff R Gardner, Mark Heaney, Debra Bemis, Robert Balderas, Sami N Malek, Erlene Seymour, Andrew D Zelenetz, Marcel R M van den Brink, Grégoire Altan-Bonnet

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Manufacture of CD22 CAR T cells following positive versus negative selection results in distinct cytokine secretion profiles and γδ T cell output by Hannah W. Song, Mehdi Benzaoui, Alka Dwivedi, Sarah Underwood, Lipei Shao, Sooraj Achar, Vesna Posarac, Victoria A. Remley, Michaela Prochazkova, Yihua Cai, Ping Jin, Robert P. Somerville, David F. Stroncek, Grégoire Altan-Bonnet, Nirali N. Shah, Christopher D. Chien, Naomi Taylor, Steven L. Highfill

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The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis by Qing Chang, Eirini Bournazou, Pasquale Sansone, Marjan Berishaj, Sizhi Paul Gao, Laura Daly, Jared Wels, Till Theilen, Selena Granitto, Xinmin Zhang, Jesse Cotari, Mary L. Alpaugh, Elisa de Stanchina, Katia Manova, Ming Li, Massimiliano Bonafe, Claudio Ceccarelli, Mario Taffurelli, Donatella Santini, Gregoire Altan-Bonnet, Rosandra Kaplan, Larry Norton, Norihiro Nishimoto, Dennis Huszar, David Lyden, Jacqueline Bromberg

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